2014
Developmental Expression Patterns of GABAA Receptor Subunits in Layer 3 and 5 Pyramidal Cells of Monkey Prefrontal Cortex
Datta D, Arion D, Lewis D. Developmental Expression Patterns of GABAA Receptor Subunits in Layer 3 and 5 Pyramidal Cells of Monkey Prefrontal Cortex. Cerebral Cortex 2014, 25: 2295-2305. PMID: 24610118, PMCID: PMC4494034, DOI: 10.1093/cercor/bhu040.Peer-Reviewed Original ResearchMeSH KeywordsAgingAnimalsFemaleLaser Capture MicrodissectionMacaca mulattaMalePrefrontal CortexPyramidal CellsReal-Time Polymerase Chain ReactionReceptors, AMPAReceptors, GABA-AReceptors, N-Methyl-D-AspartateRNA, MessengerConceptsGABAA receptor subunitsPyramidal cellsMonkey prefrontal cortexReceptor subunitsSubunit expressionLayer 3 pyramidal cellsGABAA receptor subunit expressionPrefrontal cortexGABAA receptor subunit mRNAsLayer 5 pyramidal cellsReceptor subunit changesPrefrontal pyramidal neuronsReceptor subunit expressionPyramidal neuron activityGlutamate receptor subunitsReceptor subunit mRNAsPyramidal cell firingPostnatal developmental changesPyramidal neuronsGABAA receptorsInhibitory inputsNeuron activityFunctional maturationPostnatal developmentCell firing
2012
Translocator Protein 18 kDa (TSPO) Expression in Multiple Sclerosis Patients
Harberts E, Datta D, Chen S, Wohler J, Oh U, Jacobson S. Translocator Protein 18 kDa (TSPO) Expression in Multiple Sclerosis Patients. Journal Of Neuroimmune Pharmacology 2012, 8: 51-57. PMID: 22956240, PMCID: PMC4765953, DOI: 10.1007/s11481-012-9397-5.Peer-Reviewed Original ResearchMeSH KeywordsAcetamidesAdultBiomarkersBrainCell SeparationFemaleHumansIsoquinolinesLeukocytes, MononuclearLipopolysaccharide ReceptorsMagnetic Resonance ImagingMaleMembrane Potential, MitochondrialMiddle AgedMitochondriaMultiple SclerosisPositron-Emission TomographyProtein BindingPyridinesRadioligand AssayRadiopharmaceuticalsReal-Time Polymerase Chain ReactionReceptors, GABAConceptsPeripheral blood mononuclear cellsMultiple sclerosis patientsExpression of TSPOMagnetic resonance imagingPositron emission tomographyTSPO expressionSclerosis patientsCentral nervous system inflammationHealthy donor cohortNervous system inflammationMarkers of inflammationPotential peripheral biomarkerBlood mononuclear cellsTranslocator protein 18TSPO protein expressionSystem inflammationMS patientsNeuroinflammatory conditionsPeripheral biomarkersMononuclear cellsNeuropathologic conditionsDonor cohortInflammatory diseasesHealthy donorsHealthy individuals