2021
High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modeling
Sphabmixay P, Raredon M, Wang A, Lee H, Hammond P, Fang N, Griffith L. High resolution stereolithography fabrication of perfusable scaffolds to enable long-term meso-scale hepatic culture for disease modeling. Biofabrication 2021, 13: 045024. PMID: 34479229, DOI: 10.1088/1758-5090/ac23aa.Peer-Reviewed Original Research
2014
Bioreactor technologies to support liver function in vitro
Ebrahimkhani MR, Neiman JA, Raredon MS, Hughes DJ, Griffith LG. Bioreactor technologies to support liver function in vitro. Advanced Drug Delivery Reviews 2014, 69: 132-157. PMID: 24607703, PMCID: PMC4144187, DOI: 10.1016/j.addr.2014.02.011.Peer-Reviewed Original ResearchConceptsSmall molecule drugsNucleic acid therapyNew experimental modelPrediction of metabolismImmunologic homeostasisAcid therapyLiver functionDrug discoveryMolecule drugsLiver physiologyExperimental modelLong-term liver-specific functionDisease modelsDrug developmentMolecular therapeuticsTarget effectsTherapeuticsWide spectrumIndirect targetsPathophysiologyTherapyLiver-specific functions