2024
Reproducibility of Semi-automated Quantitative Analyses of Tc-99m Pyrophosphate Uptake from Myocardial Perfusion Planar and SPECT Images
Goyal D, Sandoval V, Weyman C, Miller E, Liu Y. Reproducibility of Semi-automated Quantitative Analyses of Tc-99m Pyrophosphate Uptake from Myocardial Perfusion Planar and SPECT Images. Journal Of Medical And Biological Engineering 2024, 45: 84-91. DOI: 10.1007/s40846-024-00924-1.Peer-Reviewed Original ResearchStandardized uptake valueTc-99SPECT imagesStandard uptake value quantificationTransthyretin cardiac amyloidosisH/CL ratioTc-99m PYP uptakeMethodsOur study cohortInter-observer reproducibilityPlanar imagingTechnetium-99mCardiac amyloidosisClinical suspicionSPECT/CT imagingTc-99m PYP imagingTc-99m PYPConsecutive subjectsUptake valueObserver reproducibilityStudy cohortInter-observerPurposeThe aimResultsIntra-observerMyocardial uptakeSPECT
2023
Prevalence and significance of extracardiac uptake on pyrophosphate imaging in the SCAN-MP study: the first 379 cases.
Chan N, Einstein A, Griffin J, Rosenblum H, Teruya S, Cuomo M, De Los Santos J, DeLuca A, Johnson L, Kinkhabwala M, Leb J, Mintz A, Fine D, Helmke S, Muralidhar V, Pandey S, Sabogal N, Saith S, Winburn M, Smiley D, Miller E, Ruberg F, Maurer M. Prevalence and significance of extracardiac uptake on pyrophosphate imaging in the SCAN-MP study: the first 379 cases. Journal Of Nuclear Cardiology 2023, 30: 2531-2539. PMID: 38245059, DOI: 10.1007/s12350-023-03310-7.Peer-Reviewed Original ResearchConceptsTc-99m PYP uptakeExtracardiac uptakeATTR-CACardiac amyloidosisClinically actionable findingsDiagnose transthyretin cardiac amyloidosisTc-99Transthyretin cardiac amyloidosisBone uptakeTime of scanningBreast uptakeTc-99m PYP imagingThyroid uptakeHeart failureBlack raceRenal uptakeNuclear imagingPyrophosphate imagingTechnetium pyrophosphateHispanic ethnicityHispanic participantsNuclear scintigraphyMinority populationsClinicSelf-identify
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