Publications

Lumipulse-Measured Cerebrospinal Fluid Biomarkers for the Early Detection of Alzheimer Disease.Safransky M, Groh JR, Blennow K, Zetterberg H, Tripodis Y, Martin B, Weller J, Asken BM, Rabinovici GD, Qiu WWQ, McKee AC, Stein TD, Mez J, Henson RL, Long J, Morris JC, Perrin RJ, Schindler SE, Alosco ML. Neurology. 2024 Dec 10; 2024 Nov 4. PMID: 39496102.
Medial Amygdalar Tau Is Associated With Mood Symptoms in Preclinical Alzheimer's Disease.Li JS, Tun SM, Ficek-Tani B, Xu W, Wang S, Horien CL, Toyonaga T, Nuli SS, Zeiss CJ, Powers AR, Zhao Y, Mormino EC, Fredericks CA. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Dec; 2024 Jul 25. PMID: 39059466.
A Joint Model for Disability, Self-Rated Health, and Mortality Among Medicare Beneficiaries-Differences by Chronic Disease and Race/Ethnicity.Quiñones AR, McAvay G, Vander Wyk B, Han L, Nagel C, Allore HG. J Aging Health. 2024 Dec; 2023 Oct 25. PMID: 37879084.
Comparative lifespan and healthspan of nonhuman primate species common to biomedical research.Huber HF, Ainsworth HC, Quillen EE, Salmon A, Ross C, Azhar AD, Bales K, Basso MA, Coleman K, Colman R, Darusman HS, Hopkins W, Hotchkiss CE, Jorgensen MJ, Kavanagh K, Li C, Mattison JA, Nathanielsz PW, Saputro S, Scorpio DG, Sosa PM, Vallender EJ, Wang Y, Zeiss CJ, Shively CA, Cox LA. Geroscience. 2024 Nov 25; 2024 Nov 25. PMID: 39585646.
Comparative lifespan and healthspan of nonhuman primate species common to biomedical research.Huber HF, Ainsworth HC, Quillen EE, Salmon A, Ross C, Azhar AD, Bales K, Basso MA, Coleman K, Colman R, Darusman HS, Hopkins W, Hotchkiss CE, Jorgensen MJ, Kavanagh K, Li C, Mattison JA, Nathanielsz PW, Saputro S, Scorpio DG, Sosa PM, Vallender EJ, Wang Y, Zeiss CJ, Shively CA, Cox LA. bioRxiv. 2024 Nov 8; 2024 Nov 8. PMID: 39131309.
Prediction and clustering of Alzheimer's disease by race and sex: a multi-head deep-learning approach to analyze irregular and heterogeneous data.Chang CY, Slowiejko D, Win N. Sci Rep. 2024 Nov 4; 2024 Nov 4. PMID: 39496718.
GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia.Shade LMP, Katsumata Y, Abner EL, Aung KZ, Claas SA, Qiao Q, Heberle BA, Brandon JA, Page ML, Hohman TJ, Mukherjee S, Mayeux RP, Farrer LA, Schellenberg GD, Haines JL, Kukull WA, Nho K, Saykin AJ, Bennett DA, Schneider JA, Ebbert MTW, Nelson PT, Fardo DW. Nat Genet. 2024 Nov; 2024 Oct 8. PMID: 39379761.
Self-reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort.Miller AA, Sharp ES, Wang S, Zhao Y, Mecca AP, van Dyck CH, O'Dell RS. Alzheimers Dement. 2024 Nov; 2024 Sep 26. PMID: 39324520.
Validation of a Simplified Tissue-to-Reference Ratio Measurement Using SUVR to Assess Synaptic Density Alterations in Alzheimer Disease with [(11)C]UCB-J PET.Young JJ, O'Dell RS, Naganawa M, Toyonaga T, Chen MK, Nabulsi NB, Huang Y, Cooper E, Miller A, Lam J, Bates K, Ruan A, Nelsen K, Salardini E, Carson RE, van Dyck CH, Mecca AP. J Nucl Med. 2024 Nov 1; 2024 Nov 1. PMID: 39299782.
Levetiracetam prevents Aβ(42) production through SV2a-dependent modulation of App processing in Alzheimer's disease models.Rao NR, DeGulis O, Nomura T, Lee S, Hark TJ, Dynes JC, Dexter EX, Dulewicz M, Ge J, Upadhyay A, Fornasiero EF, Vassar R, Hanrieder J, Contractor A, Savas JN. bioRxiv. 2024 Oct 28; 2024 Oct 28. PMID: 39554163.
Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites.Tong T, Zhu C, Farrell JJ, Khurshid Z, Martin ER, Pericak-Vance MA, Wang LS, Bush WS, Schellenberg GD, Haines JL, Qiu WQ, Lunetta KL, Farrer LA, Zhang X. Alzheimers Res Ther. 2024 Oct 23; 2024 Oct 23. PMID: 39444005.
Aging-dependent loss of functional connectivity in a mouse model of Alzheimer's disease and reversal by mGluR5 modulator.Mandino F, Shen X, Desrosiers-Grégoire G, O'Connor D, Mukherjee B, Owens A, Qu A, Onofrey J, Papademetris X, Chakravarty MM, Strittmatter SM, Lake EMR. Mol Psychiatry. 2024 Oct 18; 2024 Oct 18. PMID: 39424929.
Anatomic Interpretability in Neuroimage Deep Learning: Saliency Approaches for Typical Aging and Traumatic Brain Injury.Guo K, Chaudhari N, Jafar T, Chowdhury N, Bogdan P, Irimia A. Res Sq. 2024 Oct 16; 2024 Oct 16. PMID: 39483910.
NIAGADS: A Comprehensive National Data Repository for Alzheimer's Disease and Related Dementia Genetics and Genomics Research.Kuzma A, Valladares O, Greenfest-Allen E, Nicaretta H, Kirsch M, Ren Y, Katanic Z, White H, Wilk A, Bass L, Brettschneider J, Carter L, Cifello J, Chuang WH, Clark K, Gangadharan P, Haut J, Ho PC, Horng W, Iqbal T, Jin Y, Keskinen P, Rose AL, Moon MK, Manuel J, Qu L, Robbins F, Saravanan N, Sha J, Tate S, Zhao Y, Cantwell L, Gardner J, Chou SY, Tzeng JY, Bush W, Naj A, Kuksa P, Lee WP, Leung YY, Schellenberg G, Wang LS. medRxiv. 2024 Oct 9; 2024 Oct 9. PMID: 39417134.
Cellular Prion Protein Conformational Shift after Liquid-Liquid Phase Separation Regulated by a Polymeric Antagonist and Mutations.Liu Y, Tuttle MD, Kostylev MA, Roseman GP, Zilm KW, Strittmatter SM. J Am Chem Soc. 2024 Oct 9; 2024 Sep 26. PMID: 39326869.
Anatomic Interpretability in Neuroimage Deep Learning: Saliency Approaches for Typical Aging and Traumatic Brain Injury.Guo KH, Chaudhari NN, Jafar T, Chowdhury NF, Bogdan P, Irimia A. Neuroinformatics. 2024 Oct; 2024 Nov 6. PMID: 39503843.
Emergency Department Visits Among Patients With Dementia Before and After Diagnosis.Gettel CJ, Song Y, Rothenberg C, Kitchen C, Gilmore-Bykovskyi A, Fried TR, Brody AA, Nothelle S, Wolff JL, Venkatesh AK. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39401040.
Cognitive dispersion and its functional relevance in behavioral variant frontotemporal dementia and prodromal behavioral variant frontotemporal dementia.Webber TA, Woods SP, Lorkiewicz SA, Yazbeck HW, Schultz ER, Kiselica AM. Neuropsychology. 2024 Oct; 2024 Aug 29. PMID: 39207439.
Association of polygenic risk scores with Alzheimer's disease and plasma biomarkers among Chinese older adults: A community-based study.Hou T, Liu K, Fa W, Liu C, Zhu M, Liang X, Ren Y, Xu S, Wang X, Tang S, Wang Y, Cong L, Tan Q, Du Y, Qiu C. Alzheimers Dement. 2024 Oct; 2024 Aug 22. PMID: 39171679.
CT1812 biomarker signature from a meta-analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease.Lizama BN, Williams C, North HA, Pandey K, Duong D, Di Caro V, Mecca AP, Blennow K, Zetterberg H, Levey AI, Grundman M, van Dyck CH, Caggiano AO, Seyfried NT, Hamby ME. Alzheimers Dement. 2024 Oct; 2024 Aug 21. PMID: 39166791.
Integrative analysis reveals key lysosomal genes as potential therapeutic targets in Alzheimer's disease.Zhu X, Gao J, Qiu C. Metab Brain Dis. 2024 Oct; 2024 Aug 16. PMID: 39150655.
AI-based differential diagnosis of dementia etiologies on multimodal data.Xue C, Kowshik SS, Lteif D, Puducheri S, Jasodanand VH, Zhou OT, Walia AS, Guney OB, Zhang JD, Pham ST, Kaliaev A, Andreu-Arasa VC, Dwyer BC, Farris CW, Hao H, Kedar S, Mian AZ, Murman DL, O'Shea SA, Paul AB, Rohatgi S, Saint-Hilaire MH, Sartor EA, Setty BN, Small JE, Swaminathan A, Taraschenko O, Yuan J, Zhou Y, Zhu S, Karjadi C, Alvin Ang TF, Bargal SA, Plummer BA, Poston KL, Ahangaran M, Au R, Kolachalama VB. Nat Med. 2024 Oct; 2024 Jul 4. PMID: 38965435.
Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer's disease: a multi-tracer PET study.Salardini E, O'Dell RS, Tchorz E, Nabulsi NB, Huang Y, Carson RE, van Dyck CH, Mecca AP. bioRxiv. 2024 Sep 24; 2024 Sep 24. PMID: 39386453.
Association of Seizure Control With Cognition in People With Normal Cognition and Mild Cognitive Impairment.Zawar I, Kapur J, Mattos MK, Aldridge CM, Manning C, Quigg M. Neurology. 2024 Sep 24; 2024 Aug 22. PMID: 39173101.
Linkage Disequilibrium-Informed Deep Learning Framework to Identify Genetic Loci for Alzheimer's Disease Using Whole Genome Sequencing Data.Jo T, Bice P, Nho K, Saykin AJ. medRxiv. 2024 Sep 22; 2024 Sep 22. PMID: 39371140.
Repetitive Mild Closed-Head Injury Induced Synapse Loss and Increased Local BOLD-fMRI Signal Homogeneity.Markicevic M, Mandino F, Toyonaga T, Cai Z, Fesharaki-Zadeh A, Shen X, Strittmatter SM, Lake EMR. J Neurotrauma. 2024 Sep 20; 2024 Sep 20. PMID: 39096127.
Association of education attainment, smoking status, and alcohol use disorder with dementia risk in older adults: a longitudinal observational study.Tang H, Shaaban CE, DeKosky ST, Smith GE, Hu X, Jaffee M, Salloum RG, Bian J, Guo J. Alzheimers Res Ther. 2024 Sep 18; 2024 Sep 18. PMID: 39294787.
Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism.Takahashi H, Perez-Canamas A, Lee CW, Ye H, Han X, Strittmatter SM. Commun Biol. 2024 Sep 5; 2024 Sep 5. PMID: 39237682.
Neuropsychiatric symptoms: Risk factor or disease marker? A study of structural imaging biomarkers of Alzheimer's disease and incident cognitive decline.Guan DX, Rehman T, Nathan S, Durrani R, Potvin O, Duchesne S, Pike GB, Smith EE, Ismail Z. Hum Brain Mapp. 2024 Sep. PMID: 39254167.
Use of alpha-adrenergic antagonists for lower urinary tract symptoms is not associated with worsening cognitive function.Berto FG, McClure JA, Campbell J, Welk B. Neurourol Urodyn. 2024 Sep; 2024 May 27. PMID: 38803218.
Relationship between neuroimaging and cognition in frontotemporal dementia: An FDG-PET and structural MRI study.Cayir S, Volpi T, Toyonaga T, Gallezot JD, Yang Y, Sadabad FE, Mulnix T, Mecca AP, Fesharaki-Zadeh A, Matuskey D. J Neuroimaging. 2024 Sep-Oct; 2024 Apr 26. PMID: 38676301.
Causal Association between Circulating Metabolites and Dementia: A Mendelian Randomization Study.Li HM, Qiu CS, Du LY, Tang XL, Liao DQ, Xiong ZY, Lai SM, Huang HX, Kuang L, Zhang BY, Li ZH. Nutrients. 2024 Aug 28; 2024 Aug 28. PMID: 39275195.
The Montreal Cognitive Assessment: Norms and Reliable Change Indices for Standard and MoCA-22 Administrations.Ratcliffe LN, Hale AC, McDonald T, Hewitt KC, Nguyen CM, Spencer RJ, Loring DW. Arch Clin Neuropsychol. 2024 Aug 24. PMID: 38441951.
Development and Validity of Norms for Cognitive Dispersion on the Uniform Data Set 3.0 Neuropsychological Battery.Kiselica AM, Kaser AN, Weitzner DS, Mikula CM, Boone A, Woods SP, Wolf TJ, Webber TA. Arch Clin Neuropsychol. 2024 Aug 24. PMID: 38364295.
Dementia Risk Scores, APOE, and risk of Alzheimer disease: one size does not fit all.Andrews SJ, Boeriu AI, Belloy ME, Renton AE, Fulton-Howard B, Brenowitz WD, Yaffe K. medRxiv. 2024 Aug 16; 2024 Aug 16. PMID: 38746455.
Neuropsychiatric symptom burden in early-onset and late-onset Alzheimer's disease as a function of age.Polsinelli AJ, Johnson S, Crouch A, Lane KA, Pena-Garcia A, Hammers DB, Wang S, Gao S, Apostolova LG. Alzheimers Dement. 2024 Aug; 2024 Jul 3. PMID: 38958543.
Longitudinal Patterns of Systolic Blood Pressure, Diastolic Blood Pressure, Cardiorespiratory Fitness, and Their Association With Dementia Risk: The HUNT Study.Lerfald M, Allore H, Nilsen TIL, Eldholm RS, Martinez-Velilla N, Selbæk G, Ernstsen L. J Gerontol A Biol Sci Med Sci. 2024 Aug 1. PMID: 38894618.
Commentary on "Study Partner Report of Apathy in Older Adults is Associated With AD Biomarkers: Findings From the Harvard Aging Brain Study".Khasnavis S, O'Dell RS, van Dyck CH, Mecca AP. Am J Geriatr Psychiatry. 2024 Aug; 2024 Apr 4. PMID: 38658231.
Chemical entity normalization for successful translational development of Alzheimer's disease and dementia therapeutics.Mullin S, McDougal R, Cheung KH, Kilicoglu H, Beck A, Zeiss CJ. J Biomed Semantics. 2024 Jul 31; 2024 Jul 31. PMID: 39080729.
Late-Life Blood Pressure and Cerebral Amyloid Angiopathy: Findings from the U.S. National Alzheimer's Coordinating Center Uniform Dataset.Sin MK, Dowling NM, Roseman JM, Ahmed A, Zamrini E. Neurol Int. 2024 Jul 29; 2024 Jul 29. PMID: 39195563.
Single-cell analysis reveals transcriptional dynamics in healthy primary parathyroid tissue.Venkat A, Carlino MJ, Lawton BR, Prasad ML, Amodio M, Gibson CE, Zeiss CJ, Youlten SE, Krishnaswamy S, Krause DS. Genome Res. 2024 Jul 23; 2024 Jul 23. PMID: 38977309.
Racial/ethnic differences in neuropsychiatric disturbances associated with incident dementia.Wise EA, Yan H, Oh E, Leoutsakos JM. Alzheimers Dement (Amst). 2024 Jul-Sep; 2024 Jul 5. PMID: 38974877.
Field-of-view extension for brain diffusion MRI via deep generative models.Gao C, Bao S, Kim ME, Newlin NR, Kanakaraj P, Yao T, Rudravaram G, Huo Y, Moyer D, Schilling K, Kukull WA, Toga AW, Archer DB, Hohman TJ, Landman BA, Li Z. J Med Imaging (Bellingham). 2024 Jul; 2024 Aug 24. PMID: 39185475.
The Association of Gabapentin Initiation with Cognitive and Behavioral Changes in Older Adults with Cognitive Impairment: A Retrospective Cohort Study.Oh G, Moga DC, Fardo DW, Harp JP, Abner EL. Drugs Aging. 2024 Jul; 2024 Jul 9. PMID: 38980643.
Unraveling the multiple chronic conditions patterns among people with Alzheimer's disease and related dementia: A machine learning approach to incorporate synergistic interactions.Yew PY, Devera R, Liang Y, Khalifa RAE, Sun J, Chi NC, Chou YC, Tonellato PJ, Chi CL. Alzheimers Dement. 2024 Jul; 2024 Jun 11. PMID: 38859733.
Do we all do the same things? Applicability of daily activities at the intersection of demographics.González DA, Benge JF. Neuropsychology. 2024 Jul; 2024 May 16. PMID: 38753380.
Changes in Cognitive Function After Kidney Transplantation: A Longitudinal Cohort Study.Gupta A, Mahnken JD, Bernal J, Sharma P, Lepping RJ, Montgomery RN, Johnson DK, Parks A, Burns JM, Drew DA, Sarnak MJ, Brooks WM. Am J Kidney Dis. 2024 Jul; 2024 Feb 28. PMID: 38423160.
Assessment of disparities in timely diagnosis and comprehensive workup of cognitive impairment between English and Spanish speakers.Silva-Rudberg JA, Carrión CI, Pérez-Palmer N, Li J, Mehta SK, Diab NS, Mecca AP, O'Dell RS. Am J Geriatr Psychiatry. 2024 Jul; 2024 Feb 1. PMID: 38336573.
Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004-2019).Chen S, Underwood BR, Cardinal RN, Chen X, Chen S, Amin J, Jin H, Huang J, Mueller C, Yan LL, Brayne C, Kuper H. BMC Med. 2024 Jun 26; 2024 Jun 26. PMID: 38926751.
Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer's Coordinating Center database.Woodworth DC, Nguyen KM, Sordo L, Scambray KA, Head E, Kawas CH, Corrada MM, Nelson PT, Sajjadi SA. Acta Neuropathol. 2024 Jun 19; 2024 Jun 19. PMID: 38896163.
Sex, racial, and APOE-ε4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease.Peterson A, Sathe A, Zaras D, Yang Y, Durant A, Deters KD, Shashikumar N, Pechman KR, Kim ME, Gao C, Khairi NM, Li Z, Yao T, Huo Y, Dumitrescu L, Gifford KA, Wilson JE, Cambronero F, Risacher SL, Beason-Held LL, An Y, Arfanakis K, Erus G, Davatzikos C, Tosun D, Toga AW, Thompson PM, Mormino EC, Zhang P, Schilling K, Albert M, Kukull W, Biber SA, Landman BA, Johnson SC, Schneider J, Barnes LL, Bennett DA, Jefferson AL, Resnick SM, Saykin AJ, Hohman TJ, Archer DB. bioRxiv. 2024 Jun 12; 2024 Jun 12. PMID: 38915636.
Medial amygdalar tau is associated with anxiety symptoms in preclinical Alzheimer's disease.Li JS, Tun SM, Ficek-Tani B, Xu W, Wang S, Horien CL, Toyonaga T, Nuli SS, Zeiss CJ, Powers AR, Zhao Y, Mormino EC, Fredericks CA. bioRxiv. 2024 Jun 3; 2024 Jun 3. PMID: 38895308.
Adverse effects of methylphenidate for apathy in patients with Alzheimer's disease (ADMET2 trial).Zeng L, Perin J, Gross AL, Shade D, Lanctôt KL, Lerner AJ, Mintzer JE, Brawman-Mintzer O, Padala PR, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Herrmann N, Rosenberg PB. Int J Geriatr Psychiatry. 2024 Jun. PMID: 38858522.
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.Wagemann O, Liu H, Wang G, Shi X, Bittner T, Scelsi MA, Farlow MR, Clifford DB, Supnet-Bell C, Santacruz AM, Aschenbrenner AJ, Hassenstab JJ, Benzinger TLS, Gordon BA, Coalier KA, Cruchaga C, Ibanez L, Perrin RJ, Xiong C, Li Y, Morris JC, Lah JJ, Berman SB, Roberson ED, van Dyck CH, Galasko D, Gauthier S, Hsiung GR, Brooks WS, Pariente J, Mummery CJ, Day GS, Ringman JM, Mendez PC, St George-Hyslop P, Fox NC, Suzuki K, Okhravi HR, Chhatwal J, Levin J, Jucker M, Sims JR, Holdridge KC, Proctor NK, Yaari R, Andersen SW, Mancini M, Llibre-Guerra J, Bateman RJ, McDade E. JAMA Neurol. 2024 Jun 1. PMID: 38683602.
Predicting Progression From Mild Cognitive Impairment to Alzheimer's Dementia With Adversarial Attacks.Baytas IM. IEEE J Biomed Health Inform. 2024 Jun; 2024 Jun 6. PMID: 38507374.
The Relationship Between First Presenting Neuropsychiatric Symptoms in Older Adults and Autopsy-Confirmed Memory Disorders.Shaw JS, Leoutsakos JM, Rosenberg PB. Am J Geriatr Psychiatry. 2024 Jun; 2024 Jan 17. PMID: 38296755.
Cognitive trajectories preluding the onset of different dementia entities: a descriptive longitudinal study using the NACC database.Liampas I, Dimitriou N, Siokas V, Messinis L, Nasios G, Dardiotis E. Aging Clin Exp Res. 2024 May 23; 2024 May 23. PMID: 38780681.
Mental-somatic multimorbidity in trajectories of cognitive function for middle-aged and older adults.Chen S, Nagel CL, Liu R, Botoseneanu A, Allore HG, Newsom JT, Thielke S, Kaye J, Quiñones AR. PLoS One. 2024; 2024 May 14. PMID: 38743678.
Updated safety results from phase 3 lecanemab study in early Alzheimer's disease.Honig LS, Sabbagh MN, van Dyck CH, Sperling RA, Hersch S, Matta A, Giorgi L, Gee M, Kanekiyo M, Li D, Purcell D, Dhadda S, Irizarry M, Kramer L. Alzheimers Res Ther. 2024 May 10; 2024 May 10. PMID: 38730496.
BERNN: Enhancing classification of Liquid Chromatography Mass Spectrometry data with batch effect removal neural networks.Pelletier SJ, Leclercq M, Roux-Dalvai F, de Geus MB, Leslie S, Wang W, Lam TT, Nairn AC, Arnold SE, Carlyle BC, Precioso F, Droit A. Nat Commun. 2024 May 6; 2024 May 6. PMID: 38710683.
Association of Heart Failure With Cognitive Decline and Development of Mild Cognitive Impairment and Dementia.Jung M, Apostolova LG, Gao S, Burney HN, Lai D, Saykin AJ, Pressler SJ. J Cardiovasc Nurs. 2024 May-Jun 01. PMID: 39137265.
Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study.Wisch JK, McKay NS, Boerwinkle AH, Kennedy J, Flores S, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, O'Bryant SE, Price JC, Laymon CM, Krinsky-McHale SJ, Lai F, Rosas HD, Hartley SL, Zaman S, Lott IT, Tudorascu D, Zammit M, Brickman AM, Lee JH, Bird TD, Cohen A, Chrem P, Daniels A, Chhatwal JP, Cruchaga C, Ibanez L, Jucker M, Karch CM, Day GS, Lee JH, Levin J, Llibre-Guerra J, Li Y, Lopera F, Roh JH, Ringman JM, Supnet-Bell C, van Dyck CH, Xiong C, Wang G, Morris JC, McDade E, Bateman RJ, Benzinger TLS, Gordon BA, Ances BM. Lancet Neurol. 2024 May. PMID: 38631766.
Examining the non-linear effects of education on Alzheimer's and non-Alzheimer's disease: Sex-stratified analysis of 17,671 older persons.Liew TM, Ang LC. Soc Sci Med. 2024 May; 2024 Apr 4. PMID: 38598986.
Data-driven classification of cognitively normal and mild cognitive impairment subtypes predicts progression in the NACC dataset.Edmonds EC, Thomas KR, Rapcsak SZ, Lindemer SL, Delano-Wood L, Salmon DP, Bondi MW. Alzheimers Dement. 2024 May; 2024 Apr 4. PMID: 38574399.
Robust reference group normative data for neuropsychological tests accounting for primary language use in Asian American older adults.Kapoor A, Ho JK, Jang JY, Nation DA. J Int Neuropsychol Soc. 2024 May; 2024 Mar 1. PMID: 38425303.
Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer's disease models.Guan XJ, Deng ZQ, Liu J, Su CF, Tong BC, Zhu Z, Sreenivasmurthy SG, Kan YX, Lu KJ, Chu CP, Pi RB, Cheung KH, Iyaswamy A, Song JX, Li M. Acta Pharmacol Sin. 2024 May; 2024 Jan 15. PMID: 38225393.
Sleep Disorders and Cognitive Aging Among Cognitively Impaired Versus Unimpaired Older Adults.Lee S, Nelson ME, Hamada F, Wallace ML, Andel R, Buxton OM, Almeida DM, Lyketsos C, Small BJ. Gerontologist. 2024 May 1. PMID: 37944004.
The Role of Genomic-Informed Risk Assessments in Predicting Dementia Outcomes.Andrews SJ, Jonson C, Fulton-Howard B, Renton AE, Yokoyama JS, Yaffe K. medRxiv. 2024 Apr 30; 2024 Apr 30. PMID: 38903124.
Frailty trajectories preceding dementia: an individual-level analysis of four cohort studies in the United States and United Kingdom.Ward D, Flint J, Littlejohns T, Foote I, Canevelli M, Wallace L, Gordon E, Llewellyn D, Ranson J, Hubbard R, Rockwood K, Stolz E. Res Sq. 2024 Apr 29; 2024 Apr 29. PMID: 38746437.
Cerebral perivascular spaces as predictors of dementia risk and accelerated brain atrophy.Barisano G, Iv M, Choupan J, Hayden-Gephart M. medRxiv. 2024 Apr 26; 2024 Apr 26. PMID: 38712073.
The Role of X Chromosome in Alzheimer's Disease Genetics.Belloy ME, Guen YL, Stewart I, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, Gaziano JM, Logue M, Napolioni V, Greicius MD. medRxiv. 2024 Apr 23; 2024 Apr 23. PMID: 38712163.
Mapping of Alzheimer's disease related data elements and the NIH Common Data Elements.Hao X, Abeysinghe R, Zheng F, Schulz PE, Cui L. BMC Med Inform Decis Mak. 2024 Apr 19; 2024 Apr 19. PMID: 38641585.
Optimal conditions for carrying out trypsin digestions on complex proteomes: From bulk samples to single cells.Mansuri MS, Bathla S, Lam TT, Nairn AC, Williams KR. J Proteomics. 2024 Apr 15; 2024 Feb 5. PMID: 38325732.
Drivers of Memory Loss Underreport in Mild Cognitive Impairment Due to Alzheimer Versus Vascular Disease.Briggs AQ, Ouedraogo Tall S, Boza-Calvo C, Bernard MA, Bubu OM, Masurkar AV. Alzheimer Dis Assoc Disord. 2024 Apr-Jun 01; 2024 May 17. PMID: 38755756.
DeepN4: Learning N4ITK Bias Field Correction for T1-weighted Images.Kanakaraj P, Yao T, Cai LY, Lee HH, Newlin NR, Kim ME, Gao C, Pechman KR, Archer D, Hohman T, Jefferson A, Beason-Held LL, Resnick SM, Garyfallidis E, Anderson A, Schilling KG, Landman BA, Moyer D. Neuroinformatics. 2024 Apr; 2024 Mar 25. PMID: 38526701.
Genetic associations with dementia-related proteinopathy: Application of item response theory.Katsumata Y, Fardo DW, Shade LMP, Wu X, Karanth SD, Hohman TJ, Schneider JA, Bennett DA, Farfel JM, Gauthreaux K, Mock C, Kukull WA, Abner EL, Nelson PT. Alzheimers Dement. 2024 Apr; 2024 Mar 9. PMID: 38460116.
Nanoscale imaging of pT217-tau in aged rhesus macaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early-stage neurodegeneration.Datta D, Perone I, Wijegunawardana D, Liang F, Morozov YM, Arellano J, Duque A, Xie Z, van Dyck CH, Joyce MKP, Arnsten AFT. Alzheimers Dement. 2024 Apr; 2024 Mar 6. PMID: 38445818.
Investigating the impact of hypertension with and without diabetes on Alzheimer's disease risk: A clinico-pathological study.Ruthirakuhan M, Swardfager W, Xiong L, MacIntosh BJ, Rabin JS, Lanctôt KL, Ottoy J, Ramirez J, Keith J, Black SE. Alzheimers Dement. 2024 Apr; 2024 Feb 29. PMID: 38425134.
Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease.Wang G, Li Y, Xiong C, Benzinger TLS, Gordon BA, Hassenstab J, Aschenbrenner AJ, McDade E, Clifford DB, Libre-Guerra JJ, Shi X, Mummery CJ, van Dyck CH, Lah JJ, Honig LS, Day G, Ringman JM, Brooks WS, Fox NC, Suzuki K, Levin J, Jucker M, Delmar P, Bittner T, Bateman RJ. Alzheimers Dement. 2024 Apr; 2024 Feb 23. PMID: 38400532.
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S. Alzheimers Dement. 2024 Apr; 2024 Feb 21. PMID: 38380866.
Depression, Vascular Burden, and Dementia Prevalence in Late Middle-Aged and Older Black Adults.Levy SA, Misiura MB, Grant JG, Adrien TV, Taiwo Z, Armstrong R, Dotson VM. J Gerontol B Psychol Sci Soc Sci. 2024 Apr 1. PMID: 38374692.
Lewy body pathology modifies risk factors for cerebral amyloid angiopathy when comorbid with Alzheimer's disease pathology.Pillai JA, Bena J, Tousi B, Rothenberg K, Keene CD, Leverenz JB. Alzheimers Dement. 2024 Apr; 2024 Feb 14. PMID: 38353367.
COVID-19 pandemic's relationship with enrollment at US Alzheimer's Disease Research Centers.Shaaban CE, Lin HS, Terry M, Ren D, Lingler JH. Alzheimers Dement. 2024 Apr; 2024 Feb 1. PMID: 38298163.
Reliability and validity of the Montreal Cognitive Assessment's auditory items (MoCA-22).Lord AR, Amitrano NR, González DA. Clin Neuropsychol. 2024 Apr; 2023 Sep 24. PMID: 37743611.
Informant sex/gender moderates associations between reported functioning and memory performance in Mexican American adults.Graves LV, Beacham D, Sawitzky N, Lozano J, Weberg M, Reyes K, Vergonia L, Santana A, Hernandez E, Sarsar D, Conaway Z. Clin Neuropsychol. 2024 Apr; 2023 Aug 12. PMID: 37571992.
Difference of Cerebrospinal Fluid Biomarkers and Neuropsychiatric Symptoms Profiles among Normal Cognition, Mild Cognitive Impairment, and Dementia Patient.Hsu CC, Wang SI, Lin HC, Lin ES, Yang FP, Chang CM, Wei JC. Int J Mol Sci. 2024 Mar 31; 2024 Mar 31. PMID: 38612729.
Synaptic density patterns in early Alzheimer's disease assessed by independent component analysis.Fang XT, Raval NR, O'Dell RS, Naganawa M, Mecca AP, Chen MK, van Dyck CH, Carson RE. Brain Commun. 2024; 2024 Mar 26. PMID: 38601916.
Disentangling and quantifying the relative cognitive impact of concurrent mixed neurodegenerative pathologies.Maldonado-Díaz C, Hiya S, Yokoda RT, Farrell K, Marx GA, Kauffman J, Daoud EV, Gonzales MM, Parker AS, Canbeldek L, Kulumani Mahadevan LS, Crary JF, White CL 3rd, Walker JM, Richardson TE. Acta Neuropathol. 2024 Mar 23; 2024 Mar 23. PMID: 38520489.
Impact of incidental synucleinopathy in mild cognitive impairment due to Alzheimer disease.Shriram J, Malek-Ahmadi M, Irwin C, Sabbagh M. J Neuropathol Exp Neurol. 2024 Mar 20. PMID: 38345347.
Informant characteristics are associated with the Clinical Dementia Rating Sum of Boxes scores in the Alzheimer's Disease patients participating in the National Alzheimer's Coordinating Center Uniform Data Set.Vargas-Gonzalez JC, Chadha AS, Castro-Aldrete L, Ferretti MT, Tartaglia C. Res Sq. 2024 Mar 15; 2024 Mar 15. PMID: 38559129.
Genome-wide association studies identify novel loci in rapidly progressive Alzheimer's disease.Wang P, Lynn A, Miskimen K, Song YE, Wisniewski T, Cohen M, Appleby BS, Safar JG, Haines JL. Alzheimers Dement. 2024 Mar; 2024 Jan 7. PMID: 38184787.
Statistical learning in epilepsy: Behavioral and anatomical mechanisms in the human brain.Aljishi A, Sherman BE, Huberdeau DM, Obaid S, Khan K, Lamsam L, Zibly Z, Sivaraju A, Turk-Browne NB, Damisah EC. Epilepsia. 2024 Mar; 2024 Jan 3. PMID: 38116686.
Retention of American Indian and Alaska Native participants in the National Alzheimer's Coordinating Center Uniform Data Set.Conniff KR, Grill JD, Gillen DL. Alzheimers Dement. 2024 Mar; 2023 Dec 5. PMID: 38053483.
Multimorbidity, cognitive phenotypes, and Alzheimer's disease plasma biomarkers in older adults: A population-based study.Ren Y, Li Y, Tian N, Liu R, Dong Y, Hou T, Liu C, Han X, Han X, Wang L, Vetrano DL, Ngandu T, Marengoni A, Kivipelto M, Wang Y, Cong L, Du Y, Qiu C. Alzheimers Dement. 2024 Mar; 2023 Dec 2. PMID: 38041805.
Machine learning models identify predictive features of patient mortality across dementia types.Zhang J, Song L, Miller Z, Chan KCG, Huang KL. Commun Med (Lond). 2024 Feb 28; 2024 Feb 28. PMID: 38418871.
Geospatial environmental complexity, spatial brain volume, and spatial behavior across the Alzheimer's disease spectrum.Shin N, Rodrigue KM, Yuan M, Kennedy KM. Alzheimers Dement (Amst). 2024 Jan-Mar; 2024 Feb 22. PMID: 38390561.
Profiles of subgingival microbiomes and gingival crevicular metabolic signatures in patients with amnestic mild cognitive impairment and Alzheimer's disease.Qiu C, Zhou W, Shen H, Wang J, Tang R, Wang T, Xie X, Hong B, Ren R, Wang G, Song Z. Alzheimers Res Ther. 2024 Feb 19; 2024 Feb 19. PMID: 38373985.
Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.Takahashi H, Bhagwagar S, Nies SH, Ye H, Han X, Chiasseu MT, Wang G, Mackenzie IR, Strittmatter SM. Nat Commun. 2024 Feb 16; 2024 Feb 16. PMID: 38365772.
The Relationship of Cerebrospinal Fluid Biomarkers and Cognitive Performance in Frontotemporal Dementia.Cayir S, Sadabad FE, Mecca A, Matuskey D, Zadeh AF. Res Sq. 2024 Feb 13; 2024 Feb 13. PMID: 38410483.
Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters.Di Pietro C, Haberman AM, Lindenbach BD, Smith PC, Bruscia EM, Allore HG, Vander Wyk B, Tyagi A, Zeiss CJ. Viruses. 2024 Feb 3; 2024 Feb 3. PMID: 38400021.