2024
Estimates of 30-day postoperative pulmonary complications after gastrointestinal endoscopic procedures: A retrospective cohort analysis of a health system population
Carr Z, Li J, Agarkov D, Gazura M, Karamchandani K. Estimates of 30-day postoperative pulmonary complications after gastrointestinal endoscopic procedures: A retrospective cohort analysis of a health system population. PLOS ONE 2024, 19: e0299137. PMID: 38394250, PMCID: PMC10889900, DOI: 10.1371/journal.pone.0299137.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesHumansPneumoniaPneumonia, AspirationPostoperative ComplicationsRespiration DisordersRespiratory InsufficiencyRetrospective StudiesRisk FactorsConceptsPostoperative pulmonary complicationsGastrointestinal endoscopic proceduresCongestive heart failurePropensity score matchingEndoscopic proceduresPulmonary complicationsSecondary outcomesPropensity score matching adjustmentRetrospective cohort studyRetrospective cohort analysisPulmonary circulatory disordersMultivariate logistic regressionAlcohol abuse disordersUpper endoscopic proceduresHealth system populationPulmonary emboliUpper endoscopyRespiratory failureLower endoscopyElectrolyte disordersHeart failureCohort studyConscious sedationPrimary outcomeCohort analysis
2023
Predictors of Failure to Rescue After Postoperative Respiratory Failure: A Retrospective Cohort Analysis of 13,047 Patients Using the ACS-NSQIP Dataset
Karamchandani K, Khorsand S, Ebeling C, Yan L, Nakonezny P, Carr Z. Predictors of Failure to Rescue After Postoperative Respiratory Failure: A Retrospective Cohort Analysis of 13,047 Patients Using the ACS-NSQIP Dataset. Journal Of Surgical Research 2023, 293: 482-489. PMID: 37827025, DOI: 10.1016/j.jss.2023.09.030.Peer-Reviewed Original ResearchMeSH KeywordsAdultBayes TheoremCohort StudiesHumansPostoperative ComplicationsRespiratory InsufficiencyRetrospective StudiesRisk AssessmentRisk FactorsConceptsPostoperative respiratory failurePredictors of failureDay of surgeryRespiratory failureNoncardiac surgeryNational Surgical Quality Improvement Project databaseSurgeons National Surgical Quality Improvement Project databaseMultiple logistic regression modelACS-NSQIP datasetsPreoperative prealbumin levelRetrospective cohort studyAnesthesiologists physical statusRetrospective cohort analysisLogistic regression modelsPreoperative ascitesPreoperative creatininePostoperative complicationsPrealbumin levelsCohort studyStudy cohortDisseminated cancerCohort analysisAmerican CollegePatientsPhysical status
2020
Perioperative risk factors in patients with idiopathic pulmonary fibrosis: a historical cohort study
McDowell BJ, Karamchandani K, Lehman EB, Conboy MJ, Carr ZJ. Perioperative risk factors in patients with idiopathic pulmonary fibrosis: a historical cohort study. Journal Canadien D'anesthésie 2020, 68: 81-91. PMID: 33029686, DOI: 10.1007/s12630-020-01828-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesDisease ProgressionHumansIdiopathic Pulmonary FibrosisPrognosisRetrospective StudiesRisk FactorsConceptsAcute respiratory worseningIdiopathic pulmonary fibrosisOne-year mortalityHistorical cohort studyRisk factorsIPF patientsCohort studyPulmonary fibrosisSurgical timeSingle-center historical cohort studyHome oxygen requirementHome oxygen usePostoperative acute exacerbationAdverse postoperative outcomesPerioperative risk factorsIndependent risk factorDay of surgeryPerioperative risk stratificationMultivariable regression analysisActive pneumoniaAcute exacerbationAE-IPFPostoperative pneumoniaRespiratory worseningPerioperative factors
2019
CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial Fibrillation
Karamchandani K, Schoaps RS, Abendroth T, Carr ZJ, King TS, Bonavia A. CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial Fibrillation. Journal Of Cardiothoracic And Vascular Anesthesia 2019, 34: 1165-1171. PMID: 31899140, DOI: 10.1053/j.jvca.2019.11.044.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCritical IllnessHospital MortalityHumansRetrospective StudiesRisk AssessmentRisk FactorsStrokeConceptsNew-onset atrial fibrillationIntensive care unitTertiary care academic institutionHospital mortalityVASc scoreAtrial fibrillationIll patientsAdult patientsVascular diseasePrognostic markerTertiary care academic medical centerAssociation of CHAConcomitant vascular diseaseHospital mortality rateIn-Hospital MortalitySingle-center studyReliable prognostic markersAcademic medical centerElectronic medical recordsCHA2DS2-VAScHospital deathCare unitMedical recordsRetrospective analysisMedical CenterStroke prophylaxis in critically-ill patients with new-onset atrial fibrillation
Schoaps RS, Quintili A, Bonavia A, Carr ZJ, Lehman EB, Abendroth T, Karamchandani K. Stroke prophylaxis in critically-ill patients with new-onset atrial fibrillation. Journal Of Thrombosis And Thrombolysis 2019, 48: 394-399. PMID: 30963394, DOI: 10.1007/s11239-019-01854-5.Peer-Reviewed Original ResearchConceptsNew-onset atrial fibrillationCHA2DS2-VASc scoreOral anticoagulant therapyOral anticoagulantsIll patientsStroke prophylaxisAnticoagulant therapyHospital dischargeAtrial fibrillationEffective stroke prophylaxisOnset atrial fibrillationStroke/TIACongestive heart failureLong-term incidenceElectronic medical recordsEligible patientsICU survivorsAdult patientsHeart failureThromboembolic diseaseMedical recordsHigh incidencePatientsAnticoagulantsStudy period
2018
Gender differences in the use of atypical antipsychotic medications for ICU delirium
Karamchandani K, Schoaps RS, Printz J, Kowaleski JM, Carr ZJ. Gender differences in the use of atypical antipsychotic medications for ICU delirium. Critical Care 2018, 22: 220. PMID: 30236134, PMCID: PMC6148964, DOI: 10.1186/s13054-018-2143-5.Peer-Reviewed Original ResearchIncreased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis
Carr ZJ, Van De Louw A, Fehr G, Li JD, Kunselman A, Ruiz-Velasco V. Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis. BMC Research Notes 2018, 11: 41. PMID: 29338778, PMCID: PMC5771199, DOI: 10.1186/s13104-018-3165-4.Peer-Reviewed Original ResearchConceptsRNA expressionIntensive care unit admissionBlood white cell countCare unit admissionOdds of mortalityDiagnosis of sepsisBody mass indexIntensive care unitWhite cell countGPR43 expressionUnit admissionOne-unit increaseCare unitMass indexSignificant morbidityQuantitative real-time PCRGPR43 receptorInflammatory responseImmunomodulatory pathwaysReceptor 43Receptor expressionReal-time PCRSepsisCell countPatients