- Factor VIIIFactor replacementHemophilia AFactor XIFactor IXExogenous factor VIIIRecessive inheritance patternCoagulation workupElevated aPTTPlatelet countProthrombin concentrateSevere haemophiliaPlatelet functionCongenital deficiencyFactor VIIPatientsHemophiliaSpecific mutationsDisordersFIX concentrationInheritance patternLow levelsDeficiencyAntifibrinolyticsNSAIDs