2024
Allergic Contact Dermatitis: A Model of Inflammatory Itch and Pain in Human and Mouse
LaMotte R. Allergic Contact Dermatitis: A Model of Inflammatory Itch and Pain in Human and Mouse. 2024, 23-32. DOI: 10.1007/978-981-99-8921-8_2.Peer-Reviewed Original ResearchSquaric acid dibutyl esterAllergic contact dermatitisPersistent itchingPathogenesis of allergic contact dermatitisPain-like behaviorsMechanically evoked itchMechanisms of itchPeripheral neural mechanismsClinically significant problemReceptor CXCR3Excitatory responsesIP-10Chemokine CXCL10In vivo recordingsCutaneous sitesLocal inflammationSpontaneous activityPruritic disordersAnimal modelsPainTopical applicationItchingItch disordersMiceTherapeutic target
2016
Allergic Contact Dermatitis: A Model of Inflammatory Itch and Pain in Human and Mouse
LaMotte RH. Allergic Contact Dermatitis: A Model of Inflammatory Itch and Pain in Human and Mouse. Advances In Experimental Medicine And Biology 2016, 904: 23-32. PMID: 26900060, PMCID: PMC4910628, DOI: 10.1007/978-94-017-7537-3_2.Peer-Reviewed Original ResearchConceptsAllergic contact dermatitisPersistent itchPathogenesis of ACDSquaric acid dibutyl esterPain-like behaviorsSmall-diameter neuronsPeripheral neural mechanismsPossible therapeutic targetInflammatory itchPruritic disordersCutaneous sitesChemokine CXCL10Excitatory responsesLocal inflammationReceptor CXCR3Contact dermatitisUnmyelinated axonsSpontaneous activityTherapeutic targetAnimal modelsPainSubsequent challengeTopical applicationItchMice