2005
Haemodynamic changes induced by hyperbaric bupivacaine during lateral decubitus or supine spinal anaesthesia
Kelly J, McCoy D, Rosenbaum S, Brull S. Haemodynamic changes induced by hyperbaric bupivacaine during lateral decubitus or supine spinal anaesthesia. European Journal Of Anaesthesiology 2005, 22: 717-722. PMID: 16163920, DOI: 10.1017/s0265021505001183.Peer-Reviewed Original ResearchConceptsSystolic blood pressureSpinal anesthesiaBlood pressureMaximum systolic blood pressureMean arterial pressure decreaseSystolic blood pressure decreaseArterial pressure decreaseHyperbaric bupivacaine 0.5Blood pressure decreaseL3-4 interspaceLoss of sensationOnset of hypotensionBlood pressure maintenanceLateral decubitus positionBupivacaine 0.5Hyperbaric bupivacaineIntravenous crystalloidLAT patientsPinprick sensationSmaller total dosesSympathetic denervationIntrathecal injectionArterial pressureHaemodynamic changesHaemodynamic variables
2001
Activities of daily living and cardiovascular complications following elective, noncardiac surgery.
Wiklund R, Stein H, Rosenbaum S. Activities of daily living and cardiovascular complications following elective, noncardiac surgery. The Yale Journal Of Biology And Medicine 2001, 74: 75-87. PMID: 11393264, PMCID: PMC2588693.Peer-Reviewed Original ResearchConceptsCardiac complicationsNoncardiac surgeryPhysical statusCardiac outcomesVascular surgeryDaily livingReceiver operator characteristic curve analysisOperator characteristic curve analysisPercent of complicationsPreoperative cardiac evaluationAdverse cardiac eventsAdverse cardiac outcomesAnesthesiologists physical statusPeripheral vascular occlusionReceiver operator characteristic curveLogistic regression analysisCharacteristic curve analysisOperator characteristic curveMultinomial logistic regression analysisAcute renalfailureCardiovascular complicationsRespiratory failureSevere hypertensionCardiac evaluationCardiac events
1999
The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery.
Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. Anesthesia & Analgesia 1999, 88: 477-82. PMID: 10071990, DOI: 10.1097/00000539-199903000-00002.Peer-Reviewed Original ResearchConceptsHeart rate controlMean heart ratePostoperative cardiac eventsHigh-risk patientsST-segment depressionIschemic thresholdPostoperative ischemiaMyocardial ischemiaVascular surgeryHeart rateCardiac eventsEsmolol patientsPlacebo patientsPreoperative ischemiaCardiac complicationsHigh riskHigh-risk vascular surgery patientsBeta-adrenergic blocker therapyMajor postoperative cardiac eventsStrict heart rate controlElective vascular surgeryIncidence of ischemiaPostoperative heart ratePostoperative myocardial ischemiaPreoperative myocardial ischemiaThe Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery
Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery. Anesthesia & Analgesia 1999, 88: 477-482.. DOI: 10.1213/00000539-199903000-00002.Peer-Reviewed Original ResearchConceptsHeart rate controlMean heart ratePostoperative cardiac eventsHigh-risk patientsST-segment depressionIschemic thresholdPostoperative ischemiaMyocardial ischemiaVascular surgeryHeart rateCardiac eventsEsmolol patientsPlacebo patientsPreoperative ischemiaCardiac complicationsHigh riskHigh-risk vascular surgery patientsBeta-adrenergic blocker therapyMajor postoperative cardiac eventsStrict heart rate controlElective vascular surgeryIncidence of ischemiaPostoperative heart ratePostoperative myocardial ischemiaPreoperative myocardial ischemia
1998
The Sedative and Analgesic Sparing Effect of Music
Koch M, Kain Z, Ayoub C, Rosenbaum S. The Sedative and Analgesic Sparing Effect of Music. Anesthesiology 1998, 89: 300-306. PMID: 9710387, DOI: 10.1097/00000542-199808000-00005.Peer-Reviewed Original ResearchConceptsDuration of surgeryAnalgesic requirementsIntraoperative musicPatient-controlled intravenous opioid analgesiaAnalgesic sparing effectIntravenous opioid analgesiaIntravenous propofol sedationPostanesthesia care unitEffects of musicMusic groupDuration of stayPhase 2Phase 1Operating room noiseAlfentanil requirementsOpioid analgesiaAdverse eventsLess propofolSpinal anesthesiaAwake patientsCare unitAdverse outcomesPropofol sedationSparing effectUreteral calculi
1995
Preoperative Dipyridamole Thallium Imaging and Ambulatory Electrocardiographic Monitoring as a Predictor of Perioperative Cardiac Events and Long-term Outcome
Fleisher L, Rosenbaum S, Nelson A, Jain D, Wackers F, Zaret B. Preoperative Dipyridamole Thallium Imaging and Ambulatory Electrocardiographic Monitoring as a Predictor of Perioperative Cardiac Events and Long-term Outcome. Anesthesiology 1995, 83: 906-917.. PMID: 7486176, DOI: 10.1097/00000542-199511000-00003.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overDipyridamoleElectrocardiography, AmbulatoryFemaleHeart DiseasesHumansIntraoperative ComplicationsMaleMiddle AgedPostoperative ComplicationsPredictive Value of TestsPreoperative CarePrognosisProspective StudiesRadionuclide AngiographySensitivity and SpecificitySurvival AnalysisThallium RadioisotopesVasodilator AgentsConceptsPerioperative cardiac eventsPredictive valueDipyridamole thalliumCardiac eventsPreoperative dipyridamole thallium imagingLong-term cardiac survivalGreatest likelihood ratioNoncardiac surgery patientsPerioperative cardiac morbidityDipyridamole-thallium imagingLong-term mortalityLong-term prognosisAmbulatory electrocardiographic monitoringShort-term outcomesLong-term outcomesLikelihood ratioPositive predictive valueLog-rank statisticsNuclear cardiology laboratoryCardiac morbidityNoncardiac surgerySurgery patientsThallium imagingCardiac survivalElectrocardiographic monitoringThrombocytopenia in pregnant women who use cocaine
Kain Z, Mayes L, Pakes J, Rosenbaum S, Schottenfeld R. Thrombocytopenia in pregnant women who use cocaine. American Journal Of Obstetrics And Gynecology 1995, 173: 885-890. PMID: 7573263, DOI: 10.1016/0002-9378(95)90360-7.Peer-Reviewed Original ResearchConceptsLow platelet countDrug-free groupPlatelet countCocaine groupHuman immunodeficiency virus statusCocaine-abusing parturientsRate of thrombocytopeniaIndependent risk factorAssociation of thrombocytopeniaCocaine-using groupIllicit drug useParturient populationSeropositive womenCohort studyPregnant womenDrug groupsPrenatal centersMedical recordsRisk factorsVirus statusMedical conditionsThrombocytopeniaIllicit drug usageNineteen subjectsOpiate groupPostoperative myocardial ischemia: Etiology of cardiac morbidity or manifestation of underlying disease?
Fleisher L, Nelson A, Rosenbaum S. Postoperative myocardial ischemia: Etiology of cardiac morbidity or manifestation of underlying disease? Journal Of Clinical Anesthesia 1995, 7: 97-102. PMID: 7598933, DOI: 10.1016/0952-8180(94)00030-8.Peer-Reviewed Original ResearchConceptsST-segment changesNoncardiac surgery patientsCardiac eventsSegment changesCardiac morbiditySurgery patientsMyocardial ischemiaThird postoperative dayTertiary care hospitalGroup of patientsTransient ST segment changesIntensive care unitCK-MB isoenzymeAmbulatory electrocardiographic recordersGeneral inpatientsCare hospitalCohort studyPostoperative dayCare unitSurgical periodCardiac ischemiaPatientsMorbidityAmbulatory ECGElectrocardiographic recorder
1993
Relationship between postoperative anemia and cardiac morbidity in high-risk vascular patients in the intensive care unit
NELSON A, FLEISHER L, ROSENBAUM S. Relationship between postoperative anemia and cardiac morbidity in high-risk vascular patients in the intensive care unit. Critical Care Medicine 1993, 21: 860-866. PMID: 8504653, DOI: 10.1097/00003246-199306000-00013.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnemiaBlood TransfusionCase-Control StudiesConnecticutElectrocardiography, AmbulatoryFemaleHematocritHumansIncidenceIntensive Care UnitsMaleMyocardial InfarctionMyocardial IschemiaPeripheral Vascular DiseasesPostoperative ComplicationsRecovery RoomRisk FactorsROC CurveSensitivity and SpecificityConceptsMorbid cardiac eventsPostoperative myocardial ischemiaCardiac eventsIntensive care unitMyocardial ischemiaPostoperative anemiaCare unitCardiac morbidityHeart rateExact testHigh-risk vascular patientsSurgical intensive care unitIschemic pulmonary edemaHigh-risk patientsPostanesthesia care unitST-segment elevationBaseline heart rateCase-control studyFisher's exact testArterial bypass proceduresAmbulatory electrocardiographic recordersNonanemic patientsCardiac outcomesPostoperative periodUnstable anginaApproximate Entropy of Heart Rate as a Correlate of Postoperative Ventricular Dysfunction
Fleisher L, Pincus S, Rosenbaum S. Approximate Entropy of Heart Rate as a Correlate of Postoperative Ventricular Dysfunction. Anesthesiology 1993, 78: 683-692. PMID: 8466069, DOI: 10.1097/00000542-199304000-00011.Peer-Reviewed Original ResearchGender independence of ambulatory electrocardiographic monitoring in predicting perioperative cardiac risk
Fleisher L, Rosenbaum S, Nelson A, Rosenfeld L. Gender independence of ambulatory electrocardiographic monitoring in predicting perioperative cardiac risk. The American Journal Of Cardiology 1993, 71: 241-242. PMID: 8421990, DOI: 10.1016/0002-9149(93)90745-x.Peer-Reviewed Original ResearchConceptsAmbulatory electrocardiographic monitoringCardiac riskElectrocardiographic monitoringMyocardial ischemiaMorbid cardiac eventsPerioperative cardiac morbidityPerioperative cardiac riskPostoperative myocardial ischemiaHigh-risk patientsCoronary artery diseaseCardiac morbidityNoncardiac surgerySilent ischemiaArtery diseaseCardiac eventsECG changesAmbulatory monitoringMale populationIschemiaWomenStrongest predictorRiskMorbidityPatientsSurgery
1992
ST Segment Depression during Labor and Delivery
Mathew J, Fleisher L, Rinehouse J, Sevarino F, Sinatra R, Nelson A, Prokop E, Rosenbaum S. ST Segment Depression during Labor and Delivery. Anesthesiology 1992, 77: 635-641. PMID: 1416160, DOI: 10.1097/00000542-199210000-00004.Peer-Reviewed Original ResearchConceptsST-segment depressionEjection fraction areaSegment depressionCesarean deliveryVenous air embolismST depressionAir embolismRegional wall motion abnormalitiesContinuous ambulatory ECGST-segment elevationWall motion abnormalitiesPrecordial Doppler monitoringCesarean sectionMyocardial impairmentVaginal deliverySegment elevationGeneral anesthesiaECG changesMotion abnormalitiesMyocardial ischemiaDoppler monitoringRegional anesthesiaST changesEchocardiographic imagingFraction areaFailure of negative dipyridamole thallium scans to predict perioperative myocardial ischaemia and infarction
Fleisher L, Nelson A, Rosenbaum S. Failure of negative dipyridamole thallium scans to predict perioperative myocardial ischaemia and infarction. Journal Canadien D'anesthésie 1992, 39: 179-183. PMID: 1544202, DOI: 10.1007/bf03008653.Peer-Reviewed Original ResearchConceptsDipyridamole-thallium scanPostoperative dayThallium scansMyocardial infarctionPreoperative dipyridamole thallium imagingUnderlying coronary artery diseaseDipyridamole-thallium imagingPostoperative myocardial infarctionThird postoperative dayCoronary artery diseasePerioperative myocardial ischaemiaFalse-negative scansHigh-risk populationAmbulatory electrocardiographic recordersPostoperative ischaemiaArtery diseaseThallium imagingThird patientMyocardial ischaemiaNegative scansIschaemiaElectrocardiographic recorderInfarctionPatientsPeriod of monitoring
1991
The predictive value of preoperative silent ischemia for postoperative ischemic cardiac events in vascular and nonvascular surgery patients
Fleisher L, Rosenbaum S, Nelson A, Barash P. The predictive value of preoperative silent ischemia for postoperative ischemic cardiac events in vascular and nonvascular surgery patients. American Heart Journal 1991, 122: 980-986. PMID: 1927885, DOI: 10.1016/0002-8703(91)90461-p.Peer-Reviewed Original ResearchConceptsPostoperative cardiac eventsSilent ischemiaCardiac eventsSurgery patientsPredictive valueMorbid cardiac eventsVascular surgical patientsVascular surgery patientsIschemic cardiac eventsSilent myocardial ischemiaSimilar predictive valueNonvascular surgerySurgical groupSurgical patientsVascular patientsExcellent outcomesCoronary circulationFunctional statusMyocardial ischemiaVascular surgeryCardiac diseaseIschemiaPatientsSurgeryOutcomes