Effect of increasing norepinephrine dosage on regional blood flow in a porcine model of endotoxin shock*
Treggiari MM, Romand JA, Burgener D, Suter PM, Aneman A. Effect of increasing norepinephrine dosage on regional blood flow in a porcine model of endotoxin shock*. Critical Care Medicine 2002, 30: 1334-1339. PMID: 12072691, DOI: 10.1097/00003246-200206000-00032.Peer-Reviewed Original ResearchConceptsMean arterial pressureArterial pressureCardiac outputRenal arteryEndotoxic shockPortal veinBlood flowPorcine modelPortal vein blood flowAdministration of norepinephrineEndotoxic shock modelSystemic oxygen extractionVein blood flowEnhanced cardiac outputLaser Doppler flowmetryRegional blood flowAcute endotoxic shock modelAcute interventional studyAnimal research laboratoryEndotoxemic controlsJejunal tonometryNorepinephrine dosageRenal perfusionAcute modelInterventional study