2021
Visual trajectories and risk of physical and cognitive impairment among older Chinese adults
Cao G, Wang K, Han L, Zhang Q, Yao S, Chen Z, Huang Z, Luo Y, Hu Y, Xu B. Visual trajectories and risk of physical and cognitive impairment among older Chinese adults. Journal Of The American Geriatrics Society 2021, 69: 2877-2887. PMID: 34111310, DOI: 10.1111/jgs.17311.Peer-Reviewed Original ResearchConceptsOlder Chinese adultsIADL disabilityCognitive impairmentChinese adultsADL disabilityFunctional impairmentCognitive functionMini-Mental State Examination scoreProgressive declineChinese Longitudinal Healthy Longevity SurveyState Examination scoreModerate declineGroup-based trajectory modelsKatz scaleLawton scalePotential confoundersLongevity SurveyImpairmentDecline trajectoriesChinese versionDisabilityLongitudinal studyAdultsRiskExamination scores
2020
Cohort Profile: The Precipitating Events Project (PEP Study)
Gill T, Han L, Gahbauer EA, Leo-Summers L, Murphy TE. Cohort Profile: The Precipitating Events Project (PEP Study). The Journal Of Nutrition, Health & Aging 2020, 24: 438-444. PMID: 32242212, PMCID: PMC7322244, DOI: 10.1007/s12603-020-1341-4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPrecipitating Events ProjectPEP studyComprehensive home-based assessmentsEpidemiology of disabilityAge 70 yearsHealth care utilizationGreater New HavenLarge health planParticipant-level dataHome-based assessmentEnd of lifeCare utilizationDeath certificatesMedicare claimsDepressive symptomsOngoing longitudinal studyDisabling processEligible membersOlder personsHealth plansLongitudinal studyMethodologic researchCompletion ratesOriginal reportQualified investigators
2019
Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study
Yao SS, Cao GY, Han L, Chen ZS, Huang ZT, Gong P, Hu Y, Xu B. Prevalence and Patterns of Multimorbidity in a Nationally Representative Sample of Older Chinese: Results From the China Health and Retirement Longitudinal Study. The Journals Of Gerontology Series A 2019, 75: 1974-1980. PMID: 31406983, DOI: 10.1093/gerona/glz185.Peer-Reviewed Original ResearchConceptsPatterns of multimorbidityPrevalence of multimorbidityMultimorbidity patternsRetirement Longitudinal StudyOlder ChineseChina HealthPopulation-based studyDemographic characteristicsIndividual chronic diseasesLongitudinal studyCommon multimorbidity patternsLogistic regression modelsParticipants' demographic characteristicsNationally Representative SampleEntire cohortPotential confoundersChronic diseasesRepresentative sampleMultimorbidityAlcohol consumptionMemory-related diseasesUrban-rural differencesPrevalenceInterventional implicationsResidential region
2018
MULTIMORBIDITY PATTERNS AND ASSOCIATIONS WITH FUNCTIONAL OUTCOMES AMONG OLDER CHINESE
Xu B, Han L, Li M, Cao G, Yao S, Hu Y. MULTIMORBIDITY PATTERNS AND ASSOCIATIONS WITH FUNCTIONAL OUTCOMES AMONG OLDER CHINESE. Innovation In Aging 2018, 2: 498-498. PMCID: PMC6228077, DOI: 10.1093/geroni/igy023.1855.Peer-Reviewed Original ResearchChronic conditionsMultimorbidity patternsFunctional outcomeHandgrip strengthChina HealthPatterns of multimorbidityMultiple chronic conditionsIntegrated care planMaximum handgrip strengthHandgrip strength valuesRetirement Longitudinal StudyLower cognitive scoresOlder patientsFunctional statusOverall prevalenceCare plansElevated riskNutrition SurveyClinical problemClinical decisionChinese populationCognitive functionMultimorbidityCognitive scoresLongitudinal studyPrognostic Effect of Changes in Physical Function Over Prior Year on Subsequent Mortality and Long‐Term Nursing Home Admission
Gill TM, Han L, Gahbauer EA, Leo‐Summers L, Allore HG. Prognostic Effect of Changes in Physical Function Over Prior Year on Subsequent Mortality and Long‐Term Nursing Home Admission. Journal Of The American Geriatrics Society 2018, 66: 1587-1591. PMID: 29719039, PMCID: PMC6133765, DOI: 10.1111/jgs.15399.Peer-Reviewed Original ResearchConceptsLong-term nursing home admissionNursing home admissionHome admissionPhysical functionDisability scoresPrognostic effectDaily livingPrior yearCommunity-living personsRisk of deathUseful prognostic informationProspective longitudinal studyAdverse outcomesPrognostic informationMultivariable modelInstrumental activitiesSubsequent mortalityAdmissionBivariate predictorsSubsequent outcomesMonthsDifferent intervalsComprehensive assessmentDeathLongitudinal study
2017
The subsequent course of disability in older persons discharged to a skilled nursing facility after an acute hospitalization
Liu Z, Han L, Leo-Summers L, Gahbauer EA, Allore HG, Gill TM. The subsequent course of disability in older persons discharged to a skilled nursing facility after an acute hospitalization. Experimental Gerontology 2017, 97: 73-79. PMID: 28782593, PMCID: PMC5793887, DOI: 10.1016/j.exger.2017.08.004.Peer-Reviewed Original ResearchConceptsElective major surgerySkilled nursing facilitiesMajor surgeryAcute hospitalizationCritical illnessOlder personsDisability burdenNursing facilitiesSubsequent courseCommunity-living personsRate ratioType of hospitalizationIndex admissionSecondary outcomesSNF admissionFunctional outcomeMore admissionsHospitalizationSurgeryAdmissionIllnessLongitudinal studyDisabilityMobility activitiesExclusive groups
2013
Comparisons Between Older Men and Women in the Trajectory and Burden of Disability Over the Course of Nearly 14 Years
Gill TM, Gahbauer EA, Lin H, Han L, Allore HG. Comparisons Between Older Men and Women in the Trajectory and Burden of Disability Over the Course of Nearly 14 Years. Journal Of The American Medical Directors Association 2013, 14: 280-286. PMID: 23294968, PMCID: PMC3615123, DOI: 10.1016/j.jamda.2012.11.011.Peer-Reviewed Original ResearchConceptsBurden of disabilityOlder menModerate disabilityGender differencesWorse disabilityDisability trajectoriesClinical covariatesDaily livingOlder womenBaseline levelsHigh mortalityGreater burdenSevere disabilityMonthly interviewsLife course approachWomenMild disabilityDisabilityBasic activitiesLongitudinal studyMenMobility activitiesHigh rateHigher initial levelsBurden
2011
The Relationship Between Intervening Hospitalizations and Transitions Between Frailty States
Gill TM, Gahbauer EA, Han L, Allore HG. The Relationship Between Intervening Hospitalizations and Transitions Between Frailty States. The Journals Of Gerontology Series A 2011, 66A: 1238-1243. PMID: 21852286, PMCID: PMC3193526, DOI: 10.1093/gerona/glr142.Peer-Reviewed Original ResearchConceptsFrailty stateGreater frailtyLess frailtyFrail stateOlder personsAdjusted hazard ratioCommunity-living personsLow physical activitySlow walking speedProspective longitudinal studyFrailty statusHazard ratioMuscle weaknessHospitalizationPhysical activityNonfrailPrefrailFrailtyWalking speedsMonthsLongitudinal studyFrailAdverse consequencesExposure rateConsistent effect
2010
Treatment of Death in the Analysis of Longitudinal Studies of Gerontological Outcomes
Murphy TE, Han L, Allore HG, Peduzzi PN, Gill TM, Lin H. Treatment of Death in the Analysis of Longitudinal Studies of Gerontological Outcomes. The Journals Of Gerontology Series A 2010, 66A: 109-114. PMID: 21030467, PMCID: PMC3011957, DOI: 10.1093/gerona/glq188.Peer-Reviewed Original ResearchConceptsFunctional disabilityOlder study populationStudy populationLongitudinal studyOlder personsCommunity-living older personsHealthy survivor effectLongitudinal outcomesSurvivor effectFunctional abilityDeathOutcomesDisabilityLongitudinal modelingTreatmentInformative censoringNoninformative censoringRapid declineStrong relationshipCohortPopulationPersonsStudySurvivorsDecedentsTrajectories of Disability in the Last Year of Life
Gill TM, Gahbauer EA, Han L, Allore HG. Trajectories of Disability in the Last Year of Life. New England Journal Of Medicine 2010, 362: 1173-1180. PMID: 20357280, PMCID: PMC2877372, DOI: 10.1056/nejmoa0909087.Peer-Reviewed Original ResearchConceptsCourse of disabilityDisability trajectoriesOrgan failureAdvanced dementiaSudden deathOlder personsSevere disabilityCommunity-dwelling older personsTrajectories of disabilityLevel of disabilityCatastrophic disabilityEnd of lifeProgressive disabilityFunctional statusDeath certificatesCommon conditionBaseline assessmentPredominant trajectoriesMonthly interviewsDeathDisabilityLongitudinal studyDementiaFrailtyDecedents
2006
Triggered sampling could help improve longitudinal studies of persons with elevated mortality risk
Dubin JA, Han L, Fried TR. Triggered sampling could help improve longitudinal studies of persons with elevated mortality risk. Journal Of Clinical Epidemiology 2006, 60: 288-293. PMID: 17292023, DOI: 10.1016/j.jclinepi.2006.06.012.Peer-Reviewed Original ResearchConceptsElevated mortality riskMortality riskChronic obstructive pulmonary diseaseLongitudinal studyCongestive heart failureObstructive pulmonary diseaseMixed effects modelsLongitudinal observational studyLongitudinal clinical studyStudy design featuresEffects modelHeart failurePulmonary diseaseAdvanced illnessTreatment preferencesClinical studiesObservational studyFirst triggerStudy designPatientsRiskValuable additionMean preferenceSimilar resultsIllness