2021
Excess extracellular K+ causes inner hair cell ribbon synapse degeneration
Zhao H, Zhu Y, Liu L. Excess extracellular K+ causes inner hair cell ribbon synapse degeneration. Communications Biology 2021, 4: 24. PMID: 33398038, PMCID: PMC7782724, DOI: 10.1038/s42003-020-01532-w.Peer-Reviewed Original ResearchConceptsCochlear synaptopathySynapse degenerationRibbon synapsesNoise exposureNoise-induced cochlear synaptopathyInner hair cell ribbon synapsesIHC ribbon synapsesGlutamate receptor agonistsBK channel blockersHair cell ribbon synapsesReceptor agonistFirst synapseChannel blockersHearing lossIHC ribbonsHearing disordersDegenerationBK channelsPotential targetSynaptopathyAuditory systemSynapsesExposureSwellingExcitotoxicity
2015
The Role of Cell Volume in the Dynamics of Seizure, Spreading Depression, and Anoxic Depolarization
Ullah G, Wei Y, Dahlem M, Wechselberger M, Schiff S. The Role of Cell Volume in the Dynamics of Seizure, Spreading Depression, and Anoxic Depolarization. PLOS Computational Biology 2015, 11: e1004414. PMID: 26273829, PMCID: PMC4537206, DOI: 10.1371/journal.pcbi.1004414.Peer-Reviewed Original ResearchConceptsAnoxic depolarizationCell swellingDynamics of seizuresGlial KNeuroprotective roleSpreading DepressionEpileptic seizuresSeizuresPhysiological ceilingDepression statePathological activityCell volumeNeuronal dynamicsDepressionPathological statesSeparate seizuresIntervention strategiesNeuron membraneDepolarizationUse of volumeNeuronal behaviorOxygen homeostasisOxygen supplyCells swellSwelling
1994
A volume-activated taurine channel in skate hepatocytes: membrane polarity and role of intracellular ATP
Ballatori N, Simmons T, Boyer J. A volume-activated taurine channel in skate hepatocytes: membrane polarity and role of intracellular ATP. American Journal Of Physiology 1994, 267: g285-g291. PMID: 7521136, DOI: 10.1152/ajpgi.1994.267.2.g285.Peer-Reviewed Original ResearchConceptsCell swellingSkate hepatocytesIntracellular ATPExtracellular taurine concentrationMetabolic inhibitorsSinusoidal circulationHypotonic stimuliTaurine concentrationsTaurine effluxTaurine uptakeIndependent uptakeTaurine channelSkate liverEfflux mechanismTaurineLiverHepatocytesInhibitorsEffluxBasolateral membraneOsmolyte taurineSwellingAntimycin ADisulfonic acidTransport inhibitors
1981
688 PERIORBITAL AND ORBITAL CELLULITIS-A REAPPRAISAL
Shapiro E, Wald E, Bronzanski B, Michaels R. 688 PERIORBITAL AND ORBITAL CELLULITIS-A REAPPRAISAL. Pediatric Research 1981, 15: 557-557. DOI: 10.1203/00006450-198104001-00711.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPeriorbital swellingPeriorbital cellulitisConcurrent upper respiratory infectionUpper respiratory infectionDistinct clinical entityEar HospitalRespiratory infectionsAppropriate therapyBacterial cellulitisRadiographic evidenceClinical entityVenous congestionPositive bloodBony marginsTissue aspiratesCellulitisCareful differentiationSoft tissueSinusitisHibSinusRadiographsSwellingImportant differencesBacteremia
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