2025
Patients’ Expectations for App-Based Therapy in Knee Osteoarthritis: User-Centered Design Approach
Mirt P, Erjavec K, Krsnik S, Kotnik P, Mohsen H. Patients’ Expectations for App-Based Therapy in Knee Osteoarthritis: User-Centered Design Approach. JMIR Rehabilitation And Assistive Technologies 2025, 12: e64607. PMID: 40373216, PMCID: PMC12097652, DOI: 10.2196/64607.Peer-Reviewed Original ResearchMobile health appsExercise videosKnee osteoarthritisKnee osteoarthritis managementHealth appsPotentials of mobile health technologiesDuration of physical activityImprove accessGoal settingMobile health technologyDisease informationHealth care systemSymptomatic knee osteoarthritisFace significant barriersKellgren-Lawrence scaleMixed methods approachPhysiotherapy accessPhysiotherapy servicesKnee exercisesPhysical activityImprove patient qualityElectronic remindersTelephone consultationsSelf-ManagementExpectancy of patientsRecent advances in the management of pediatric cholestatic liver diseases
Mysore K, Cheng K, Suri L, Fawaz R, Mavis A, Kogan‐Liberman D, Mohammad S, Taylor S. Recent advances in the management of pediatric cholestatic liver diseases. Journal Of Pediatric Gastroenterology And Nutrition 2025, 80: 549-558. PMID: 39840645, PMCID: PMC11961318, DOI: 10.1002/jpn3.12462.Peer-Reviewed Original ResearchPediatric cholestatic liver diseasesCholestatic liver diseaseIleal bile acid transporterAlagille syndromeSlow disease progressionLiver diseaseBile acid transporterMedical therapyIleal bile acid transporter inhibitorClinical trialsDisease progressionProgressive familial intrahepatic cholestasisFamilial intrahepatic cholestasisPediatric liver transplantationBile acid toxicityCurative medical therapyAcid transportImprove patient qualityIntrahepatic cholestasisBiliary atresiaSurgical managementRare conditionLiver transplantationNutritional supportUnderlying etiology
2024
The Financial Burden of Localized and Metastatic Bladder Cancer
Scilipoti P, Moschini M, Li R, Lerner S, Black P, Necchi A, Rouprêt M, Shariat S, Gupta S, Morgans A, Psutka S, Kamat A. The Financial Burden of Localized and Metastatic Bladder Cancer. European Urology 2024, 87: 536-550. PMID: 39730299, DOI: 10.1016/j.eururo.2024.12.002.Peer-Reviewed Original ResearchMetastatic bladder cancerFinancial toxicityBacillus Calmette-GuerinBladder cancerRadical cystectomyFinancial burdenImpact of bladder cancerNon-muscle-invasive BCaSystematic reviewHigh-risk NMIBC patientsMuscle-invasive BCaNMIBCBurden of bladder cancerEconomic burdenHealth care systemImprove oncologic outcomesTreatment-related toxicityPreferred Reporting ItemsHigher financial burdenBladder cancer managementCases of complicationsRisk of FTBladder cancer treatmentImprove patient qualityPatient perspectivePelvic Floor Physical Therapy Prehabilitation (PrePFPT) for the prevention of low anterior resection syndrome
Coppersmith N, Schultz K, Esposito A, Reinhart K, Ray E, Leeds I, Pantel H, Reddy V, Longo W, Mongiu A. Pelvic Floor Physical Therapy Prehabilitation (PrePFPT) for the prevention of low anterior resection syndrome. Surgical Oncology Insight 2024, 1: 100097. DOI: 10.1016/j.soi.2024.100097.Peer-Reviewed Original ResearchLow anterior resection syndromeAnterior resection syndromePelvic floor physical therapyQuality of life outcomesSymptoms of low anterior resection syndromeImprove patient qualityPhysical therapyRectal cancerPrehabilitationDevelopment of low anterior resection syndromeStudy designTreatment of low anterior resection syndromeTreatment of rectal cancerIncidence of low anterior resection syndromeLife outcomesEvaluated pre-Patients' qualityRectal cancer patientsCancer patientsDevelopment of symptomsNeoadjuvant chemoradiotherapyDefecatory dysfunctionImproved recoveryInternational trialsSyndromeEmbracing cancer complexity: Hallmarks of systemic disease
Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio M, Hidalgo A, Jamal-Hanjani M, Joyce J, Kaiser M, Lamia K, Locasale J, Loi S, Malanchi I, Merad M, Musgrave K, Patel K, Quezada S, Wargo J, Weeraratna A, White E, Winkler F, Wood J, Vousden K, Hanahan D. Embracing cancer complexity: Hallmarks of systemic disease. Cell 2024, 187: 1589-1616. PMID: 38552609, PMCID: PMC12077170, DOI: 10.1016/j.cell.2024.02.009.Peer-Reviewed Original ResearchConceptsHuman genetic variationSystemic diseaseHallmarks of cancerTumor-related thrombosisGenetic variationGene-environment interactionsCancer-related deathsComplexity of cancerMolecular basisTreat human cancersNervous system interactionsMechanisms of carcinogenesisHuman cancersImprove patient qualityCancer cachexiaSystemic manifestationsTumor micro-Cancer outcomesDistant organsTumor initiationMolecular oncologyTumorPatients' qualityPrevent cancerCancer
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