2019
Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis
Ravimohan S, Auld SC, Maenetje P, Ratsela N, Mlotshwa M, Ncube I, Smith JP, Vangu MD, Sebe M, Kossenkov A, Weissman D, Wallis RS, Churchyard G, Kornfeld H, Bisson GP. Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis. Clinical Infectious Diseases 2019, 70: 1845-1854. PMID: 31242296, PMCID: PMC7156779, DOI: 10.1093/cid/ciz560.Peer-Reviewed Original ResearchConceptsPositron emission tomography-computed tomographyHuman immunodeficiency virusTotal glycolytic activityAntiretroviral therapyART initiationLung functionPulmonary tuberculosisLung inflammationLung injuryPulmonary inflammationMycobacteria-specific CD4 T cellsFluorodeoxyglucose positron emission tomography-computed tomographyCD4 T-cell restorationCD4 T cell functionCD4 T cell responsesEmission tomography-computed tomographyHuman immunodeficiency virus/tuberculosisT-cell restorationTB treatment completionWorse lung functionProspective cohort studyHIV/tuberculosisCD4 T cellsFDG PET-CTT cell responses
2015
Successful Tuberculosis Treatment Outcomes among HIV/TB Coinfected Patients Down-Referred from a District Hospital to Primary Health Clinics in Rural South Africa
Jacobson KB, Moll AP, Friedland GH, Shenoi SV. Successful Tuberculosis Treatment Outcomes among HIV/TB Coinfected Patients Down-Referred from a District Hospital to Primary Health Clinics in Rural South Africa. PLOS ONE 2015, 10: e0127024. PMID: 25993636, PMCID: PMC4438008, DOI: 10.1371/journal.pone.0127024.Peer-Reviewed Original ResearchConceptsTB treatment outcomesTB/HIVTreatment outcomesHIV clinicDistrict hospitalRetained patientsTreatment completionTreatment successRural South AfricaSuccessful tuberculosis treatment outcomeMajor public health threatDrug-susceptible TBHospital HIV clinicLinkage of careTB treatment completionTB treatment initiationTB treatment servicesTuberculosis treatment outcomesHIV/TBBaseline disease severityNew TB casesPrimary health clinicsPrimary care levelSpecific clinical criteriaHigher treatment success
2013
Methadone treatment improves tuberculosis treatment among hospitalized opioid dependent patients in Ukraine
Morozova O, Dvoryak S, Altice FL. Methadone treatment improves tuberculosis treatment among hospitalized opioid dependent patients in Ukraine. International Journal Of Drug Policy 2013, 24: e91-e98. PMID: 24360402, PMCID: PMC5553122, DOI: 10.1016/j.drugpo.2013.09.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidAntitubercular AgentsDelivery of Health Care, IntegratedDrug UsersFemaleHealth Knowledge, Attitudes, PracticeHeroin DependenceHumansInpatientsMaleMedication AdherenceMethadoneOpiate Substitution TreatmentProspective StudiesRisk FactorsTime FactorsTreatment OutcomeTuberculosisUkraineConceptsTB medication adherenceMethadone maintenanceTB treatmentMedication adherenceTreatment discontinuationMulti-drug resistant tuberculosisInpatient TB treatmentNumerous treatment challengesTB treatment completionOnly independent predictorOpioid-dependent patientsIndependent predictorsPrimary outcomeOpioid dependenceResistant tuberculosisMethadone treatmentTB facilitiesTreatment optionsDependent patientsTuberculosis treatmentTreatment completionTreatment challengesObservational studyMMT groupTreatment retention
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