2020
A Dense Fibrillar Collagen Scaffold Differentially Modulates Secretory Function of iPSC-Derived Vascular Smooth Muscle Cells to Promote Wound Healing
Dash BC, Setia O, Gorecka J, Peyvandi H, Duan K, Lopes L, Nie J, Berthiaume F, Dardik A, Hsia HC. A Dense Fibrillar Collagen Scaffold Differentially Modulates Secretory Function of iPSC-Derived Vascular Smooth Muscle Cells to Promote Wound Healing. Cells 2020, 9: 966. PMID: 32295218, PMCID: PMC7226960, DOI: 10.3390/cells9040966.Peer-Reviewed Original ResearchConceptsVascular smooth muscle cellsSmooth muscle cellsSecretory functionHuman-induced pluripotent stem cellsParacrine secretionMuscle cellsCollagen fibrillar densitiesSecretory factorsVascular regenerationWound healingTissue-engineered vascular graftsHealingVascular graftsStem cellsPluripotent stem cellsCollagen scaffoldsScaffold propertiesScaffold materialsCellsPromising strategyDisease modelingFibrillar densityRegenerative wound healingCytokinesGraft
2014
A hypothesis-driven parametric study of effects of polymeric scaffold properties on tissue engineered neovessel formation
Miller KS, Khosravi R, Breuer CK, Humphrey JD. A hypothesis-driven parametric study of effects of polymeric scaffold properties on tissue engineered neovessel formation. Acta Biomaterialia 2014, 11: 283-294. PMID: 25288519, PMCID: PMC4256111, DOI: 10.1016/j.actbio.2014.09.046.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood VesselsCompressive StrengthComputer SimulationComputer-Aided DesignElastic ModulusEndothelial CellsEquipment DesignEquipment Failure AnalysisHardnessHumansMaterials TestingModels, ChemicalNeovascularization, PhysiologicPolymersTensile StrengthTissue EngineeringTissue ScaffoldsConceptsScaffold parametersMaterial propertiesScaffold structureParametric studyFibrous scaffoldsScaffold propertiesBurst pressureConstitutive relationsSuture retentionNeotissue developmentTissue engineeringMechanobiological cuesNeovessel developmentFiber diameterNew modeling frameworkExperimental search spaceVascular graftsOptimal combinationPropertiesKey propertiesModeling frameworkParametersNumber of parametersComputational modelNative properties
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply