2022
Preoperative Management of Cardiovascular Medications: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement
Sahai SK, Balonov K, Bentov N, Bierle DMM, Browning LM, Cummings KC, Dougan BM, Maxwell M, Merli GJ, Oprea AD, Sweitzer B, Mauck KF, Urman RD. Preoperative Management of Cardiovascular Medications: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement. Mayo Clinic Proceedings 2022, 97: 1734-1751. PMID: 36058586, DOI: 10.1016/j.mayocp.2022.03.039.Peer-Reviewed Original ResearchConceptsCardiovascular medicationsPerioperative assessmentAntiarrhythmic agentsReceptor antagonistAngiotensin receptor neprilysin inhibitorQuality Improvement (SPAQI) Consensus StatementAngiotensin II receptor blockersClass I antiarrhythmic agentsClass III antiarrhythmic agentII receptor blockersClasses of medicationsEndothelin receptor antagonistsPotassium-sparing diureticsCalcium channel blockersΒ-adrenoceptor blockersAdrenergic receptor antagonistPhosphodiesterase-5 inhibitorsEvidence-based recommendationsSodium channel blockersPotassium channel openersSympatholytic medicationsReceptor blockersPerioperative managementHeart failureLoop diureticsPreoperative Management of Medications for Rheumatologic and HIV Diseases: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement
Russell LA, Craig C, Flores EK, Wainaina JN, Keshock M, Kasten MJ, Hepner DL, Edwards AF, Urman RD, Mauck KF, Oprea AD. Preoperative Management of Medications for Rheumatologic and HIV Diseases: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement. Mayo Clinic Proceedings 2022, 97: 1551-1571. PMID: 35933139, DOI: 10.1016/j.mayocp.2022.05.002.Peer-Reviewed Original ResearchConceptsPerioperative medication managementPerioperative assessmentConsensus statementPreoperative managementMedication managementQuality Improvement (SPAQI) Consensus StatementEvidence-based perioperative careAnti-inflammatory medicationsPerioperative medical managementInfectious disease specialistsLong-term medicationInternal medicine physiciansComplexity of patientsPreoperative optimizationHIV diseaseCommon medicationsPerioperative careMedical managementDisease specialistsClinical guidanceConsensus recommendationsSurgical proceduresMedicine physiciansMedicationsExpert consensusPostdural Puncture Headache—Risks and Current Treatment
Li H, Wang Y, Oprea AD, Li J. Postdural Puncture Headache—Risks and Current Treatment. Current Pain And Headache Reports 2022, 26: 441-452. PMID: 35353358, DOI: 10.1007/s11916-022-01041-x.Peer-Reviewed Original ResearchConceptsPostdural puncture headacheCurrent treatmentDevelopment of PDPHMild postdural puncture headacheSevere postdural puncture headacheSelf-limited headacheEpidural blood patchFirst-line treatmentLong-term complicationsTherapy of choiceDull achingHeadache riskPDPH patientsPharmacological managementConservative treatmentBlood patchConservative managementFrequent complicationNerve blockNeuraxial blockNeuraxial techniquesPuncture headacheBed restChronic headacheFemale sexPreoperative Management of Medications for Neurologic Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement
Oprea AD, Keshock MC, O'Glasser AY, Cummings KC, Edwards AF, Hunderfund AL, Urman RD, Mauck KF. Preoperative Management of Medications for Neurologic Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement. Mayo Clinic Proceedings 2022, 97: 375-396. PMID: 35120701, DOI: 10.1016/j.mayocp.2021.11.010.Peer-Reviewed Original ResearchConceptsPreoperative managementPerioperative assessmentNeurologic disordersQuality Improvement (SPAQI) Consensus StatementEvidence-based recommendationsPerioperative medicationsDiseases SocietyPerioperative cliniciansSocietal guidelinesConsensus statementNeurologic diseaseConsensus recommendationsInvasive proceduresMedicationsDrug substitutionIndividualized approachAnesthesia practicePerioperative medicineInternal medicineDisordersPatientsLaboratory testingMedicineManagementCliniciansPreoperative Management of Medications for Psychiatric Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement
Oprea AD, Keshock MC, O'Glasser AY, Cummings KC, Edwards AF, Zimbrean PC, Urman RD, Mauck KF. Preoperative Management of Medications for Psychiatric Diseases Society for Perioperative Assessment and Quality Improvement Consensus Statement. Mayo Clinic Proceedings 2022, 97: 397-416. PMID: 35120702, DOI: 10.1016/j.mayocp.2021.11.011.Peer-Reviewed Original ResearchConceptsPsychiatric medication managementPreoperative managementPerioperative assessmentMedication managementConsensus statementQuality Improvement (SPAQI) Consensus StatementAttention deficit hyperactivity disorder medicationsDay of surgeryRisk of relapseHyperactivity disorder medicationsCategories of drugsMedication classesPerioperative complicationsDiseases SocietyMost medicationsIndividual medicationsMood stabilizersPsychiatric medicationsConsensus recommendationsMedicationsDrug categoriesCertain drugsPatient carePsychiatric conditionsProcedure cancellations
2021
Perioperative thrombocytopenia
Lombard FW, Popescu WM, Oprea AD, Kertai MD. Perioperative thrombocytopenia. Current Opinion In Anaesthesiology 2021, 34: 335-344. PMID: 33935182, DOI: 10.1097/aco.0000000000000999.Peer-Reviewed Original ResearchConceptsPlatelet countThrombopoietin receptor agonistsRisk of bleedingProphylactic platelet transfusionsProthrombin complex concentrateRecombinant factor VIIGood quality evidenceThreshold platelet countIntravenous immunoglobulinPreoperative thrombocytopeniaAsymptomatic patientsPerioperative strategiesPerioperative managementSevere bleedingAntifibrinolytic agentsPlatelet transfusionsComplex concentrateQuality evidenceFibrinogen levelsReceptor agonistPerioperative thrombocytopeniaPlatelet functionThrombin generationIntraoperative alternativeFactor VIIEditorial: Perioperative medicine: a bridge (not) too far!
Oprea AD. Editorial: Perioperative medicine: a bridge (not) too far! Current Opinion In Anaesthesiology 2021, 34: 306-308. PMID: 33935178, DOI: 10.1097/aco.0000000000000995.Peer-Reviewed Original ResearchHumansPerioperative MedicineEndocrine emergencies in anesthesia
Fernandez-Robles C, Carr ZJ, Oprea AD. Endocrine emergencies in anesthesia. Current Opinion In Anaesthesiology 2021, 34: 326-334. PMID: 33935181, DOI: 10.1097/aco.0000000000000986.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEndocrine disordersPerioperative managementOral hyperglycemic agentsPerioperative fluid resuscitationPerioperative glycemic managementSafe perioperative managementCommon endocrine disorderPerioperative time periodNumber of patientsBetter operative outcomesInvasive surgical techniquesCarcinoid syndromeEndocrine emergencyAdverse eventsFluid resuscitationGlycemic managementOperative outcomesAvoidable complicationsMedical managementComplex patientsSurgical techniqueHyperglycemic agentOptimal managementOperating roomDisordersThe Electrophysiology Laboratory: Anesthetic Considerations and Staffing Models
Siegrist KK, Fernandez Robles C, Kertai MD, Oprea AD. The Electrophysiology Laboratory: Anesthetic Considerations and Staffing Models. Journal Of Cardiothoracic And Vascular Anesthesia 2021, 35: 2775-2783. PMID: 33773891, DOI: 10.1053/j.jvca.2021.02.050.Peer-Reviewed Original Research
2020
Nonoperating room anesthesia in different parts of the world.
Fernandez-Robles C, Oprea AD. Nonoperating room anesthesia in different parts of the world. Current Opinion In Anaesthesiology 2020, 33: 520-526. PMID: 32628399, DOI: 10.1097/aco.0000000000000886.Peer-Reviewed Original ResearchConceptsNonoperating room anesthesiaInvasive proceduresAnesthesia servicesRoom anesthesiaOperating room patientsProceduralist satisfactionSerious complicationsAnesthetic careRoom patientsEarly diagnosisOperating room locationsNumber of casesTreatment of diseasesPatientsOperating roomAnesthesiaPresent reviewCareComplicationsDiseaseDiagnosisDifferent partsPeriprocedural management of patients on oral anticoagulation: focus on regional anesthesia.
Li J, Oprea AD. Periprocedural management of patients on oral anticoagulation: focus on regional anesthesia. Polish Archives Of Internal Medicine 2020, 130: 1081-1092. PMID: 32491305, DOI: 10.20452/pamw.15416.Peer-Reviewed Original ResearchConceptsRegional anesthesia proceduresOral anticoagulantsAnesthesia proceduresPermanent neuronal damageBlood loss volumePeripheral nerve blocksOperating room proceduresNoncompressible areasOral anticoagulationPeriprocedural managementAnticoagulant medicationNeuronal damageNerve blockNeuraxial anesthesiaDeep plexusThrombotic riskCurrent guidelinesRegional anesthesiaLoss volumeRoom proceduresStandardized usePatientsAnesthesiaAnticoagulantsPatient anatomyUpdates in periprocedural management of direct oral anticoagulants.
Tao J, Oprea AD. Updates in periprocedural management of direct oral anticoagulants. Current Opinion In Anaesthesiology 2020, 33: 423-431. PMID: 32371643, DOI: 10.1097/aco.0000000000000873.Peer-Reviewed Original ResearchConceptsDirect oral anticoagulantsPeriprocedural managementOral anticoagulantsPrevalence of patientsDrug interruptionTrough levelsComplete clearanceProcedural riskPartial clearanceClinical riskAmerican CollegeElectrophysiology proceduresFavorable pharmacokineticsQuick onsetAnticoagulantsRiskClearanceDrugsReview detailsBleedingMedicationsManagementPatientsAntithromboticsAnesthesiologists
2019
Contemporary personalized β-blocker management in the perioperative setting
Oprea AD, Wang X, Sickeler R, Kertai MD. Contemporary personalized β-blocker management in the perioperative setting. Journal Of Anesthesia 2019, 34: 115-133. PMID: 31637510, DOI: 10.1007/s00540-019-02691-9.Peer-Reviewed Original ResearchConceptsPerioperative β-blocker useΒ-blocker useMajor postoperative cardiac eventsPost-acute myocardial infarctionCardiac adverse eventsPostoperative cardiac eventsSystolic heart failureBeta-adrenergic blockersLong-term treatmentCase-based reviewAdverse eventsCardiac eventsPerioperative periodPerioperative useCardiac surgeryHeart failureMyocardial infarctionPerioperative settingEarlier small-scale studiesTrialsEvaluation trialsPotential benefitsNoncardiacEarlier findingsInfarctionPeriprocedural Anticoagulation Management For Nonoperating Room Anesthesia Procedures: A Clinical Guide
Tao J, Oprea AD. Periprocedural Anticoagulation Management For Nonoperating Room Anesthesia Procedures: A Clinical Guide. Seminars In Cardiothoracic And Vascular Anesthesia 2019, 23: 352-368. PMID: 31431127, DOI: 10.1177/1089253219870627.Peer-Reviewed Original ResearchConceptsOral anticoagulantsChronic oral anticoagulationPeriprocedural anticoagulation managementRoom anesthesiaNonoperating room anesthesiaNon-operating room proceduresOral anticoagulationPeriprocedural managementAnticoagulation managementClinical guideTraditional surgeryNon-operating room anesthesiaSafe careRoom proceduresAnesthesiaAnticoagulantsRiskManagement optionsAnticoagulationPatientsSurgeryUnique challengesAnesthesiologistsPharmacokineticsManagementEnhanced Recovery After Lung Surgery: Fad or Fashion?
Oprea AD, Perrino AC, Popescu WM. Enhanced Recovery After Lung Surgery: Fad or Fashion? Journal Of Cardiothoracic And Vascular Anesthesia 2019, 33: 2445-2447. PMID: 31076304, DOI: 10.1053/j.jvca.2019.03.061.Peer-Reviewed Original Research
2018
Perioperative β-Adrenergic Blockade in Noncardiac and Cardiac Surgery: A Clinical Update
Oprea AD, Lombard FW, Kertai MD. Perioperative β-Adrenergic Blockade in Noncardiac and Cardiac Surgery: A Clinical Update. Journal Of Cardiothoracic And Vascular Anesthesia 2018, 33: 817-832. PMID: 29934209, DOI: 10.1053/j.jvca.2018.04.045.Peer-Reviewed Original Research
2017
Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study
Oprea AD, Del Rio JM, Cooter M, Green CL, Karhausen JA, Nailer P, Guinn NR, Podgoreanu MV, Stafford-Smith M, Schroder JN, Fontes ML, Kertai MD. Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study. Journal Canadien D'anesthésie 2017, 65: 46-59. PMID: 29098634, DOI: 10.1007/s12630-017-0991-0.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPostoperative acute kidney injuryCoronary artery bypassPostoperative anemiaDay of surgerySerum hemoglobin concentrationPreoperative anemiaHemoglobin concentrationArtery bypassCABG surgeryKidney injuryGlobal Outcomes (KDIGO) Clinical Practice GuidelineIncidence of AKIMultivariable Cox proportional hazards analysisSingle large academic medical centerCox proportional hazards analysisPostoperative hemoglobin concentrationPostoperative hemoglobin levelsLong-term mortalityTenth postoperative dayProportional hazards analysisRetrospective observational studyLarge academic medical centerClinical practice guidelinesPotential risk factorsDo we need another short-acting beta-blocker? A definite maybe…
Oprea AD. Do we need another short-acting beta-blocker? A definite maybe…. Journal Of Clinical Anesthesia 2017, 39: 96-97. PMID: 28494918, DOI: 10.1016/j.jclinane.2017.03.013.Peer-Reviewed Original Research
2016
Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery
Oprea AD, Lombard FW, Liu WW, White WD, Karhausen JA, Li YJ, Miller TE, Aronson S, Gan TJ, Fontes ML, Kertai MD. Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery. Anesthesia & Analgesia 2016, 123: 1480-1489. PMID: 27607474, DOI: 10.1213/ane.0000000000001557.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute Kidney InjuryAdultAgedAged, 80 and overArterial PressureChi-Square DistributionFemaleHumansHypertensionIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisNorth CarolinaOdds RatioRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexSurgical Procedures, OperativeTime FactorsTreatment OutcomeConceptsPostoperative acute kidney injuryAcute kidney injuryBaseline pulse pressureNoncardiac surgeryPulse pressureKidney injuryIncidence of AKIAdvanced stageBaseline arterial blood pressureMultivariable logistic regression analysisDuke University Medical CenterPreoperative pulse pressurePerioperative risk factorsArterial blood pressureImportant independent predictorLogistic regression analysisUniversity Medical CenterRisk-adjusted modelsCardiovascular outcomesAdult patientsBlood pressureCardiac surgeryIndependent predictorsRisk factorsMedical CenterTrans-oral Vestibular Endocrine Surgery
Udelsman R, Anuwong A, Oprea AD, Rhodes A, Prasad M, Sansone M, Brooks C, Donovan PI, Jannitto C, Carling T. Trans-oral Vestibular Endocrine Surgery. Annals Of Surgery 2016, 264: e13-e16. PMID: 27649533, DOI: 10.1097/sla.0000000000002001.Peer-Reviewed Original Research