2015
Dexmedetomidine Does Not Affect Evoked Potentials During Spine Surgery
Rozet I, Metzner J, Brown M, Treggiari MM, Slimp JC, Kinney G, Sharma D, Lee LA, Vavilala MS. Dexmedetomidine Does Not Affect Evoked Potentials During Spine Surgery. Anesthesia & Analgesia 2015, 121: 492-501. PMID: 26097987, DOI: 10.1213/ane.0000000000000840.Peer-Reviewed Original ResearchMeSH KeywordsAnesthesia, IntravenousAnesthetics, IntravenousDexmedetomidineDouble-Blind MethodEvoked PotentialsEvoked Potentials, MotorEvoked Potentials, SomatosensoryEvoked Potentials, VisualFemaleHumansHypnotics and SedativesIntraoperative Neurophysiological MonitoringMaleMiddle AgedOrthopedic ProceduresPiperidinesPropofolReaction TimeRemifentanilSpineTime FactorsConceptsEffect of dexmedetomidineVisual EPsSpine surgeryEnd pointElective spine surgeryPlacebo-controlled trialPrimary end pointSecondary end pointsLatency N1Motor EPsPlacebo groupStudy drugAdult patientsNormal salineLatency P1DexmedetomidineSomatosensory EPsIRB approvalRelevant dosesEP recordingInformed consentPatientsSurgeryEvoked PotentialsAnesthesia
2009
Prolonged Propofol Anesthesia Is Not Associated with an Increase in Blood Lactate
Rozet I, Tontisirin N, Vavilala MS, Treggiari MM, Lee LA, Lam AM. Prolonged Propofol Anesthesia Is Not Associated with an Increase in Blood Lactate. Anesthesia & Analgesia 2009, 109: 1105-1110. PMID: 19641048, DOI: 10.1213/ane.0b013e3181b5a220.Peer-Reviewed Original ResearchConceptsPropofol groupVolatile anesthesiaBlood lossAnesthesia timeSpine surgeryElective spine surgeryHigh serum lactateIntraoperative hemodynamic variablesProlonged spine surgeryPropofol infusion syndromeUse of vasopressorsPropofol patientsVA casesASA gradeInfusion syndromeSerum lactateArterial lactatePropofol infusionProspective studyHemodynamic variablesVA patientsPropofol anesthesiaIntraoperative dataLactic acidosisBlood lactate