2021
Clinical Deployment of Explainable Artificial Intelligence of SPECT for Diagnosis of Coronary Artery Disease
Otaki Y, Singh A, Kavanagh P, Miller RJH, Parekh T, Tamarappoo BK, Sharir T, Einstein AJ, Fish MB, Ruddy TD, Kaufmann PA, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Cadet S, Liang JX, Dey D, Berman DS, Slomka PJ. Clinical Deployment of Explainable Artificial Intelligence of SPECT for Diagnosis of Coronary Artery Disease. JACC Cardiovascular Imaging 2021, 15: 1091-1102. PMID: 34274267, PMCID: PMC9020794, DOI: 10.1016/j.jcmg.2021.04.030.Peer-Reviewed Original ResearchConceptsTotal perfusion deficitMyocardial perfusion imagingStandard clinical softwareStress total perfusion deficitObstructive CADTomography myocardial perfusion imagingSPECT myocardial perfusion imagingStress myocardial perfusionCoronary artery diseaseReceiver-operating characteristic curveInvasive coronary angiographyClinical softwareReader diagnosisSingle photon emissionTypical clinical workflowArtery diseaseCoronary angiographyPerfusion deficitsDiagnostic findingsMyocardial perfusionPerfusion imagingVentricular volumeStandard clinical workstationPatientsDiagnostic accuracy
2012
Evaluation of Molecular Breast Imaging in Women Undergoing Myocardial Perfusion Imaging with Tc-99m Sestamibi
Hruska CB, Rhodes DJ, Collins DA, Tortorelli CL, Askew JW, O'Connor MK. Evaluation of Molecular Breast Imaging in Women Undergoing Myocardial Perfusion Imaging with Tc-99m Sestamibi. Journal Of Women's Health 2012, 21: 730-738. PMID: 22404787, DOI: 10.1089/jwh.2011.3267.Peer-Reviewed Original ResearchConceptsMolecular breast imagingBreast diseaseBreast cancerDiagnostic yieldMyocardial perfusionHigh-risk benign breast lesionsMyocardial perfusion stress testingRecent negative mammogramStress myocardial perfusionHigh diagnostic yieldStress myocardial perfusion studyBenign breast lesionsNumber of cancersMyocardial perfusion studiesBreast imagingNew cancersRecent mammogramSestamibi injectionNegative mammogramUnnecessary workupPerfusion studiesBreast lesionsCancerIsotope injectionWomen
2009
Rationale and design of a randomized controlled trial comparing stress myocardial perfusion imaging with coronary CT angiography as the initial imaging study for intermediate-risk patients admitted with chest pain
Levsky J, Travin M, Spevack D, Menegus M, Huang P, Goldberg Y, Clark E, Banoth P, Freeman K, Tobin J, Haramati L. Rationale and design of a randomized controlled trial comparing stress myocardial perfusion imaging with coronary CT angiography as the initial imaging study for intermediate-risk patients admitted with chest pain. Journal Of Cardiovascular Computed Tomography 2009, 3: 264-271. PMID: 19577217, DOI: 10.1016/j.jcct.2009.05.006.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseMyocardial perfusion imagingIntermediate-risk patientsChest painMajor adverse cardiovascular eventsRadionuclide myocardial perfusion imagingIntermediate-risk characteristicsSubsequent coronary revascularizationAdverse cardiovascular eventsEvaluation of patientsStress myocardial perfusionAcute myocardial infarctionClinical outcome endpointsInitial imaging studyNoninvasive cardiac imagingCoronary CT angiographyEvidence-based medicineTerms of outcomesCardiovascular eventsCoronary revascularizationHospital stayRenal dysfunctionSubsequent hospitalizationSecondary outcomesArtery disease
2008
CT angiography for evaluation of coronary artery disease in inner-city outpatients: an initial prospective comparison with stress myocardial perfusion imaging
Haramati L, Levsky J, Jain V, Altman E, Spindola-Franco H, Bobra S, Doddamani S, Travin M. CT angiography for evaluation of coronary artery disease in inner-city outpatients: an initial prospective comparison with stress myocardial perfusion imaging. The International Journal Of Cardiovascular Imaging 2008, 25: 303-313. PMID: 18979224, DOI: 10.1007/s10554-008-9382-5.Peer-Reviewed Original ResearchMeSH KeywordsContrast MediaCoronary AngiographyCoronary Artery DiseaseFemaleHumansLogistic ModelsMaleMiddle AgedOutpatientsPredictive Value of TestsProspective StudiesRadiographic Image Interpretation, Computer-AssistedRadiopharmaceuticalsSensitivity and SpecificityStatistics, NonparametricTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedUrban PopulationConceptsCT coronary angiographyCoronary artery diseaseNegative predictive valuePositive predictive valueInner-city outpatientsPredictive valueArtery diseaseCoronary angiographyMyocardial perfusionStress SPECT myocardial perfusionHigh negative predictive valueSubsequent cardiac catheterizationStress myocardial perfusionEvaluation of CADSPECT myocardial perfusionHIPAA-compliant studyPositive SPECTCardiac catheterizationClinical endpointsOutpatient populationPatient outcomesPerfusion defectsProspective comparisonCT angiographyMore homogenous groups
1996
Prognostic value of noninvasive testing one year after orthotopic cardiac transplantation
Verhoeven P, Lee F, Ramahi T, Franco K, de Leon C, Amatruda J, Gorham N, Mattera J, Wackers F. Prognostic value of noninvasive testing one year after orthotopic cardiac transplantation. Journal Of The American College Of Cardiology 1996, 28: 183-189. PMID: 8752812, DOI: 10.1016/0735-1097(96)00094-0.Peer-Reviewed Original ResearchConceptsCoronary artery vasculopathyOrthotopic cardiac transplantationCardiac transplantationEquilibrium radionuclide angiographyPrognostic valueRadionuclide angiographyClinical variablesNoninvasive testingHuman leukocyte antigen mismatchesStress thallium-201 imagingThallium-201 myocardial perfusion imagingConsecutive transplant recipientsRoutine noninvasive testingStress myocardial imagingCold ischemic timeStress myocardial perfusionThallium-201 imagingTwo-dimensional echocardiographyNoninvasive diagnostic testingMyocardial perfusion imagingOnly significant predictorAntigen mismatchesLate deathsTransplant recipientsIschemic time
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