Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors
Tao J, Bukanova EN, Akhtar S. Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors. Journal Of Intensive Care 2018, 6: 34. PMID: 29942519, PMCID: PMC6001072, DOI: 10.1186/s40560-018-0303-y.Peer-Reviewed Original ResearchSequential compression devicesFactor Xa inhibitorsThrombotic eventsProthrombin complex concentrateXa inhibitorsMajor bleedingEmergent reversalComplex concentrateInvasive proceduresIU/Single-center retrospective reviewChronic oral anticoagulationEmergent decompressive craniotomyRate of thromboembolismResultsForty-three patientsUpper extremity DVTMulticenter prospective trialDeep vein thrombosisTreatment of choiceCerebral vascular accidentMinor invasive proceduresTraumatic intracranial hemorrhageRisk of thrombosisEmergent invasive proceduresDVT prophylaxis