Elimination of Gaseous Microemboli From Cardiopulmonary Bypass Using Hypobaric Oxygenation
Gipson KE, Rosinski DJ, Schonberger RB, Kubera C, Mathew ES, Nichols F, Dyckman W, Courtin F, Sherburne B, Bordey AF, Gross JB. Elimination of Gaseous Microemboli From Cardiopulmonary Bypass Using Hypobaric Oxygenation. The Annals Of Thoracic Surgery 2013, 97: 879-886. PMID: 24206970, PMCID: PMC4294693, DOI: 10.1016/j.athoracsur.2013.08.074.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassSweep gasGaseous microemboliEnd-organ damageApparent adverse eventsEnd-organ tissuesDose-dependent reductionCurrent practice standardsVariety of patientsMicrovascular injuryGas pressureMicroporous membrane oxygenatorAdverse eventsCardiac surgeryCPB circuitAir embolismExtracorporeal circulationArterial circulationArterial bloodEnd organsGME volumeArterial filterProgressive reabsorptionAortic cannulaDissolved gases