2020
Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus aureus Bacteremia.
Corl K, Zeba F, Caffrey A, Hermenau M, Lopes V, Phillips G, Merchant R, Levy M, LaPlante K. Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus aureus Bacteremia. Critical Care Medicine 2020, 48: 525-532. PMID: 32205599, DOI: 10.1097/ccm.0000000000004212.Peer-Reviewed Original ResearchConceptsS. aureus bacteremiaStaphylococcus aureus bacteremiaSeptic shock patientsSeptic shockAntibiotic administrationShock patientsMethicillin-sensitive S. aureus bacteremiaMethicillin-resistant S. aureusThirty-day mortalityTiming of antibioticsAssociated with mortalityVeterans Affairs Health SystemThirty-dayRetrospective analysisBacteremiaEmergency department presentationsMultivariate analysisOdds ratioPatientsEmergency departmentAntibioticsMortalityAdministrationOddsHealth system
2019
Lack of correlation of virulence gene profiles of Staphylococcus aureus bacteremia isolates with mortality
Park K, Greenwood-Quaintance K, Cunningham S, Rajagopalan G, Chia N, Jeraldo P, Mandrekar J, Patel R. Lack of correlation of virulence gene profiles of Staphylococcus aureus bacteremia isolates with mortality. Microbial Pathogenesis 2019, 133: 103543. PMID: 31102653, DOI: 10.1016/j.micpath.2019.103543.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnimalsBacteremiaBacterial AdhesionBase SequenceCell ProliferationDrug Resistance, BacterialFemaleHLA-DR3 AntigenHumansImmune EvasionMaleMethicillin-Resistant Staphylococcus aureusMiceMice, TransgenicMiddle AgedMinnesotaPolymerase Chain ReactionStaphylococcal InfectionsStaphylococcus aureusSuperantigensVirulenceVirulence FactorsConceptsMethicillin-susceptible S. aureusS. aureus bacteremiaAureus bacteremiaMedical CenterHLA-DR3 transgenic miceStaphylococcus aureus bacteremiaMinnesota Medical CenterLarge medical centerImmune evasion genesVirulence genesVirulence gene profilesNumber of deathsClinical dataClinical valueTransgenic miceClinical practiceIndividual PCR assaysWhole-genome sequencing analysisMortalitySAg genesSurvivorsLack of correlationBacteremiaWGS analysisFunctional assays
2009
High Levels of mecA DNA Detected by a Quantitative Real-Time PCR Assay Are Associated with Mortality in Patients with Methicillin-Resistant Staphylococcus aureus Bacteremia
Ho Y, Chang S, Lin S, Wang W. High Levels of mecA DNA Detected by a Quantitative Real-Time PCR Assay Are Associated with Mortality in Patients with Methicillin-Resistant Staphylococcus aureus Bacteremia. Journal Of Clinical Microbiology 2009, 47: 2361-2361. PMCID: PMC2708482, DOI: 10.1128/jcm.00884-09.Peer-Reviewed Original Research
2008
LINEZOLID-INDUCED REVERSIBLE BICYTOPENIA IN A 4-YEAR-OLD BOY WITH METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS BACTEREMIA
Tavil B, Balci Y, Yıldırım I, Tavil Y, Secmeer G, Ceyhan M, Tuncer M. LINEZOLID-INDUCED REVERSIBLE BICYTOPENIA IN A 4-YEAR-OLD BOY WITH METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS BACTEREMIA. Pediatric Hematology And Oncology 2008, 25: 67-71. PMID: 18231956, DOI: 10.1080/08880010701703628.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusWhite blood cell countLinezolid therapyPlatelet countBlood culturesMethicillin-resistant Staphylococcus aureus bacteremiaDiagnosis of tetralogyUnnecessary laboratory investigationsStaphylococcus aureus bacteremiaAcute phase reactantsBlood cell countProgressive bicytopeniaAureus bacteremiaHemoglobin levelsInfective endocarditisPhase reactantsSide effectsCell countGeneral conditionTherapyOld boyBicytopeniaCytopeniasStaphylococcus aureusLinezolid
2006
Impact of Routine Intensive Care Unit Surveillance Cultures and Resultant Barrier Precautions on Hospital-Wide Methicillin-Resistant Staphylococcus aureus Bacteremia
Huang SS, Yokoe DS, Hinrichsen VL, Spurchise LS, Datta R, Miroshnik I, Platt R. Impact of Routine Intensive Care Unit Surveillance Cultures and Resultant Barrier Precautions on Hospital-Wide Methicillin-Resistant Staphylococcus aureus Bacteremia. Clinical Infectious Diseases 2006, 43: 971-978. PMID: 16983607, DOI: 10.1086/507636.Peer-Reviewed Original ResearchConceptsIntensive care unitContact isolation precautionsMRSA bacteremiaStaphylococcus aureus bacteremiaInfection control interventionsIsolation precautionsSurveillance culturesBarrier precautionsAureus bacteremiaIncidence densityHealth care-associated methicillin-resistant Staphylococcus aureus (MRSA) infectionsMethicillin-susceptible Staphylococcus aureus bacteremiaMethicillin-resistant Staphylococcus aureus (MRSA) infectionsControl interventionsMaximal sterile barrier precautionsResistant Staphylococcus aureus BacteremiaCentral venous catheter placementAlcohol-based hand rubHospital-wide reductionVenous catheter placementHand hygiene campaignRoutine surveillance culturesStaphylococcus aureus infectionInterrupted time series designBacteremia rates
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