Improved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation
Dale CR, Kannas DA, Fan VS, Daniel SL, Deem S, Yanez ND, Hough CL, Dellit TH, Treggiari MM. Improved Analgesia, Sedation, and Delirium Protocol Associated with Decreased Duration of Delirium and Mechanical Ventilation. Annals Of The American Thoracic Society 2014, 11: 367-374. PMID: 24597599, PMCID: PMC4028734, DOI: 10.1513/annalsats.201306-210oc.Peer-Reviewed Original ResearchConceptsCAM-ICU assessmentsIntensive care unitMechanical ventilationMedian durationICU stayBenzodiazepine doseSedation protocolPatient assessmentBaseline cohortTrauma-surgical intensive care unitConfusion Assessment Method-ICURichmond Agitation-Sedation Scale scorePrespecified secondary endpointSedation Scale scoreDays of deliriumImproved patient outcomesMultivariable linear regressionBenzodiazepine dosingBenzodiazepine exposureDelirium protocolHospital mortalityPneumonia ratesProtocol cohortRASS assessmentsImproved analgesia