2006
Effects of a Chronic Compression of the Dorsal Root Ganglion on Voltage-Gated Na+ and K+ Currents in Cutaneous Afferent Neurons
Tan Z, Donnelly D, LaMotte R. Effects of a Chronic Compression of the Dorsal Root Ganglion on Voltage-Gated Na+ and K+ Currents in Cutaneous Afferent Neurons. Journal Of Neurophysiology 2006, 95: 1115-1123. PMID: 16424456, DOI: 10.1152/jn.00830.2005.Peer-Reviewed Original ResearchConceptsDorsal root gangliaCCD neuronsRoot gangliaChronic compressionTTX-sensitiveL5 dorsal root gangliaWhole-cell patch-clamp recordingsCell patch-clamp recordingsCutaneous afferent neuronsEnhanced neuronal excitabilityTTX-resistant currentSteady-state activation curvePatch-clamp recordingsCutaneous hyperalgesiaCutaneous neuronsDRG somataAfferent neuronsControl neuronsControl ratsNeuronal somataNeuronal excitabilityAdult ratsSpontaneous activityIntervertebral foraminaLower rheobase
1996
Multiple capsaicin-induced currents in isolated rat sensory neurons
Petersen M, LaMotte R, Klusch A, Kniffki K. Multiple capsaicin-induced currents in isolated rat sensory neurons. Neuroscience 1996, 75: 495-505. PMID: 8931013, DOI: 10.1016/0306-4522(96)00259-x.Peer-Reviewed Original ResearchConceptsDistinct current componentsConcentrations of capsaicinDorsal root ganglion cellsRat sensory neuronsCapsaicin-induced currentsPresent patch-clamp studyExtracellular solutionPatch-clamp studiesNM capsaicinSecond current componentCapsaicin actionGanglion cellsSensory neuronsCapsaicinSecondary responseFunctional assaysProlonged application