2023
Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis
Mathis M, Janda A, Kheterpal S, Schonberger R, Pagani F, Engoren M, Mentz G, Shook D, Muehlschlegel J, Cassidy R, Clark D, Colquhoun D, Freundlich R, Jewell E. Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis. Anesthesiology 2023, 139: 122-141. PMID: 37094103, PMCID: PMC10524016, DOI: 10.1097/aln.0000000000004593.Peer-Reviewed Original ResearchConceptsInotrope useCardiac surgeryHome medicationsAdjusted median odds ratioPulmonary circulation disordersAdult cardiac surgeryMechanical circulatory supportMedian odds ratioMedical school affiliationHome inotropesInotrope infusionInotrope therapyInotropic therapyCardiopulmonary bypassHeart failureMulticenter cohortPrimary outcomeCirculatory supportBlack raceCirculation disordersOdds ratioCommunity hospitalObservational studySame patientPatients
2018
Quantification of Postmembrane Gaseous Microembolization During Venoarterial Extracorporeal Membrane Oxygenation
Jiao Y, Gipson KE, Bonde P, Mangi A, Hagberg R, Rosinski DJ, Gross JB, Schonberger RB. Quantification of Postmembrane Gaseous Microembolization During Venoarterial Extracorporeal Membrane Oxygenation. ASAIO Journal 2018, 64: 31-37. PMID: 28557862, DOI: 10.1097/mat.0000000000000598.Peer-Reviewed Original ResearchConceptsVenoarterial extracorporeal membrane oxygenationVA-ECMO patientsExtracorporeal membrane oxygenationGaseous microemboliVA-ECMOECMO patientsMembrane oxygenationCardiopulmonary bypassAdult VA-ECMO patientsExtracorporeal membrane oxygenation circuitEnd-organ dysfunctionInstitutional review board approvalRoutine patient careMembrane oxygenation circuitPatient care eventsPatient care activitiesReview board approvalOrgan dysfunctionEmbolic rateClinical eventsObservational studyIntravenous injectionEnd organsGME volumeBoard approval
2017
A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia
Chen EY, Sukumar N, Dai F, Akhtar S, Schonberger RB. A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 666-671. PMID: 29277298, PMCID: PMC5766429, DOI: 10.1053/j.jvca.2017.07.009.Peer-Reviewed Original ResearchConceptsTransfemoral aortic valve replacementMonitored Anesthesia CareAortic valve replacementGeneral anesthesiaValve replacementAge incrementsMedication dose adjustmentUse of dexmedetomidineRetrospective observational studyType of sedationTertiary teaching hospitalHospital lengthPostoperative deliriumTAVR patientsDose adjustmentConscious sedationAnesthesia careCare drugsPossible differential effectsTeaching hospitalObservational studyAnesthetic agentsDose reductionDrug dosingPilot analysis
2016
A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients?
Akhtar S, Heng J, Dai F, Schonberger RB, Burg MM. A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients? Drugs & Aging 2016, 33: 737-746. PMID: 27581549, DOI: 10.1007/s40266-016-0394-x.Peer-Reviewed Original ResearchConceptsDoses of fentanylOlder patientsFemale patientsInduction dosesGeneral anesthesiaObservational studyTertiary care academic hospitalElderly surgical patientsIncidence of hypotensionDose of propofolRetrospective observational studyOld female patientIntravenous anesthetic agentPost-induction hypotensionAge-associated differencesQuality improvement effortsResultsOlder patientsVasopressor therapyElderly patientsSurgical patientsYounger patientsBlood pressureHemodynamic outcomesASA-PSStudy designWe
2012
Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting Metoprolol
Schonberger RB, Brandt C, Feinleib J, Dai F, Burg MM. Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting Metoprolol. Journal Of Cardiothoracic And Vascular Anesthesia 2012, 27: 298-304. PMID: 22889605, PMCID: PMC3557658, DOI: 10.1053/j.jvca.2012.06.021.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAmbulatory Surgical ProceduresAntihypertensive AgentsAtenololChemistry, PharmaceuticalCohort StudiesConfidence IntervalsDelayed-Action PreparationsFemaleHeart RateHemodynamicsHumansLeast-Squares AnalysisLinear ModelsMaleMetoprololMiddle AgedOutpatientsPatient CompliancePropensity ScoreTreatment OutcomeConceptsBeats/minTwice-daily dosing regimensAmbulatory surgical patientsHeart rateSurgical patientsDosing regimensMetoprolol formulationsPrimary care visitsDay of surgeryRetrospective observational studyVeterans Administration HospitalGeneral linear modelHeart rate differencesΒ-blocker typeCare visitsAdministration HospitalObservational studyPatientsMetoprololAtenololMetoprolol succinateRegimensDaysLow dayMinBeta-Blocker Withdrawal Among Patients Presenting for Surgery from Home
Schonberger RB, Lukens CL, Turkoglu OD, Feinleib JL, Haspel KL, Burg MM. Beta-Blocker Withdrawal Among Patients Presenting for Surgery from Home. Journal Of Cardiothoracic And Vascular Anesthesia 2012, 26: 1029-1033. PMID: 22418043, PMCID: PMC3419315, DOI: 10.1053/j.jvca.2012.01.024.Peer-Reviewed Original ResearchConceptsDay of surgeryΒ-blocker therapyLong-term β-blocker therapyHeart rateΒ-blockersVital signsFuture quality improvement initiativesBeta-blocker withdrawalΒ-blocker withdrawalProspective observational studyVeterans Administration HospitalQuality improvement initiativesSelf-reported complianceAdherent subjectsPreoperative clinicComorbidity dataPatient noncompliancePreoperative visitPrimary careMedical recordsAdministration HospitalObservational studyMedication instructionsPatient understandingOutcome data