2018
The role of sciatic nerve block to complement femoral nerve block in total knee arthroplasty: a meta-analysis of randomized controlled trials
Zorrilla-Vaca A, Li J. The role of sciatic nerve block to complement femoral nerve block in total knee arthroplasty: a meta-analysis of randomized controlled trials. Journal Of Anesthesia 2018, 32: 341-350. PMID: 29520522, DOI: 10.1007/s00540-018-2480-1.Peer-Reviewed Original ResearchConceptsSciatic nerve blockTotal knee arthroplastyContinuous sciatic nerve blockPatient-controlled analgesiaNerve blockPain scoresStandardized mean differenceOpioid consumptionKnee arthroplastySingle-injection sciatic nerve blockControl groupSciatic-femoral nerve blockIntravenous opioid consumptionPostoperative analgesic benefitsPostoperative opioid consumptionIncidence of nauseaFemoral nerve blockLess pain scoresRandom-effects modelSystematic literature searchEvidence-based supportAnalgesic benefitHospital stayAcute painRandomized trialsDexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks
Zorrilla-Vaca A, Li J. Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks. The Clinical Journal Of Pain 2018, 34: 276-284. PMID: 28591086, DOI: 10.1097/ajp.0000000000000519.Peer-Reviewed Original ResearchConceptsPeripheral nerve blocksDuration of analgesiaPerineural dexamethasoneOpioid consumptionPain scoresPostoperative nauseaSensory blockNerve blockMotor block durationPain modulation mechanismsPerioperative pain controlPreservative-free dexamethasoneBetter analgesic effectDose of dexamethasoneTerms of prolongationSubgroup of studiesRandom-effects modelIntravenous dexamethasonePain controlAnalgesic effectMotor blockPostoperative outcomesAdministered IntravenouslyIntraoperative eventsSystemic absorption
2016
The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty
Zorrilla-Vaca A, Grant MC, Mathur V, Li J, Wu CL. The Impact of Neuraxial Versus General Anesthesia on the Incidence of Postoperative Surgical Site Infections Following Knee or Hip Arthroplasty. Regional Anesthesia & Pain Medicine 2016, 41: 555-563. PMID: 27380106, DOI: 10.1097/aap.0000000000000437.Peer-Reviewed Original ResearchConceptsPostoperative surgical site infectionSurgical site infectionKnee arthroplastyHip arthroplastySite infectionNeuraxial anesthesiaGeneral anesthesiaSubgroup analysisOdds ratioDevelopment of SSIPooled unadjusted odds ratioUnadjusted odds ratioLarge observational trialsRandom-effects modelOverall beneficial effectObservational trialAnesthetic techniqueAnesthesia techniquesJoint arthroplastyInclusion criteriaTrial designArthroplastyMeta-AnalysisAnesthesiaPotential association