2024
Association of Early Dexmedetomidine Utilization With Clinical Outcomes After Moderate-Severe Traumatic Brain Injury: A Retrospective Cohort Study
Liu S, Kelly-Hedrick M, Komisarow J, Hatfield J, Ohnuma T, Treggiari M, Colton K, Arulraja E, Vavilala M, Laskowitz D, Mathew J, Hernandez A, James M, Raghunathan K, Krishnamoorthy V. Association of Early Dexmedetomidine Utilization With Clinical Outcomes After Moderate-Severe Traumatic Brain Injury: A Retrospective Cohort Study. Anesthesia & Analgesia 2024, 139: 366-374. PMID: 38335145, PMCID: PMC11250935, DOI: 10.1213/ane.0000000000006869.Peer-Reviewed Original ResearchLength of stayTraumatic brain injuryImprove patient outcomesModerate-severe TBIRetrospective cohort studyMechanical ventilationMechanically ventilated patientsDexmedetomidine exposureDay of admissionCohort studyHospital mortalityOdds of hospital mortalityPatient outcomesAssociated with reduced oddsCohort of critically ill adult patientsPrimary outcome of hospital mortalityReduce length of stayHospital costsAssociated with oddsOutcome of hospital mortalityCritically ill adult patientsDay of ICU admissionHospital length of stayIll adult patientsPublic health problem
2011
Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury
Chaiwat O, Vavilala MS, Philip S, Malakouti A, Neff MJ, Deem S, Treggiari MM, Wang J, Lang JD. Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. Journal Of Critical Care 2011, 26: 144-151. PMID: 20869200, DOI: 10.1016/j.jcrc.2010.08.002.Peer-Reviewed Original ResearchMeSH KeywordsAcute Lung InjuryAdolescentAdultAgedAged, 80 and overAPACHECritical IllnessFemaleGuideline AdherenceHospital MortalityHumansInjury Severity ScoreIntraoperative PeriodLength of StayMaleMiddle AgedPositive-Pressure RespirationPractice Guidelines as TopicRetrospective StudiesRisk FactorsTidal VolumeYoung AdultConceptsAcute respiratory distress syndromeAcute lung injuryALI/acute respiratory distress syndromeLTV ventilationLung injuryClinical outcomesLow tidal volume ventilation strategyALI/ARDS diagnosisLow tidal volume ventilationVolume ventilation strategyRespiratory distress syndromeTidal volume ventilationARDS diagnosisHospital mortalityIntraoperative adherenceHospital lengthSecondary outcomesSurgical patientsDistress syndromeIll patientsVolume ventilationImproved oxygenationPatient outcomesRetrospective analysisMAIN OUTCOME
2010
New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference?
Deem S, Treggiari MM. New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference? Respiratory Care 2010, 55: 1046-55. PMID: 20667152.Peer-Reviewed Original ResearchConceptsEndotracheal tubeVAP preventionVentilator-associated pneumoniaNew endotracheal tubeImportant patient outcomesInfection control methodsModified Endotracheal TubeCost-effectiveness dataProper patient positioningOral hygienePatient outcomesNosocomial infectionsInsufficient evidencePatient careStrong recommendationsImportant safety concernsPatient positioningMeticulous attentionPneumoniaSuch interventionsMicroaspirationSafety concernsMultifaceted approachPreventionFuture studies
2008
The effect of an intensive care unit staffing model on tidal volume in patients with acute lung injury
Cooke CR, Watkins TR, Kahn JM, Treggiari MM, Caldwell E, Hudson LD, Rubenfeld GD. The effect of an intensive care unit staffing model on tidal volume in patients with acute lung injury. Critical Care 2008, 12: r134. PMID: 18980682, PMCID: PMC2646342, DOI: 10.1186/cc7105.Peer-Reviewed Original ResearchConceptsClosed intensive care unitAcute lung injuryIntensive care unitLung injuryCare unitTidal volumeProspective population-based cohortLow VTOpen intensive care unitIntensivist physician staffingPopulation-based cohortProcess of careHospital mortalityVentilatory practicesImproved mortalityIntensive carePhysician staffingPatient outcomesMean VTPatientsDay threeSecondary analysisPotential patientsHigh VTKing County