2021
Polygenic scores for smoking and educational attainment have independent influences on academic success and adjustment in adolescence and educational attainment in adulthood
Hicks B, Clark D, Deak J, Schaefer J, Liu M, Jang S, Durbin C, Johnson W, Wilson S, Iacono W, McGue M, Vrieze S. Polygenic scores for smoking and educational attainment have independent influences on academic success and adjustment in adolescence and educational attainment in adulthood. PLOS ONE 2021, 16: e0255348. PMID: 34403414, PMCID: PMC8370636, DOI: 10.1371/journal.pone.0255348.Peer-Reviewed Original ResearchConceptsEducational attainment polygenic scoreSmoking PGSAcademic adjustmentPolygenic scoresAcademic variablesSignificant incremental associationsAge 14Minnesota Twin Family StudyGenetic influencesGeneral behavioral disinhibitionNon-cognitive traitsEducation polygenic scoreEducational attainmentTwin Family StudyAcademic motivationBehavioral disinhibitionDifferent genetic influencesDistinct genetic influencesPredictors of gradeIncremental associationAcademic successAdolescenceAge 11Educational successAdulthoodBehavioral Variant Frontotemporal Dementia: Diagnosis and Treatment Interventions
Balachandran S, Matlock E, Conroy M, Lane C. Behavioral Variant Frontotemporal Dementia: Diagnosis and Treatment Interventions. Current Geriatrics Reports 2021, 10: 101-107. DOI: 10.1007/s13670-021-00360-y.Peer-Reviewed Original ResearchVariant frontotemporal dementiaFrontotemporal dementiaCommon dementia syndromesCornerstone of treatmentNon-pharmacologic interventionsNon-pharmacologic managementCurrent pharmacologic therapiesBehavioral variant frontotemporal dementiaPrimary psychiatric illnessProgressive neurodegenerative disorderClinical research stagePharmacologic therapyDiagnostic workupDementia syndromesPsychiatric illnessTreatment interventionsCaregiver supportCholinesterase inhibitorsCertain symptomsReviewThe diagnosisBrain circuitsNeurodegenerative disordersEmotional bluntingDementiaBehavioral disinhibition
2018
From aggression to autism: new perspectives on the behavioral sequelae of monoamine oxidase deficiency
Bortolato M, Floris G, Shih J. From aggression to autism: new perspectives on the behavioral sequelae of monoamine oxidase deficiency. Journal Of Neural Transmission 2018, 125: 1589-1599. PMID: 29748850, PMCID: PMC6215718, DOI: 10.1007/s00702-018-1888-y.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderMAOA deficiencyBrunner syndromeBehavioral regulationMonoamine oxidaseCore symptoms of autism spectrum disorderMAOA knockout miceSymptoms of autism spectrum disorderLevels of intermale aggressionLow MAO-B activitySpectrum of neurodevelopmental problemsMetabolism of monoamine neurotransmittersImpulse-control problemsRisk-taking responsesMAO-B activityBehavioral disinhibitionPsychopathological featuresAntisocial conductCore symptomsAntisocial behaviorBehavioral sequelaeAggressive conductBehavioral phenotypesIntermale aggressionMonoamine neurotransmitters
2013
Factors Predicting Smoking in a Laboratory-Based Smoking-Choice Task
Bold KW, Yoon H, Chapman GB, McCarthy DE. Factors Predicting Smoking in a Laboratory-Based Smoking-Choice Task. Experimental And Clinical Psychopharmacology 2013, 21: 133-143. PMID: 23421357, PMCID: PMC3624971, DOI: 10.1037/a0031559.Peer-Reviewed Original ResearchConceptsGreater nicotine dependenceNicotine dependenceFirst puffRelapse risk factorsLow distress toleranceMedian timeMore cigarettesSmoking choicesRisk factorsSmoking cuesCessation attemptsIntensive smokingDistress toleranceMore puffsSurvival analysisNicotine deprivationSmoking lapseCigarettesBehavioral disinhibitionSmokingHigh impulsivityMinCurrent understandingParticipantsSmokers
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