Aymen Alian, MBChB
Associate Professor of AnesthesiologyDownloadHi-Res Photo
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View Doctor ProfileAdditional Titles
Division Chief, Obstetric & Gynecological Anesthesiology
Contact Info
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Division Chief, Obstetric & Gynecological Anesthesiology
Contact Info
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAdditional Titles
Division Chief, Obstetric & Gynecological Anesthesiology
Contact Info
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
About
Titles
Associate Professor of Anesthesiology
Division Chief, Obstetric & Gynecological Anesthesiology
Biography
Dr. Alian is an Associate Professor of Anesthesiology, board certified anesthesiologist, clinical researcher and interim Division Chief for Obstetrics & Gynecologic Anesthesiology. Dr. Alian is a nationally recognized educator and has received several Faculty Awards of Excellence in education and mentorship. His clinical research is dedicated to the investigation of cardiopulmonary and autonomic physiology through the use of non-invasive monitors. Ongoing studies in Dr. Alian’s laboratory focuses on pulse oximetry and cerebral oximetry waveforms as sensitive biomarkers of central hypovolemia during anesthesia-surgery.
Appointments
Anesthesiology
Associate Professor on TermPrimary
Other Departments & Organizations
Education & Training
- Resident
- Yale-New Haven Hospital (2008)
- Intern
- Griffin Hospital (2005)
- MBChB
- Zagazig University (1991)
Research
Overview
Medical Research Interests
Anesthesiology; Laser-Doppler Flowmetry; Plethysmography
ORCID
0000-0002-4810-8155
Research at a Glance
Yale Co-Authors
Frequent collaborators of Aymen Alian's published research.
Publications Timeline
A big-picture view of Aymen Alian's research output by year.
Kirk Shelley, MD/PhD
Kristen L. Fardelmann, MD
Antonio Gonzalez-Fiol, MD
Katherine Kohari, MD, FACOG
Nils Petersen, MD/PhD, MSc
Paul Heerdt, PhD, MD
16Publications
70Citations
Publications
2024
Photoplethysmography Features Correlated with Blood Pressure Changes
Elgendi M, Jost E, Alian A, Fletcher R, Bomberg H, Eichenberger U, Menon C. Photoplethysmography Features Correlated with Blood Pressure Changes. Diagnostics 2024, 14: 2309. PMID: 39451632, PMCID: PMC11506471, DOI: 10.3390/diagnostics14202309.Peer-Reviewed Original ResearchConceptsTemporal domain featuresBlood pressure estimationPPG featuresBlood pressure predictionDomain featuresWearable devicesPhotoplethysmography signalsAcceleration photoplethysmogramPPG signalsPressure estimationPressure predictionPhotoplethysmography's featuresPhotoplethysmographyPredictor of systolic blood pressurePostpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia
van Wingerden A, Katsidoniotaki M, Haghighi N, Almonte C, Martinez H, Valdes E, Castro P, Alian A, Booker W, Bello N, Marshall R, Kougioumtzoglou I, Petersen N, Miller E. Postpartum Blood Pressure Variability and Heart Rate Variability in Preeclampsia. Hypertension 2024, 81: 2510-2519. PMID: 39403810, PMCID: PMC11578794, DOI: 10.1161/hypertensionaha.124.23321.Peer-Reviewed Original ResearchConceptsBlood pressure variabilityChronic hypertensionHeart rate variabilitySuperimposed preeclampsiaBlood pressurePressure variabilityProspective cohort of womenTime-domain heart rate variabilityAssociated with autonomic dysregulationCohort of womenRatio of heart rate variabilityHigh blood pressure variabilityRate variabilityPreeclampsia groupLow-/high-frequency ratioPostpartum patientsPostpartum controlsPreeclampsiaRR interval differencesProspective cohortHigh-frequency heart rate variabilityAutonomic dysregulationPostpartum womenFinger plethysmographyWeeks postpartumGraph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging
Borik S, Wu H, Shelley K, Alian A. Graph connection Laplacian allows for enhanced outcomes of consumer camera based photoplethysmography imaging. Biomedical Signal Processing And Control 2024, 96: 106574. DOI: 10.1016/j.bspc.2024.106574.Peer-Reviewed Original ResearchRecommendations for evaluating photoplethysmography-based algorithms for blood pressure assessment
Elgendi M, Haugg F, Fletcher R, Allen J, Shin H, Alian A, Menon C. Recommendations for evaluating photoplethysmography-based algorithms for blood pressure assessment. Communications Medicine 2024, 4: 140. PMID: 38997447, PMCID: PMC11245506, DOI: 10.1038/s43856-024-00555-2.Peer-Reviewed Original ResearchCitations
2023
A Prospective Cohort Study to Evaluate Needle Passes Using a Portable Ultrasound Device versus Traditional Landmark Approach for Epidural Anesthesia in a Busy Obstetric Tertiary Care Center
Fiol A, Rodriguez P, Zhao X, Gaiser R, Herrera A, Alian A. A Prospective Cohort Study to Evaluate Needle Passes Using a Portable Ultrasound Device versus Traditional Landmark Approach for Epidural Anesthesia in a Busy Obstetric Tertiary Care Center. POCUS Journal 2023, 8: 153-158. PMID: 38099155, PMCID: PMC10721287, DOI: 10.24908/pocus.v8i2.16298.Peer-Reviewed Original ResearchAltmetricConceptsAssessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis
Anakmeteeprugsa S, Gonzalez-Fiol A, Vychodil R, Shelley K, Alian A. Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis. Journal Of Clinical Monitoring And Computing 2023, 38: 293-299. PMID: 37966562, DOI: 10.1007/s10877-023-01098-y.Peer-Reviewed Original ResearchAltmetricConceptsEstimated blood lossBioelectrical impedance analysisBlood lossHealthy volunteersBlood volumeProspective observational studyBody negative pressureSignificant increaseT-testStudent's t-testAcute hemorrhageLBNP protocolLower extremitiesObservational studyHypovolemiaLBNPCompensatory mechanismsPercentage changeReciprocal changesSignificant decreaseBioimpedanceBaselineSignificant correlationMmHgP-valueSignal quality assessment of peripheral venous pressure
Chiu N, Chuang B, Anakmeteeprugsa S, Shelley K, Alian A, Wu H. Signal quality assessment of peripheral venous pressure. Journal Of Clinical Monitoring And Computing 2023, 38: 101-112. PMID: 37917210, DOI: 10.1007/s10877-023-01071-9.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSignal quality indexSignal qualityAdaptive non-harmonic modelSignal quality assessmentLower body negative pressure experimentsHigh qualityPressure experimentsSVM modelWaveformsPVP waveformsPressure waveformPeripheral venous pressure waveformsPVP segmentsOne-subject-out cross validationPowerPractical purposesPressureConvincing potentialContinuous non-invasive hemodynamic monitoring in early onset severe preeclampsia
Ackerman-Banks C, Bhinder J, Eder M, Heerdt P, Sugeng L, Testani J, Alian A, Lipkind H, Velazquez E, Reddy U, Chou J. Continuous non-invasive hemodynamic monitoring in early onset severe preeclampsia. Pregnancy Hypertension 2023, 34: 27-32. PMID: 37783090, DOI: 10.1016/j.preghy.2023.09.003.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsTotal peripheral resistanceCardiac outputSevere preeclampsiaHemodynamic monitoringEarly-onset severe preeclampsiaProspective observational studyOnset severe preeclampsiaContinuous hemodynamic monitoringNon-invasive hemodynamic monitoringEarly preeclampsiaPregnant patientsPeripheral resistanceObservational studyPreeclampsiaLow mean biasDays postpartumNICOMModerate correlationPoor correlationMean biasAntepartumPatientsBaseline rotational thromboelastometry (ROTEM) values in a healthy, diverse obstetric population and parameter changes by pregnancy-induced comorbidities
Fiol A, Yoo J, Yanez D, Fardelmann K, Salimi N, Alian M, Mancini P, Alian A. Baseline rotational thromboelastometry (ROTEM) values in a healthy, diverse obstetric population and parameter changes by pregnancy-induced comorbidities. Baylor University Medical Center Proceedings 2023, 36: 562-571. PMID: 37614857, PMCID: PMC10443986, DOI: 10.1080/08998280.2023.2217534.Peer-Reviewed Original ResearchAltmetricConceptsRotational thromboelastometryCoagulability statusObstetric populationROTEM valuesFIBTEM A10Elevated liver enzymesLow platelets (HELLP) syndromeMaximum clot firmnessClot formation timeBody mass indexPostpartum hemorrhage managementEXTEM A10Recent bleedingCesarean deliveryClot firmnessHypercoagulable profileGestational ageLiver diseasePostpartum hemorrhageRetrospective reviewMass indexBlack raceMaternal ageBlood productsHealthy criteriaUsing the ear photoplethysmographic waveform as an early indicator of central hypovolemia in healthy volunteers utilizing LBNP induced hypovolemia model
Eid A, Elgamal M, Gonzalez-Fiol A, Shelley K, Wu H, Alian A. Using the ear photoplethysmographic waveform as an early indicator of central hypovolemia in healthy volunteers utilizing LBNP induced hypovolemia model. Physiological Measurement 2023, 44: 055008. PMID: 37116503, DOI: 10.1088/1361-6579/acd165.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsLower body negative pressureCentral hypovolemiaHealthy volunteersNon-invasive cardiac output monitorProgressive lower body negative pressureNoninvasive blood pressure monitorBody negative pressureCardiac output monitorBlood pressure monitorPhotoplethysmographic waveformPulse oximetry probeHypoperfusion symptomsSymptomatic subjectsHemodynamic indicesLBNP stageStroke volumeEarly predictorLT groupHypovolemiaEarly stagesPressure monitorWaveform indicesEarly indicatorWaveform morphologySymptoms
Clinical Care
Overview
Clinical Specialties
Anesthesiology; Obstetric Anesthesiology
Fact Sheets
Pain Management for C-Sections
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Board Certifications
Anesthesiology
- Certification Organization
- AB of Anesthesiology
- Original Certification Date
- 2009
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileNews
News
- October 31, 2022
Dr. Christine Won Elected President of Society of Anesthesiology and Sleep Medicine
- February 27, 2018
Dr. Aymen Alian receives two extramural grants to fund his research work.
- November 01, 2017
The Anesthesia department conducted a Ultrasound use for OB Anesthesiology workshop for residents and faculty on 11/05/2017
- January 31, 2017
STA 2017 Annual Meeting: Technology Advancing Perioperative Outcomes
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Mailing Address
Anesthesiology
PO Box 208051, 333 Cedar Street, TMP 3
New Haven, CT 06520-8051
United States
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Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.