1989
Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.
Lidow M, Goldman-Rakic P, Rakic P, Innis R. Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 6412-6416. PMID: 2548214, PMCID: PMC297850, DOI: 10.1073/pnas.86.16.6412.Peer-Reviewed Original ResearchConceptsDopamine D2 receptorsD2 receptorsD2 sitesDopamine D1 receptorsNeostriatum of ratsD2-selective antagonistRostral-caudal gradientCerebral cortexDopaminergic innervationD1 receptorsDopamine levelsDopamine receptorsPharmacological characterizationRat cortexSelective antagonistOccipital cortexPharmacological profileCognitive functionCortexReceptorsNeostriatumApparent involvementPresent studySaturable mannerMonkeys
1986
[3H]bumetanide binding to duck red cells. Correlation with inhibition of (Na + K + 2Cl) co-transport.
Haas M, Forbush B. [3H]bumetanide binding to duck red cells. Correlation with inhibition of (Na + K + 2Cl) co-transport. Journal Of Biological Chemistry 1986, 261: 8434-8441. PMID: 3013852, DOI: 10.1016/s0021-9258(19)83931-5.Peer-Reviewed Original ResearchConceptsDuck red cellsExtracellular sodiumRed cellsCo-transportDog kidney outer medullaBinding of [3H]bumetanideConcentration of extracellular sodiumIncreased extracellular sodiumPresence of norepinephrineCo-transport systemBumetanide inhibitionKidney outer medullaOuter medullaBiphasic effectInhibition of influxCell shrinkageHalf-maximalSaturable bindingBumetanideInhibit bindingCell typesSaturable mannerNorepinephrineInfluxBinding to membranes
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