2016
The Steroidogenic Acute Regulatory Protein (StAR) Is Regulated by the H19/let-7 Axis
Men Y, Fan Y, Shen Y, Lu L, Kallen AN. The Steroidogenic Acute Regulatory Protein (StAR) Is Regulated by the H19/let-7 Axis. Endocrinology 2016, 158: 402-409. PMID: 27813675, PMCID: PMC5413078, DOI: 10.1210/en.2016-1340.Peer-Reviewed Original ResearchConceptsSteroidogenic acute regulatory proteinRegulatory proteinsAcute regulatory proteinPost-transcriptional levelRate-limiting stepMicroRNA let-7H19/letRegulation of reproductionMurine cell linesLet-7Overexpression of H19Long noncoding RNA H19Regulation of steroidogenesisCellular growthSpecific tissuesNovel mechanismMultiple rolesNovel targetRNA H19StAR expressionExpression variesCell linesRegulationH19Protein
2008
Cross-talk between estrogen and leptin signaling in the hypothalamus
Gao Q, Horvath TL. Cross-talk between estrogen and leptin signaling in the hypothalamus. AJP Endocrinology And Metabolism 2008, 294: e817-e826. PMID: 18334610, DOI: 10.1152/ajpendo.00733.2007.Peer-Reviewed Original ResearchConceptsAdipocyte-secreted hormone leptinGonadal steroid hormone estrogenAction of leptinMajor risk factorNeuroendocrine reproductive axisEnergy expenditureHalf of adultsSteroid hormone estrogenEnhanced food intakeFunction of estrogenEstrogen deficiencyRisk factorsHormone leptinCardiovascular diseaseHormone estrogenFood intakeBody fatReproductive axisLeptinEstrogenRegulation of reproductionEnergy homeostasisWeight gainEstrogen facilitatesNeuroendocrine processes
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