1995
Functional changes in dorsal root ganglion cells after chronic nerve constriction in the rat
Xie Y, Zhang J, Petersen M, LaMotte R. Functional changes in dorsal root ganglion cells after chronic nerve constriction in the rat. Journal Of Neurophysiology 1995, 73: 1811-1820. PMID: 7623082, DOI: 10.1152/jn.1995.73.5.1811.Peer-Reviewed Original ResearchConceptsDorsal root gangliaChronic nerve constrictionMost C-fibersC-fibersNerve constrictionSpontaneous activityInjury siteDRG somataDorsal rootsDorsal root ganglion cellsNerve-injured ratsIpsilateral sciatic nerveL5 dorsal rootAlpha 2 receptorsEffects of norepinephrineDorsal root fibersThermal stimuliUninjured neuronsUninjured ratsNerve injurySympathetic trunkUninjured nerveSympathetic stimulationCutaneous painExcitatory responses
1988
Chapter 39 Psychophysical and neurophysiological studies of chemically induced cutaneous pain and itch The case of the missing nociceptor
LaMotte R. Chapter 39 Psychophysical and neurophysiological studies of chemically induced cutaneous pain and itch The case of the missing nociceptor. Progress In Brain Research 1988, 74: 331-335. PMID: 3187041, DOI: 10.1016/s0079-6123(08)63033-2.Peer-Reviewed Original ResearchConceptsCutaneous painInjection siteNeurophysiological studiesPeripheral nerve fibersSensation of painCapsaicin painInjection painMechanical hyperesthesiaHeat hyperalgesiaHeat nociceptorsIntradermal injectionCutaneous receptorsNerve fibersHistamine dihydrochloridePainNociceptorsCapsaicinGreater painItchAllodyniaHyperesthesiaFurther investigationCandidate mechanismInjectionSensation
1984
Time-intensity profiles of cutaneous pain in normal and hyperalgesic skin: a comparison with C-fiber nociceptor activities in monkey and human
LaMotte R, Torebjörk H, Robinson C, Thalhammer J. Time-intensity profiles of cutaneous pain in normal and hyperalgesic skin: a comparison with C-fiber nociceptor activities in monkey and human. Journal Of Neurophysiology 1984, 51: 1434-1450. PMID: 6737035, DOI: 10.1152/jn.1984.51.6.1434.Peer-Reviewed Original ResearchConceptsNociceptive afferent fibersDevelopment of hyperalgesiaConditioning stimulusPain ratingsHeat stimulationAfferent fibersHairy skinHeat-evoked dischargesCervical spinal cordMagnitude of painMild heat injurySimilar response magnitudesMean frequencyPoststimulus time histogramsNociceptor activityCutaneous painResponse latencyHyperalgesic skinSpinal cordAwake humansC-fibersAnesthetized monkeysConduction velocityPainHeat stimuliPeripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: simultaneous recordings in humans of sensory judgments of pain and evoked responses in nociceptors with C-fibers
Torebjörk H, LaMotte R, Robinson C. Peripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: simultaneous recordings in humans of sensory judgments of pain and evoked responses in nociceptors with C-fibers. Journal Of Neurophysiology 1984, 51: 325-339. PMID: 6707724, DOI: 10.1152/jn.1984.51.2.325.Peer-Reviewed Original ResearchConceptsConditioning stimulusIntensity-response functionsNormal skinMost subjectsC-mechanoheat nociceptorsPeripheral neural correlateHeat pain sensationMild heat injuryMagnitude ratingsReceptive fieldsHeat injurySupra-threshold stimuliShort-duration stimuliPain thresholdCutaneous painHeat painPain sensationC-fibersPainNociceptorsHairy skinUninjured skinHeat stimulationMagnitude of responseNeuronal correlates
1983
Peripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: a comparison of neural events in monkey with sensory judgments in human
LaMotte R, Thalhammer J, Robinson C. Peripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: a comparison of neural events in monkey with sensory judgments in human. Journal Of Neurophysiology 1983, 50: 1-26. PMID: 6875640, DOI: 10.1152/jn.1983.50.1.1.Peer-Reviewed Original Research