2022
Proteomic differences in hippocampus and cortex of sudden unexplained death in childhood
Leitner DF, William C, Faustin A, Askenazi M, Kanshin E, Snuderl M, McGuone D, Wisniewski T, Ueberheide B, Gould L, Devinsky O. Proteomic differences in hippocampus and cortex of sudden unexplained death in childhood. Acta Neuropathologica 2022, 143: 585-599. PMID: 35333953, PMCID: PMC8953962, DOI: 10.1007/s00401-022-02414-7.Peer-Reviewed Original ResearchConceptsSudden unexplained deathDentate gyrusFrontal cortexClinical historyCA1-3Unexplained deathBrain regionsSudden unexpected deathHippocampal dentate gyrusFebrile seizure historyAcute phase responseCause of deathYears of ageMechanism of deathCircumstances of deathSUDC casesMolecular signaling pathwaysClinical featuresSeizure historyPathological featuresMultiple etiologiesCornu ammonisUnexpected deathPreventive strategiesAncillary testing
2016
Neuroblast Distribution after Cortical Impact Is Influenced by White Matter Injury in the Immature Gyrencephalic Brain
Taylor SR, Smith CM, Keeley KL, McGuone D, Dodge CP, Duhaime AC, Costine BA. Neuroblast Distribution after Cortical Impact Is Influenced by White Matter Injury in the Immature Gyrencephalic Brain. Frontiers In Neuroscience 2016, 10: 387. PMID: 27601978, PMCID: PMC4994423, DOI: 10.3389/fnins.2016.00387.Peer-Reviewed Original ResearchTraumatic brain injuryWhite matter injuryCortical impactSubventricular zoneWhite matterGyrencephalic brainBrain regionsInjury sitePostnatal populationGray matterPostnatal day 7Age-dependent increaseNumber of neuroblastsCortical contusionNeurogenic responseCortical injuryMajor white matterSham surgeryPND 14PND 5Potential complicationsBrain injuryPopulation of neuroblastsDay 7Chronic effects