Cystatin C as a cerebrospinal fluid biomarker for pain in humans
Mannes A, Martin B, Yang H, Keller J, Lewin S, Gaiser R, Iadarola M. Cystatin C as a cerebrospinal fluid biomarker for pain in humans. Pain 2003, 102: 251-256. PMID: 12670666, DOI: 10.1016/s0304-3959(02)00403-7.Peer-Reviewed Original ResearchConceptsCerebrospinal fluidCystatin CMcGill Short Form QuestionnaireCystatin C increaseNon-pain patientsElective caesarean sectionBeta-endorphin contentDorsal spinal cordVisual analog scaleCerebrospinal fluid biomarkersTotal CSF proteinPrevious animal studiesShort-form questionnairePeripheral inflammationCaesarean sectionSevere painDorsal hornPain statesPersistent painPain patientsAnalog scaleObstetrical patientsFluid biomarkersControl subjectsSpinal cord