2010
Locomotion and Self-Administration Induced by Cocaine in 129/OlaHsd Mice Lacking Galanin
Brabant C, Kuschpel AS, Picciotto MR. Locomotion and Self-Administration Induced by Cocaine in 129/OlaHsd Mice Lacking Galanin. Behavioral Neuroscience 2010, 124: 828-838. PMID: 21038934, PMCID: PMC3058554, DOI: 10.1037/a0021221.Peer-Reviewed Original ResearchConceptsGal KO miceCocaine-induced hyperactivityGalanin receptor agonistCocaine-induced hyperlocomotionSpontaneous motor activityGalanin knockout miceEffects of cocaineDrug takersDoses of cocaineDrugs of abuseSelf-administer cocaineGalanin systemReceptor agonistLocomotor effectsKnockout miceGalaninIntravenous cocaineMotor activityFixed ratio scheduleSelf-AdministrationGenetic deletionMiceCocaineDifferent schedulesRatio schedule
2006
Cocaine self-administration and locomotor sensitization are not altered in CART knockout mice
Steiner RC, Hsiung HM, Picciotto MR. Cocaine self-administration and locomotor sensitization are not altered in CART knockout mice. Behavioural Brain Research 2006, 171: 56-62. PMID: 16621045, DOI: 10.1016/j.bbr.2006.03.022.Peer-Reviewed Original ResearchConceptsKnockout miceLocomotor sensitizationCocaine-induced locomotor sensitizationAmphetamine-regulated transcriptEffects of psychostimulantsRange of dosesAcute cocaineBone resorptionAmphetamine injectionsNucleus accumbensIntravenous cocaineIntact animalsMiceCocaineSchedule of reinforcementInsulin regulationCART geneSensitizationWild-type siblingsPhysiological functionsRegulatory roleStriatumAccumbensPsychostimulantsRats