2006
MCP-1 Enhances Excitability of Nociceptive Neurons in Chronically Compressed Dorsal Root Ganglia
Sun J, Yang B, Donnelly D, Ma C, LaMotte R. MCP-1 Enhances Excitability of Nociceptive Neurons in Chronically Compressed Dorsal Root Ganglia. Journal Of Neurophysiology 2006, 96: 2189-2199. PMID: 16775210, DOI: 10.1152/jn.00222.2006.Peer-Reviewed Original ResearchConceptsMonocyte chemoattractant protein-1Dorsal root gangliaNociceptive neuronsRoot gangliaCompressed dorsal root ganglionIntact dorsal root gangliaSmall DRG neuronsProportion of neuronsChemoattractant protein-1Action potential widthNonselective cation conductanceMagnitude of depolarizationCCD neuronsChronic compressionDRG neuronsExcitatory effectsReceptor CCR2Nociceptive propertiesIntact gangliaNeuronal expressionInward currentsNeuronsCurrent clampGangliaReversal potential
1998
Patch clamp recording from the intact dorsal root ganglion
Zhang J, Donnelly D, LaMotte R. Patch clamp recording from the intact dorsal root ganglion. Journal Of Neuroscience Methods 1998, 79: 97-103. PMID: 9531465, DOI: 10.1016/s0165-0270(97)00164-7.Peer-Reviewed Original ResearchConceptsPatch-clamp recordingsConduction velocityAction potentialsSciatic nerveC cellsIntact dorsal root gangliaDorsal root ganglion cellsDorsal root gangliaAxonal conduction velocityGanglion sheathL5 DRGDRG cellsRoot gangliaGanglion cellsAP thresholdBeta cellsClamp recordingsSodium currentAdeltaCurrent clampConnective tissueVoltage clampNerveGangliaTTX