Haris Mirza, MD, PhD
Assistant Professor of PathologyCards
About
Research
Publications
Featured Publications
Immune Control of Oncogene Selection in the Colon.
Mirza H, Tschiatschek* B, Maqsood* M, Li X, Oh MH, Sefik E, Zhang F, Lau SF, Hashim S, Juric V, Tran F, Agrawal K, Blackburn N, Roulis M, Olaloye O, Konnikova L, Haase G, Kluger Y, Simons B, Corominas-Murtra B, Flavell R. Immune Control of Oncogene Selection in the Colon. 2026 DOI: 10.21203/rs.3.rs-8673399/v1.Peer-Reviewed Original Research
2025
Editorial: Advancements in translational models: bridging basic infection research and clinical applications.
Schmidtchen A, Nadeem A, Mirza H, Wallblom K, Raina DB, Shannon O, Petrlova J, Puthia M. Editorial: Advancements in translational models: bridging basic infection research and clinical applications. Front Med (Lausanne) 2025, 12: 1730195. PMID: 41341817, DOI: 10.3389/fmed.2025.1730195.Peer-Reviewed Original ResearchHumanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow
Sefik E, Philbrick W, Zhang F, Agrawal K, Van Lee B, Sam J, Karatepe K, Zheng Y, Liang K, Peng S, Mirza H, Rangavajhula A, Simon P, Arun N, Babu P, Eynon E, Chiorazzi M, Shan L, Halene S, Luo H, Rongvaux A, Kluger Y, Flavell R. Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2426546122. PMID: 40956886, PMCID: PMC12478129, DOI: 10.1073/pnas.2426546122.Peer-Reviewed Original Research
2023
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions
Kaffe E, Roulis M, Zhao J, Qu R, Sefik E, Mirza H, Zhou J, Zheng Y, Charkoftaki G, Vasiliou V, Vatner D, Mehal W, AlcHepNet, Kluger Y, Flavell R. Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions. Cell 2023, 186: 3793-3809.e26. PMID: 37562401, PMCID: PMC10544749, DOI: 10.1016/j.cell.2023.07.017.Peer-Reviewed Original ResearchIL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory
Micevic G, Daniels A, Flem-Karlsen K, Park K, Talty R, McGeary M, Mirza H, Blackburn H, Sefik E, Cheung J, Hornick N, Aizenbud L, Joshi N, Kluger H, Iwasaki A, Bosenberg M, Flavell R. IL-7R licenses a population of epigenetically poised memory CD8+ T cells with superior antitumor efficacy that are critical for melanoma memory. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2304319120. PMID: 37459511, PMCID: PMC10372654, DOI: 10.1073/pnas.2304319120.Peer-Reviewed Original Research
2022
Editorial: Methods and applications in inflammation pharmacology
Schmidtchen A, Mirza H, van der Plas M, Nadeem A, Puthia M. Editorial: Methods and applications in inflammation pharmacology. Frontiers In Pharmacology 2022, 13: 1108263. PMID: 36578538, PMCID: PMC9792174, DOI: 10.3389/fphar.2022.1108263.Commentaries, Editorials and LettersAn update on ductal plate malformations and fibropolycystic diseases of the liver
Mirza H, Besse W, Somlo S, Weinreb J, Kenney B, Jain D. An update on ductal plate malformations and fibropolycystic diseases of the liver. Human Pathology 2022, 132: 102-113. PMID: 35777701, DOI: 10.1016/j.humpath.2022.06.022.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsInflammasome activation in infected macrophages drives COVID-19 pathology
Sefik E, Qu R, Junqueira C, Kaffe E, Mirza H, Zhao J, Brewer JR, Han A, Steach HR, Israelow B, Blackburn HN, Velazquez SE, Chen YG, Halene S, Iwasaki A, Meffre E, Nussenzweig M, Lieberman J, Wilen CB, Kluger Y, Flavell RA. Inflammasome activation in infected macrophages drives COVID-19 pathology. Nature 2022, 606: 585-593. PMID: 35483404, PMCID: PMC9288243, DOI: 10.1038/s41586-022-04802-1.Peer-Reviewed Original Research
2021
A humanized mouse model of chronic COVID-19
Sefik E, Israelow B, Mirza H, Zhao J, Qu R, Kaffe E, Song E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen CB, Iwasaki A, Flavell RA. A humanized mouse model of chronic COVID-19. Nature Biotechnology 2021, 40: 906-920. PMID: 34921308, PMCID: PMC9203605, DOI: 10.1038/s41587-021-01155-4.Peer-Reviewed Original Research
2015
Mutations Affecting Keratin 10 Surface-Exposed Residues Highlight the Structural Basis of Phenotypic Variation in Epidermolytic Ichthyosis
Mirza H, Kumar A, Craiglow BG, Zhou J, Saraceni C, Torbeck R, Ragsdale B, Rehder P, Ranki A, Choate KA. Mutations Affecting Keratin 10 Surface-Exposed Residues Highlight the Structural Basis of Phenotypic Variation in Epidermolytic Ichthyosis. Journal Of Investigative Dermatology 2015, 135: 3041-3050. PMID: 26176760, DOI: 10.1038/jid.2015.284.Peer-Reviewed Original Research
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Maile Adams
Graduate student2025 - 2026Si Wong
Graduate student2025 - 2026Shahistha Jabeen Hashim
Graduate student2024 - 2026Miraal Maqsood
Graduate student2024 - 2025
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