In vivo responses of cutaneous C-mechanosensitive neurons in mouse to punctate chemical stimuli that elicit itch and nociceptive sensations in humans
Ma C, Nie H, Gu Q, Sikand P, LaMotte RH. In vivo responses of cutaneous C-mechanosensitive neurons in mouse to punctate chemical stimuli that elicit itch and nociceptive sensations in humans. Journal Of Neurophysiology 2011, 107: 357-363. PMID: 21994268, PMCID: PMC3349700, DOI: 10.1152/jn.00801.2011.Peer-Reviewed Original ResearchConceptsNociceptive sensationsCowhage spiculesC-nociceptorsNociceptive neuronsReceptive fieldsCutaneous receptive fieldsNoxious mechanical stimuliC-fibre rangePeripheral neural mechanismsExtracellular electrophysiological recordingsAxonal conduction velocityMean discharge rateChemical itchElicit itchChemical stimuliMechanosensitive nociceptorsConduction velocityMechanosensitive neuronsHeat stimuliItchCell bodiesElectrophysiological recordingsVivo responseCapsaicinHistamine