2019
209-OR: ADA Presidents' Select Abstract: Type 1 Diabetes and the Developing Brain—A Longitudinal Study of Brain Growth by the Diabetes Research in Children Network (DirecNet)
ARBELAEZ A, O’DONOGHUE S, MAURAS N, BUCKINGHAM B, WHITE N, WEINZIMER S, AYE T, TSALIKIAN E, WILSON D, TAMBORLANE W, TANSEY M, CATO A, HERSHEY T, FOX L, ENGLERT K, REISS A. 209-OR: ADA Presidents' Select Abstract: Type 1 Diabetes and the Developing Brain—A Longitudinal Study of Brain Growth by the Diabetes Research in Children Network (DirecNet). Diabetes 2019, 68 DOI: 10.2337/db19-209-or.Peer-Reviewed Original ResearchDiabetes careNondiabetic controlsVoxel-based morphometryMedtronic MiniMedWhite matterSubcortical GMSpouse/partnerEarly-onset type 1 diabetesEunice Kennedy Shriver National InstituteAge-matched nondiabetic controlsEarly-onset T1DTime of diagnosisWorse glycemic controlType 1 diabetesEffects of T1DBasal ganglia regionsAdvisory PanelRapid brain maturationWhite matter areasEli LillyGray matter volumeGray matter regionsTakeda Pharmaceutical Company LimitedGlycemic exposureT1D childrenInsight Into the Emerging Role of Striatal Neurotransmitters in the Pathophysiology of Parkinson’s Disease and Huntington’s Disease: A Review
Jamwal S, Kumar P. Insight Into the Emerging Role of Striatal Neurotransmitters in the Pathophysiology of Parkinson’s Disease and Huntington’s Disease: A Review. Current Neuropharmacology 2019, 17: 165-175. PMID: 29512464, PMCID: PMC6343208, DOI: 10.2174/1570159x16666180302115032.Peer-Reviewed Original ResearchConceptsParkinson's diseaseHuntington's diseaseStriatal neurotransmittersNeuronal deathNeurotransmitter levelsAltered neurotransmitters levelBasal ganglia regionsExcitotoxic neuronal deathNeurotransmitter alterationsBrain dopaminePathophysiological basisBasal gangliaGanglia regionsMovement disordersPreclinical studiesReceptor densitySpecific drugsCoordinated body movementsDiseaseNeurotransmittersAltered levelsOxidative stressExact mechanismMitochondrial dysfunctionImportant neurotransmitter
2003
Functional consequences of the repeated administration of Δ9-tetrahydrocannabinol in the rat
Whitlow C, Freedland C, Porrino L. Functional consequences of the repeated administration of Δ9-tetrahydrocannabinol in the rat. Drug And Alcohol Dependence 2003, 71: 169-177. PMID: 12927655, DOI: 10.1016/s0376-8716(03)00135-2.Peer-Reviewed Original ResearchConceptsAdministration of THCDevelopment of toleranceTHC exposureLocomotor activityBrain regionsAcute administration of THCPatterns of functional activationCannabinoid agonist treatmentEffects of THCFunction of cannabinoid receptorsTreated with THCCerebral metabolic effectsBasal ganglia regionsAdministered THCSets of ratsNucleus accumbensTHC administrationBasolateral amygdalaCore body temperatureMediodorsal thalamusDelta(9)-tetrahydrocannabinolTHC treatmentLimbic areasCannabinoid receptorsDays of drug exposure
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