2008
Intensive insulin therapy and mortality in critically ill patients
Treggiari MM, Karir V, Yanez ND, Weiss NS, Daniel S, Deem SA. Intensive insulin therapy and mortality in critically ill patients. Critical Care 2008, 12: r29. PMID: 18312617, PMCID: PMC2374630, DOI: 10.1186/cc6807.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesCritical CareDose-Response Relationship, DrugFemaleGlycemic IndexHospital MortalityHumansHypoglycemiaHypoglycemic AgentsInsulinIntensive Care UnitsLength of StayMaleMiddle AgedMultiple Organ FailureRandomized Controlled Trials as TopicRegression AnalysisSeverity of Illness IndexTrauma CentersConceptsIntensive care unitHospital mortalityIll patientsSequential Organ Failure Assessment scoreOrgan Failure Assessment scorePost-cardiac surgery patientsLevel 1 trauma centerExcess hospital mortalityAdjusted hospital mortalityOccurrence of hypoglycemiaTight glycemic controlMain study endpointMultivariable regression analysisPeriod IIICU lengthPeriod IIICohort studyInsulin therapySurgery patientsGlycemic controlOrgan dysfunctionStudy endpointCare unitTrauma centerStudy population
2004
Transpulmonary lactate gradient after hypothermic cardiopulmonary bypass
Bendjelid K, Treggiari MM, Romand JA. Transpulmonary lactate gradient after hypothermic cardiopulmonary bypass. Intensive Care Medicine 2004, 30: 817-821. PMID: 14985958, DOI: 10.1007/s00134-004-2179-7.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypass durationAcute lung injuryPulmonary lactate releaseCardiopulmonary bypassBypass durationLactate releaseAortic cross-clamping timeEffects of CPBPost-cardiac surgery patientsCross-clamping timePulmonary artery catheterVenous blood samplesHypothermic cardiopulmonary bypassConclusionThe present studyPulmonary releaseCardiac indexArtery catheterLung injurySurgery patientsSurgical ICUMechanical ventilationCardiac outputUniversity HospitalBlood samplesPatients