2024
Transformation of metallo-elastomer grafts in a carotid artery interposition model over a year
Chen Y, Dombaxe C, D'Amato A, Van Herck S, Welch H, Fu Q, Zhang S, Wang Y. Transformation of metallo-elastomer grafts in a carotid artery interposition model over a year. Biomaterials 2024, 309: 122598. PMID: 38696943, DOI: 10.1016/j.biomaterials.2024.122598.Peer-Reviewed Original Research
2011
Development of Novel Biodegradable Polymer Scaffolds for Vascular Tissue Engineering
Gui L, Zhao L, Spencer RW, Burghouwt A, Taylor MS, Shalaby SW, Niklason LE. Development of Novel Biodegradable Polymer Scaffolds for Vascular Tissue Engineering. Tissue Engineering Part A 2011, 17: 1191-1200. PMID: 21143045, PMCID: PMC3079248, DOI: 10.1089/ten.tea.2010.0508.Peer-Reviewed Original ResearchConceptsTissue engineering approachesTissue-engineered blood vesselsBiodegradable polymer scaffoldsVascular tissue engineeringPolyglycolic acidDegradation profileTissue mechanicsEngineering approachVessel mechanicsPolymers IIIPolymer scaffoldsBiodegradable scaffoldsTissue engineeringPolymeric materialsDegradation characteristicsMatrix-rich tissuesSynthetic polymersPolymer IPolymer IIPolymer fragmentsAqueous conditionsPolymersPotential applicationsSimilar degradation profilesMechanics
2010
Intracoronary administration of paclitaxel nanoparticles during percutaneous coronary intervention for intimal hyperplasia suppression after bare-metal stent implantation
Chamié D, Abizaid A, Costa J, Feres F, Gama G, Belzares O, Staico R, Mattos L, Costa R, Siqueira D, Abizaid A, Chaves Á, Centemero M, Tanajura L, Sousa A, Sousa J. Intracoronary administration of paclitaxel nanoparticles during percutaneous coronary intervention for intimal hyperplasia suppression after bare-metal stent implantation. Journal Of Transcatheter Interventions 2010, 18: 140-150. DOI: 10.1590/s2179-83972010000200007.Peer-Reviewed Original ResearchBare-metal stent implantationPercutaneous coronary interventionStent implantationABI-007Neointimal hyperplasiaFollow-upCoronary interventionIntravascular ultrasoundAdverse toxic eventsSuppression of neointimal hyperplasiaAlbumin-bound paclitaxelLeft anterior descending arteryNeointimal volume obstructionStent implantation methodAnterior descending arteryTissue formationLong-term safetySignificant vascular remodelingSynthetic polymersSix-month follow-upIntravascular ultrasound assessmentDecreased neointimal hyperplasiaPaclitaxel nanoparticlesBare-metal stentsDrug-eluting stents
2009
Comparação da resposta vascular entre stents liberadores de sirolimus com diferentes doses e formas de eluição: análise com ultrassom intracoronário
Maia F, Chamié D, Costa J, Feres F, Abizaid A, Abizaid A, Costa R, Siqueira D, Staico R, Mattos L, Tanajura L, Centemero M, Chaves Á, Sousa A, Sousa J. Comparação da resposta vascular entre stents liberadores de sirolimus com diferentes doses e formas de eluição: análise com ultrassom intracoronário. Journal Of Transcatheter Interventions 2009, 17: 320-326. DOI: 10.1590/s2179-83972009000300008.Peer-Reviewed Original ResearchPercutaneous coronary interventionVascular remodelingPositive vascular remodelingSirolimus doseDrug-eluting stent implantationThrombosis risk factorsModerate cardiovascular riskDrug-eluting stentsLocal toxicityMonths followupCardiovascular riskSynthetic polymersGroup 2Pattern of elutionGroup 1High dosesStent implantationGroup 3Vascular eventsCoronary interventionRisk factorsAnti-proliferative agentsLuminal lossIVUS analysisDose
2002
Design of “Smart” polymers that can direct intracellular drug delivery
Hoffman A, Stayton P, Press O, Murthy N, Lackey C, Cheung C, Black F, Campbell J, Fausto N, Kyriakides T, Bornstein P. Design of “Smart” polymers that can direct intracellular drug delivery. Polymers For Advanced Technologies 2002, 13: 992-999. DOI: 10.1002/pat.232.Peer-Reviewed Original ResearchPH-sensitive polymerTypes of polymersEndosomal escapeBiomolecular drugsSynthetic polymersPolymeric biomaterialsBiological moleculesPeptide unitsPolymersBiomimetic propertiesEnvironmental signalsEndosomal membranesIntracellular traffickingMolecular mechanismsProtein coatGenetic materialBiological systemsEndosomesViral coatBondsAcidic pHSpecific peptidesInteresting modelLysosomal enzymesTrafficking
2001
Bioinspired polymers that control intracellular drug delivery
Hoffman A, Stayton P, Press O, Murthy N, Lackey C, Cheung C, Black F, Campbell J, Fausto N, Kyriakides T, Bornstein P. Bioinspired polymers that control intracellular drug delivery. Biotechnology And Bioprocess Engineering 2001, 6: 205-212. DOI: 10.1007/bf02931981.Peer-Reviewed Original ResearchPH-sensitive polymerIntracellular drug deliveryBioinspired polymersBiomimetic polymersBiomolecular drugsSynthetic polymersPolymeric biomaterialsBiological moleculesEnvironmental signalsPeptide unitsDrug deliveryPolymersEndosomal membranesBiomimetic propertiesMolecular mechanismsProtein coatViral coatEndosomal escapeBiological systemsInteresting modelSpecific peptidesEndosomesLysosomal enzymesCytoplasmPeptides
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