1991
Psychophysical Studies of the Itch Sensation and Itchy Skin (“Alloknesis”) Produced by Intracutaneous Injection of Histamine
Simone D, Alreja M, Lamotte R. Psychophysical Studies of the Itch Sensation and Itchy Skin (“Alloknesis”) Produced by Intracutaneous Injection of Histamine. Somatosensory & Motor Research 1991, 8: 271-279. PMID: 1767623, DOI: 10.3109/08990229109144750.Peer-Reviewed Original ResearchConceptsDuration of itchSubcutaneous injectionIntracutaneous injectionItchy skinArea of alloknesisSensation of itchMicrograms of histamineSkin temperatureItch sensationLocal anesthesiaAlloknesisMean latencyInjection siteMean maximum areaItchHuman volunteersHistamineVolar forearmDose-response functionInjectionNeural mechanismsSkinDoseDurationMicrograms
1987
The Magnitude and Duration of Itch Produced by Intracutaneous Injections of Histamine
Simone D, Ngeow J, Whitehouse J, Becerra-Cabal L, Putterman G, Lamotte R. The Magnitude and Duration of Itch Produced by Intracutaneous Injections of Histamine. Somatosensory & Motor Research 1987, 5: 81-92. PMID: 3423533, DOI: 10.3109/07367228709144620.Peer-Reviewed Original ResearchConceptsDuration of itchArea of flareIntracutaneous injectionDose-dependent fashionHistamine doseMicrograms of histaminePeripheral neural mechanismsDose-dependent mannerIntracutaneous histamineItch magnitudeItch sensationLow doseItchHistamineVolar forearmDoseNeurophysiological studiesLonger durationMicrogramsMultiple injectionsInjectionNeural mechanismsDurationWeeksSubjects