2010
Coronary stents: factors contributing to perioperative major adverse cardiovascular events
Barash P, Akhtar S. Coronary stents: factors contributing to perioperative major adverse cardiovascular events. British Journal Of Anaesthesia 2010, 105: i3-i15. PMID: 21148653, DOI: 10.1093/bja/aeq318.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAdverse cardiovascular eventsCardiovascular eventsStent thrombosisRisk factorsPerioperative major adverse cardiovascular eventsContinuation of aspirinDual antiplatelet therapyNon-cardiac surgeryRisk of bleedingPercutaneous coronary interventionCoronary blood flowMajor risk factorDominant risk factorBare metal stentsDrug-eluting stentsNeuraxial anesthetic techniquesHigh mortality rateClopidogrel therapyAntiplatelet therapyCoronary interventionEpidural haematomaElective surgeryAnesthetic techniqueMyocardial ischaemia
2004
Assessment and management of patients with ischemic heart disease
Akhtar S, Silverman DG. Assessment and management of patients with ischemic heart disease. Critical Care Medicine 2004, 32: s126-s136. PMID: 15064671, DOI: 10.1097/01.ccm.0000121576.73871.2d.Peer-Reviewed Original ResearchConceptsIschemic heart diseasePerioperative cardiac morbidityHeart diseaseCardiac morbidityNoncardiac surgeryPerioperative cardiovascular outcomesPreoperative evaluation processPerioperative myocardial infarctionManagement of patientsAlpha-2 agonistsCardiac-specific biomarkersAmerican Heart AssociationIntraoperative anesthetic techniqueReview of literatureCardiovascular outcomesPerioperative managementPharmacologic therapyPostoperative managementAnesthetic techniqueHeart AssociationHemodynamic controlJoint guidelinesMyocardial infarctionAmerican CollegeHemodynamic stress
1999
INTRAOPERATIVE USE OF ANTICOAGULANTS AND ANTITHROMBOTICS Heparin and Beyond
Akhtar S, Brull S. INTRAOPERATIVE USE OF ANTICOAGULANTS AND ANTITHROMBOTICS Heparin and Beyond. Anesthesiology Clinics 1999, 17: 831-860. DOI: 10.1016/s0889-8537(05)70136-x.ChaptersDeep vein thrombosisThrombus formationUnfractionated heparinSurgical interventionHemostatic systemIntraoperative useFatal pulmonary embolismVascular reconstructive proceduresCertain surgical interventionsArterial thrombus formationCardiopulmonary bypass proceduresLess side effectsNew anticoagulant agentsCertain surgical proceduresWide clinical useSubepithelial surfaceAntithrombotic therapyPulmonary embolismVein thrombosisAnesthetic implicationsIntraoperative anticoagulationAnesthetic techniqueBypass proceduresPerioperative monitoringClinical management