Publications

2023

Aging gene signature of memory CD8(+) T cells is associated with neurocognitive functioning in Alzheimer's disease.Young JJ, Park HJ, Kim M, Par-Young J, Bartlett H, Kim HS, Unlu S, Osmani L, Shin MS, Bucala R, van Dyck CH, Allore H, Mecca AP, You S, Kang I. Immun Ageing. 2023 Dec 2; 2023 Dec 2. PMID: 38042785.
Gait and/or balance disturbances associated with Alzheimer's dementia among older adults with amnestic mild cognitive impairment: A longitudinal observational study.Ahn S, Chung JW, Crouter SE, Lee JA, Lee CE, Anderson JG. J Adv Nurs. 2023 Dec; 2023 Jun 29. PMID: 37386779.
Heterogeneity of Response to Methylphenidate in Apathetic Patients in the ADMET 2 Trial.Lanctôt KL, Rivet L, Tumati S, Perin J, Sankhe K, Vieira D, Mintzer J, Rosenberg PB, Shade D, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey AI, Padala KP, Herrmann N. Am J Geriatr Psychiatry. 2023 Dec; 2023 Jun 15. PMID: 37385898.
Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease.Archer DB, Eissman JM, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA, Cuccaro ML, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Mayeux RP, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Dumitrescu L, Hohman TJ. Alzheimers Dement. 2023 Nov 20; 2023 Nov 20. PMID: 37985223.
Sex-specific genetic architecture of late-life memory performance.Eissman JM, Archer DB, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Mayeux RP, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Hohman TJ, Dumitrescu L. Alzheimers Dement. 2023 Nov 20; 2023 Nov 20. PMID: 37984853.
Neuronal transcriptome, tau and synapse loss in Alzheimer's knock-in mice require prion protein.Stoner A, Fu L, Nicholson L, Zheng C, Toyonaga T, Spurrier J, Laird W, Cai Z, Strittmatter SM. Alzheimers Res Ther. 2023 Nov 15; 2023 Nov 15. PMID: 37968719.
Quantitative estimate of cognitive resilience and its medical and genetic associations.Phongpreecha T, Godrich D, Berson E, Espinosa C, Kim Y, Cholerton B, Chang AL, Mataraso S, Bukhari SA, Perna A, Yakabi K, Montine KS, Poston KL, Mormino E, White L, Beecham G, Aghaeepour N, Montine TJ. Alzheimers Res Ther. 2023 Nov 6; 2023 Nov 6. PMID: 37926851.
A neurodegeneration checkpoint mediated by REST protects against the onset of Alzheimer's disease.Aron L, Qiu C, Ngian ZK, Liang M, Drake D, Choi J, Fernandez MA, Roche P, Bunting EL, Lacey EK, Hamplova SE, Yuan M, Wolfe MS, Bennett DA, Lee EA, Yankner BA. Nat Commun. 2023 Nov 2; 2023 Nov 2. PMID: 37919281.
Distinct latent symptom profiles in late-onset depressive symptoms in community-dwelling older adults.Taiwo Z, Tighe EL, Tone EB, Light SN, Dotson VM. Aging Ment Health. 2023 Nov-Dec; 2023 May 17. PMID: 37194465.
Locus coeruleus pathology is associated with cerebral microangiopathy at autopsy.Freeze WM, Van Veluw SJ, Jansen WJ, Bennett DA, Jacobs HIL. Alzheimers Dement. 2023 Nov; 2023 Apr 24. PMID: 37095709.
Cost consequence analysis of Apathy in Dementia Methylphenidate Trial 2 (ADMET 2).Lanctôt KL, Chen C, Mah E, Kiss A, Li A, Shade D, Scherer RW, Vieira D, Coulibaly H, Rosenberg PB, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Burke WJ, Mintzer J, Herrmann N. Int Psychogeriatr. 2023 Nov; 2023 Apr 17. PMID: 37066690.
Examining racial disparities in the diagnosis of mild cognitive impairment.Kiselica AM, Johnson E, Lewis KR, Trout K. Appl Neuropsychol Adult. 2023 Nov-Dec; 2021 Sep 23. PMID: 34554020.
The Association between Metformin Use and Risk of Developing Severe Dementia among AD Patients with Type 2 Diabetes.Xue Y, Xie X. Biomedicines. 2023 Oct 30; 2023 Oct 30. PMID: 38001936.
Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer's disease.Iyaswamy A, Thakur A, Guan XJ, Krishnamoorthi S, Fung TY, Lu K, Gaurav I, Yang Z, Su CF, Lau KF, Zhang K, Ng RC, Lian Q, Cheung KH, Ye K, Chen HJ, Li M. Signal Transduct Target Ther. 2023 Oct 23; 2023 Oct 23. PMID: 37867176.
Place of Birth and Cognition among Older Americans: Findings from the Harmonized Cognitive Assessment Protocol.Lin Z, Chen X. medRxiv. 2023 Oct 15; 2023 Oct 15. PMID: 37873447.
Clinical characteristics of pathological confirmed prodromal dementia with Lewy bodies.Ting SKS, Saffari SE, Hameed S, Chiew HJ, Ng KP, Ng AS. J Neurol Sci. 2023 Oct 15; 2023 Sep 21. PMID: 37757638.
Differential diagnosis of neurodegenerative dementias with the explainable MRI based machine learning algorithm MUQUBIA.De Francesco S, Crema C, Archetti D, Muscio C, Reid RI, Nigri A, Bruzzone MG, Tagliavini F, Lodi R, D'Angelo E, Boeve B, Kantarci K, Firbank M, Taylor JP, Tiraboschi P, Redolfi A. Sci Rep. 2023 Oct 13; 2023 Oct 13. PMID: 37833302.
Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects.Lee WP, Wang H, Dombroski B, Cheng PL, Tucci A, Si YQ, Farrell J, Tzeng JY, Leung YY, Malamon J, Wang LS, Vardarajan B, Farrer L, Schellenberg G. Res Sq. 2023 Oct 5; 2023 Oct 5. PMID: 37886469.
Predicting cognitive decline in a low-dimensional representation of brain morphology.Lamontagne-Caron R, Desrosiers P, Potvin O, Doyon N, Duchesne S. Sci Rep. 2023 Oct 5; 2023 Oct 5. PMID: 37798311.
In vivo cortical diffusion imaging relates to Alzheimer's disease neuropathology.Torso M, Ridgway GR, Valotti M, Hardingham I, Chance SA. Alzheimers Res Ther. 2023 Oct 4; 2023 Oct 4. PMID: 37794477.
Deep grading for MRI-based differential diagnosis of Alzheimer's disease and Frontotemporal dementia.Nguyen HD, Clément M, Planche V, Mansencal B, Coupé P. Artif Intell Med. 2023 Oct; 2023 Aug 18. PMID: 37783553.
Early-onset Alzheimer's disease explained by polygenic risk of late-onset disease?Mantyh WG, Cochran JN, Taylor JW, Broce IJ, Geier EG, Bonham LW, Anderson AG, Sirkis DW, Joie R, Iaccarino L, Chaudhary K, Edwards L, Strom A, Grant H, Allen IE, Miller ZA, Gorno-Tempini ML, Kramer JH, Miller BL, Desikan RS, Rabinovici GD, Yokoyama JS. Alzheimers Dement (Amst). 2023 Oct-Dec; 2023 Sep 28. PMID: 37780862.
Sex differences in associations between APOE ε2 and longitudinal cognitive decline.Wood ME, Xiong LY, Wong YY, Buckley RF, Swardfager W, Masellis M, Lim ASP, Nichols E, Joie R, Casaletto KB, Kumar RG, Dams-O'Connor K, Palta P, George KM, Satizabal CL, Barnes LL, Schneider JA, Binet AP, Villeneuve S, Pa J, Brickman AM, Black SE, Rabin JS. Alzheimers Dement. 2023 Oct; 2023 Mar 30. PMID: 36994910.
Characterizing mild cognitive impairment to predict incident dementia in adults with bipolar disorder: What should the benchmark be?Andruchow D, Cunningham D, Sharma MJ, Ismail Z, Callahan BL. Clin Neuropsychol. 2023 Oct; 2022 Oct 29. PMID: 36308307.
Trial of Solanezumab in Preclinical Alzheimer's Disease.Sperling RA, Donohue MC, Raman R, Rafii MS, Johnson K, Masters CL, van Dyck CH, Iwatsubo T, Marshall GA, Yaari R, Mancini M, Holdridge KC, Case M, Sims JR, Aisen PS. N Engl J Med. 2023 Sep 21; 2023 Jul 17. PMID: 37458272.
Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism.Takahashi H, Perez-Canamas A, Ye H, Han X, Strittmatter SM. bioRxiv. 2023 Sep 14; 2023 Sep 14. PMID: 37745346.
Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects.Wang H, Dombroski BA, Cheng PL, Tucci A, Si YQ, Farrell JJ, Tzeng JY, Leung YY, Malamon JS, Wang LS, Vardarajan BN, Farrer LA, Schellenberg GD, Lee WP. medRxiv. 2023 Sep 13; 2023 Sep 13. PMID: 37745545.
Lower mortality risk in APOE4 carriers with normal cognitive ageing.Pirraglia E, Glodzik L, Shao Y. Sci Rep. 2023 Sep 12; 2023 Sep 12. PMID: 37699966.
Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.Walters S, Contreras AG, Eissman JM, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Peterson A, Gifford KA, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Hohman TJ, Dumitrescu L. JAMA Neurol. 2023 Sep 1. PMID: 37459083.
APOE genotypes modify the obesity paradox in dementia.Shinohara M, Gheni G, Hitomi J, Bu G, Sato N. J Neurol Neurosurg Psychiatry. 2023 Sep; 2023 Jul 6. PMID: 37414536.
Demographically-adjusted normative data among Latinos for the version 3 of the Alzheimer's Disease Centers' Neuropsychological Test Battery in the Uniform Data Set.Marquine MJ, Parks A, Perales-Puchalt J, González DA, Rosado-Bruno M, North R, Pieper C, Werry AE, Kiselica A, Chapman S, Dodge H, Gauthreaux K, Kukull WA, Rascovsky K. Alzheimers Dement. 2023 Sep; 2023 Jun 25. PMID: 37356069.
Is the association between cognitive disease progression and atrial fibrillation modified by sex?Wood KA, Han F, Ko YA, Wharton WW. Alzheimers Dement. 2023 Sep; 2023 Jun 23. PMID: 37350284.
Comorbidities in Early-Onset Sporadic versus Presenilin-1 Mutation-Associated Alzheimer's Disease Dementia: Evidence for Dependency on Alzheimer's Disease Neuropathological Changes.Sepulveda-Falla D, Lanau CAV, White C 3rd, Serrano GE, Acosta-Uribe J, Mejía-Cupajita B, Villalba-Moreno ND, Lu P, Glatzel M, Kofler JK, Ghetti B, Frosch MP, Restrepo FL, Kosik KS, Beach TG. medRxiv. 2023 Aug 16; 2023 Aug 16. PMID: 37646002.
Associations between dementia staging, neuropsychiatric behavioral symptoms, and divorce or separation in late life: A case control study.Monin JK, McAvay G, Zang E, Vander Wyk B, Carrión CI, Allore H. PLoS One. 2023; 2023 Aug 16. PMID: 37585365.
Disease severity and mortality in Alzheimer's disease: an analysis using the U.S. National Alzheimer's Coordinating Center Uniform Data Set.Crowell V, Reyes A, Zhou SQ, Vassilaki M, Gsteiger S, Gustavsson A. BMC Neurol. 2023 Aug 14; 2023 Aug 14. PMID: 37580727.
Assessment of Gray Matter Microstructure and Synaptic Density in Alzheimer's Disease: A Multimodal Imaging Study With DTI and SV2A PET.Silva-Rudberg JA, Salardini E, O'Dell RS, Chen MK, Ra J, Georgelos JK, Morehouse MR, Melino KP, Varma P, Toyonaga T, Nabulsi NB, Huang Y, Carson RE, van Dyck CH, Mecca AP. Am J Geriatr Psychiatry. 2023 Aug 11; 2023 Aug 11. PMID: 37673749.
Network analysis of neuropsychiatric symptoms in Alzheimer's disease.Goodwin GJ, Moeller S, Nguyen A, Cummings JL, John SE. Alzheimers Res Ther. 2023 Aug 11; 2023 Aug 11. PMID: 37568209.
Racial and ethnic differences in neuropsychiatric symptoms and progression to incident cognitive impairment among community-dwelling participants.Babulal GM, Zhu Y, Trani JF. Alzheimers Dement. 2023 Aug; 2023 Feb 25. PMID: 36840665.
Utility of empathy informant report in FTD differential diagnosis.Lane CM, Lee M, Lowe J, Bolton C, Pyykkonen BA. J Int Neuropsychol Soc. 2023 Aug; 2022 Sep 26. PMID: 36154934.
Splenium tract projections of the corpus callosum to the parietal cortex classifies Alzheimer's disease and mild cognitive impairment.Delvenne JF, Scally B, Rose Burke M. Neurosci Lett. 2023 Jul 27; 2023 Jun 9. PMID: 37302566.
XGBoost-SHAP-based interpretable diagnostic framework for alzheimer's disease.Yi F, Yang H, Chen D, Qin Y, Han H, Cui J, Bai W, Ma Y, Zhang R, Yu H. BMC Med Inform Decis Mak. 2023 Jul 25; 2023 Jul 25. PMID: 37491248.
Weight Change and Neuropsychiatric Symptoms in Alzheimer's Disease and Frontotemporal Dementia: Associations with Cognitive Decline.Morrow CB, Leoutsakos J, Yan H, Onyike C, Kamath V. J Alzheimers Dis Rep. 2023; 2023 Jul 24. PMID: 37662607.
APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology.Chemparathy A, Guen YL, Chen S, Lee EG, Leong L, Gorzynski J, Xu G, Belloy M, Kasireddy N, Tauber AP, Williams K, Stewart I, Wingo T, Lah J, Jayadev S, Hales C, Peskind E, Child DD, Keene CD, Cong L, Ashley E, Yu CE, Greicius MD. medRxiv. 2023 Jul 24; 2023 Jul 24. PMID: 37547016.
Exploring the Potential of Aptamers in Targeting Neuroinflammation and Neurodegenerative Disorders: Opportunities and Challenges.Kong AH, Wu AJ, Ho OK, Leung MM, Huang AS, Yu Y, Zhang G, Lyu A, Li M, Cheung KH. Int J Mol Sci. 2023 Jul 22; 2023 Jul 22. PMID: 37511539.
Identifying healthy individuals with Alzheimer's disease neuroimaging phenotypes in the UK Biobank.Azevedo T, Bethlehem RAI, Whiteside DJ, Swaddiwudhipong N, Rowe JB, Lió P, Rittman T. Commun Med (Lond). 2023 Jul 20; 2023 Jul 20. PMID: 37474615.
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. medRxiv. 2023 Jul 8; 2023 Jul 8. PMID: 37461624.
Clonal hematopoiesis is associated with protection from Alzheimer's disease.Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D, Yao W, Beiser A, Bick AG, Bis JC, Fornage M, Longstreth WT Jr, Lopez OL, Natarajan P, Psaty BM, Satizabal CL, Weinstock J, Larson EB, Crane PK, Keene CD, Seshadri S, Satpathy AT, Montine TJ, Jaiswal S. Nat Med. 2023 Jul; 2023 Jun 15. PMID: 37322115.
Longitudinal head-to-head comparison of (11)C-PiB and (18)F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease.Chen CD, McCullough A, Gordon B, Joseph-Mathurin N, Flores S, McKay NS, Hobbs DA, Hornbeck R, Fagan AM, Cruchaga C, Goate AM, Perrin RJ, Wang G, Li Y, Shi X, Xiong C, Pontecorvo MJ, Klein G, Su Y, Klunk WE, Jack C, Koeppe R, Snider BJ, Berman SB, Roberson ED, Brosch J, Surti G, Jiménez-Velázquez IZ, Galasko D, Honig LS, Brooks WS, Clarnette R, Wallon D, Dubois B, Pariente J, Pasquier F, Sanchez-Valle R, Shcherbinin S, Higgins I, Tunali I, Masters CL, van Dyck CH, Masellis M, Hsiung R, Gauthier S, Salloway S, Clifford DB, Mills S, Supnet-Bell C, McDade E, Bateman RJ, Benzinger TLS. Eur J Nucl Med Mol Imaging. 2023 Jul; 2023 Apr 5. PMID: 37017737.
Effects of race, baseline cognition, and APOE on the association of affective dysregulation with incident dementia: A longitudinal study of dementia-free older adults.Ebrahim IM, Ghahremani M, Camicioli R, Smith EE, Ismail Z. J Affect Disord. 2023 Jul 1; 2023 Mar 28. PMID: 36997127.
Prediction of neuropathologic lesions from clinical data.Phongpreecha T, Cholerton B, Bukhari S, Chang AL, De Francesco D, Thuraiappah M, Godrich D, Perna A, Becker MG, Ravindra NG, Espinosa C, Kim Y, Berson E, Mataraso S, Sha SJ, Fox EJ, Montine KS, Baker LD, Craft S, White L, Poston KL, Beecham G, Aghaeepour N, Montine TJ. Alzheimers Dement. 2023 Jul; 2023 Jan 21. PMID: 36681388.
Initial non-amnestic symptoms relate to faster rate of functional and cognitive decline compared to amnestic symptoms in neuropathologically confirmed dementias.Pillai JA, Bena J, Maly EF, Leverenz JB. Alzheimers Dement. 2023 Jul; 2023 Jan 17. PMID: 36648159.
PPAD: a deep learning architecture to predict progression of Alzheimer's disease.Al Olaimat M, Martinez J, Saeed F, Bozdag S. Bioinformatics. 2023 Jun 30. PMID: 37387135.
Mass Spectrometry in Cerebrospinal Fluid Uncovers Association of Glycolysis Biomarkers with Alzheimer's Disease in a Large Clinical Sample.de Geus MB, Leslie SN, Lam T, Wang W, Kivisakk P, Nairn AC, Arnold SE, Carlyle BC. Res Sq. 2023 Jun 27; 2023 Jun 27. PMID: 37461556.
Exposure to ultrafine particles and cognitive decline among older people in the United States.Gan W, Manning KJ, Cleary EG, Fortinsky RH, Brugge D. Environ Res. 2023 Jun 15; 2023 Mar 24. PMID: 36965813.
Scientific Rationale for the Treatment of Cognitive Deficits from Long COVID.Fesharaki Zadeh A, Arnsten AFT, Wang M. Neurol Int. 2023 May 31; 2023 May 31. PMID: 37368329.
Cognitive and Clinical Characteristics of Patients With Limbic-Predominant Age-Related TDP-43 Encephalopathy.Butler Pagnotti RM, Pudumjee SB, Cross CL, Miller JB. Neurology. 2023 May 9; 2023 Mar 20. PMID: 36941071.
MRI-based basal forebrain atrophy and volumetric signatures associated with limbic TDP-43 compared to Alzheimer's disease pathology.Teipel S, Grothe MJ. Neurobiol Dis. 2023 May; 2023 Mar 8. PMID: 36898615.
Development and validation of a 13-gene signature associated with immune function for the detection of Alzheimer's disease.Zhu M, Hou T, Jia L, Tan Q, Qiu C, Du Y. Neurobiol Aging. 2023 May; 2022 Dec 31. PMID: 36842362.
APOE ε4 is associated with earlier symptom onset in LOAD but later symptom onset in EOAD.Polsinelli AJ, Lane KA, Manchella MK, Logan PE, Gao S, Apostolova LG. Alzheimers Dement. 2023 May; 2023 Feb 1. PMID: 36722399.
Associations of WWC1 variants with Alzheimer's disease and vascular dementia among rural older adults in China: A population-based study.Wang C, Han X, Dong Y, Liu C, Wang X, Hou T, Tan Q, Wang Y, Du Y, Qiu C. Neurobiol Aging. 2023 May; 2023 Jan 8. PMID: 36669907.
Natural cubic splines for the analysis of Alzheimer's clinical trials.Donohue MC, Langford O, Insel PS, van Dyck CH, Petersen RC, Craft S, Sethuraman G, Raman R, Aisen PS. Pharm Stat. 2023 May-Jun; 2023 Jan 10. PMID: 36627206.
APOE ε4 carrier status and sex differentiate rates of cognitive decline in early- and late-onset Alzheimer's disease.Polsinelli AJ, Logan PE, Lane KA, Manchella MK, Nemes S, Sanjay AB, Gao S, Apostolova LG. Alzheimers Dement. 2023 May; 2022 Nov 17. PMID: 36394443.
Network Analysis of Neuropsychiatric Symptoms in Alzheimer's Disease.Goodwin GJ, Moeller S, Nguyen A, Cummings JL, John SE. Res Sq. 2023 Apr 28; 2023 Apr 28. PMID: 37163090.
Lecanemab in Early Alzheimer's Disease. Reply.van Dyck CH, Sabbagh M, Cohen S. N Engl J Med. 2023 Apr 27. PMID: 37099355.
Association of vascular and degenerative brain pathologies and past medical history from the National Alzheimer's Coordinating Center Database.Scambray KA, Nguyen HL, Sajjadi SA. J Neuropathol Exp Neurol. 2023 Apr 20. PMID: 36947583.
Interaction between KLOTHO-VS Heterozygosity and APOE ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer's Disease.Chen XR, Shao Y, Sadowski MJ, On Behalf Of The Alzheimer's Disease Neuroimaging Initiative. Genes (Basel). 2023 Apr 15; 2023 Apr 15. PMID: 37107675.
Ecological validity of cognitive fluctuations in dementia with Lewy bodies.Webber TA, Lorkiewicz SA, Kiselica AM, Woods SP. J Int Neuropsychol Soc. 2023 Apr 14; 2023 Apr 14. PMID: 37057867.
Brain connectomics: time for a molecular imaging perspective?Sala A, Lizarraga A, Caminiti SP, Calhoun VD, Eickhoff SB, Habeck C, Jamadar SD, Perani D, Pereira JB, Veronese M, Yakushev I. Trends Cogn Sci. 2023 Apr; 2023 Jan 6. PMID: 36621368.
Associations between neuropsychiatric symptoms and incident Alzheimer's dementia in men versus women.Liampas I, Siokas V, Lyketsos CG, Dardiotis E. J Neurol. 2023 Apr; 2022 Dec 26. PMID: 36572715.
A flexible modeling approach for biomarker-based computation of absolute risk of Alzheimer's disease dementia.Hartz SM, Mozersky J, Schindler SE, Linnenbringer E, Wang J, Gordon BA, Raji CA, Moulder KL, West T, Benzinger TLS, Cruchaga C, Hassenstab JJ, Bierut LJ, Xiong C, Morris JC. Alzheimers Dement. 2023 Apr; 2022 Sep 30. PMID: 36178120.
Classification statistics of the Montreal Cognitive Assessment (MoCA): Are we interpreting the MoCA correctly?Ratcliffe LN, McDonald T, Robinson B, Sass JR, Loring DW, Hewitt KC. Clin Neuropsychol. 2023 Apr; 2022 Jun 14. PMID: 35699222.
Cognitive differences across ethnoracial category, socioeconomic status across the Alzheimer's disease spectrum: Can an ability discrepancy score level the playing field?McDonough IM, Cody SL, Harrell ER, Garrett SL, Popp TE. Mem Cognit. 2023 Apr; 2022 Mar 25. PMID: 35338450.
Examining the Validity and Utility of Montreal Cognitive Assessment Domain Scores for Early Neurocognitive Disorders.Ang LC, Yap P, Tay SY, Koay WI, Liew TM. J Am Med Dir Assoc. 2023 Mar; 2023 Feb 6. PMID: 36758620.
Brief Report: An Evaluation of Item Bias on the Functional Activities Questionnaire.González DA, Clark MJ, Gonzales MM, Benge J. Arch Clin Neuropsychol. 2023 Feb 18. PMID: 36062452.
Chemical Entity Normalization for Successful Translational Development of Alzheimer's Disease and Dementia Therapeutics.Mullin S, McDougal R, Cheung KH, Kilicoglu H, Beck A, Zeiss CJ. Res Sq. 2023 Feb 16; 2023 Feb 16. PMID: 36824778.
Aging of the brain in bipolar disorder: Illness- and onset-related effects in cortical thickness and subcortical gray matter volume.Villa LM, Colic L, Kim JA, Sankar A, Goldman DA, Lessing B, Pittman B, Alexopoulos GS, van Dyck CH, Blumberg HP. J Affect Disord. 2023 Feb 15; 2022 Dec 13. PMID: 36526112.
Response to: Multiple Cerebral Hemorrhages in a Patient Receiving Lecanemab and Treated with t-PA for Stroke.Sabbagh M, van Dyck CH. N Engl J Med. 2023 Feb 2; 2023 Jan 4. PMID: 36599073.
Anosmia, mild cognitive impairment, and biomarkers of brain aging in older adults.Dong Y, Li Y, Liu K, Han X, Liu R, Ren Y, Cong L, Zhang Q, Hou T, Song L, Tang S, Shi L, Luo Y, Kalpouzos G, Laukka EJ, Winblad B, Wang Y, Du Y, Qiu C. Alzheimers Dement. 2023 Feb; 2022 Sep 15. PMID: 36341691.
PPAD: A deep learning architecture to predict progression of Alzheimer's disease.Al Olaimat M, Martinez J, Saeed F, Bozdag S. bioRxiv. 2023 Jan 31; 2023 Jan 31. PMID: 36778453.
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.de Arce KP, Ribic A, Chowdhury D, Watters K, Thompson GJ, Sanganahalli BG, Lippard ETC, Rohlmann A, Strittmatter SM, Missler M, Hyder F, Biederer T. Nat Commun. 2023 Jan 28; 2023 Jan 28. PMID: 36709330.
Cognitive resistance to and resilience against multiple comorbid neurodegenerative pathologies and the impact of APOE status.Walker JM, Richardson TE. J Neuropathol Exp Neurol. 2023 Jan 20. PMID: 36458951.
Estimating Bidirectional Transitions and Identifying Predictors of Mild Cognitive Impairment.Qin Y, Han H, Li Y, Cui J, Jia H, Ge X, Ma Y, Bai W, Zhang R, Chen D, Yi F, Yu H. Neurology. 2023 Jan 17; 2022 Oct 11. PMID: 36220593.
Intracranial artery stenosis is associated with cortical thinning in stroke-free individuals of two longitudinal cohorts.Yang D, Masurkar AV, Khasiyev F, Rundek T, Wright CB, Elkind MSV, Sacco RL, Gutierrez J. J Neurol Sci. 2023 Jan 15; 2022 Dec 23. PMID: 36577280.
Intra-individual variability in cognitive performance predicts functional decline in Parkinson's disease.Davis JJ, Sivaramakrishnan A, Rolin S, Subramanian S. Appl Neuropsychol Adult. 2023 Jan 10; 2023 Jan 10. PMID: 36628434.
Lecanemab in Early Alzheimer's Disease.van Dyck CH, Swanson CJ, Aisen P, Bateman RJ, Chen C, Gee M, Kanekiyo M, Li D, Reyderman L, Cohen S, Froelich L, Katayama S, Sabbagh M, Vellas B, Watson D, Dhadda S, Irizarry M, Kramer LD, Iwatsubo T. N Engl J Med. 2023 Jan 5; 2022 Nov 29. PMID: 36449413.
Cardiovascular Risk Factors and Risk of Alzheimer Disease and Mortality: A Latent Class Approach.Ruthirakuhan M, Cogo-Moreira H, Swardfager W, Herrmann N, Lanctot KL, Black SE. J Am Heart Assoc. 2023 Jan 3; 2022 Dec 24. PMID: 36565204.
Genetic underpinnings of brain structural connectome for young adults.Zhao Y, Chang C, Zhang J, Zhang Z. J Am Stat Assoc. 2023; 2023 Feb 6. PMID: 37982009.
Plasma Amyloid-β, Total Tau, and Neurofilament Light Chain Across the Alzheimer's Disease Clinical Spectrum: A Population-Based Study.Dong Y, Hou T, Li Y, Liu R, Cong L, Liu K, Liu C, Han X, Ren Y, Tang S, Winblad B, Blennow K, Wang Y, Du Y, Qiu C. J Alzheimers Dis. 2023. PMID: 37899059.
Lecanemab Clarity AD: Quality-of-Life Results from a Randomized, Double-Blind Phase 3 Trial in Early Alzheimer's Disease.Cohen S, van Dyck CH, Gee M, Doherty T, Kanekiyo M, Dhadda S, Li D, Hersch S, Irizarry M, Kramer LD. J Prev Alzheimers Dis. 2023. PMID: 37874099.
Predicting Progression to Clinical Alzheimer's Disease Dementia Using the Random Survival Forest.Song S, Asken B, Armstrong MJ, Yang Y, Li Z. J Alzheimers Dis. 2023. PMID: 37545237.
Association of Lifelong Cognitive Reserve with Dementia and Mild Cognitive Impairment among Older Adults with Limited Formal Education: A Population-Based Cohort Study.Li Y, Ren Y, Cong L, Hou T, Song L, Wang M, Wang X, Han X, Tang S, Zhang Q, Dekhtyar S, Wang Y, Du Y, Qiu C. Dement Geriatr Cogn Disord. 2023; 2023 Jul 29. PMID: 37517389.
Ventricular Electrocardiographic Signatures Associated with Dementia and Plasma Alzheimer's Disease Biomarkers in Older Adults: A Population-Based Study.Mao M, Wang C, Hou T, Han X, Liu R, Han Q, Dong Y, Wang J, Liu C, Cong L, Imahori Y, Vetrano DL, Wang Y, Du Y, Qiu C. J Alzheimers Dis. 2023. PMID: 37424464.
Principal component analysis of synaptic density measured with [(11)C]UCB-J PET in early Alzheimer's disease.O'Dell RS, Higgins-Chen A, Gupta D, Chen MK, Naganawa M, Toyonaga T, Lu Y, Ni G, Chupak A, Zhao W, Salardini E, Nabulsi NB, Huang Y, Arnsten AFT, Carson RE, van Dyck CH, Mecca AP. Neuroimage Clin. 2023; 2023 Jun 22. PMID: 37422964.
Validation of the CogDrisk Instrument as Predictive of Dementia in Four General Community-Dwelling Populations.Kootar S, Huque MH, Eramudugolla R, Rizzuto D, Carlson MC, Odden MC, Lopez OL, Qiu C, Fratiglioni L, Han SD, Bennett DA, Peters R, Anstey KJ. J Prev Alzheimers Dis. 2023. PMID: 37357288.
Imaging features of small vessel disease in cerebral amyloid angiopathy among patients with Alzheimer's disease.Nagaraja N, DeKosky S, Duara R, Kong L, Wang WE, Vaillancourt D, Albayram M. Neuroimage Clin. 2023; 2023 May 17. PMID: 37245492.
Retention of Study Partners in Longitudinal Studies of Alzheimer Disease.Bollinger RM, Gabel M, Coble DW, Chen SW, Keleman AA, Doralus J, Chin E, Lingler JH, Grill JD, Stark SL, Edwards DF. J Alzheimers Dis. 2023. PMID: 37212114.
Prevalence and Progression of Subjective Cognitive Decline Among Rural Chinese Older Adults: A Population-Based Study.Xu S, Ren Y, Liu R, Li Y, Hou T, Wang Y, Wang X, Wang L, Monastero R, Du Y, Cong L, Qiu C. J Alzheimers Dis. 2023. PMID: 37182880.
Associations of Microvascular Dysfunction with Mild Cognitive Impairment and Cognitive Function Among Rural-Dwelling Older Adults in China.Jiang C, Wang Y, Dong Y, Liu R, Song L, Wang S, Xu Z, Niu S, Ren Y, Han X, Zhao M, Wang J, Li X, Cong L, Hou T, Zhang Q, Du Y, Qiu C. J Alzheimers Dis. 2023. PMID: 37182877.
Mediation of Reduced Hippocampal Volume by Cerebral Amyloid Angiopathy in Pathologically Confirmed Patients with Alzheimer's Disease.Nagaraja N, Wang WE, Duara R, DeKosky ST, Vaillancourt D. J Alzheimers Dis. 2023. PMID: 37038809.
Sleep Disturbances Predict Cognitive Decline in Cognitively Healthy Adults.Zawar I, Mattos MK, Manning C, Patrie J, Quigg M. J Alzheimers Dis. 2023. PMID: 36970907.
Predicting Progression from Normal to MCI and from MCI to AD Using Clinical Variables in the National Alzheimer's Coordinating Center Uniform Data Set Version 3: Application of Machine Learning Models and a Probability Calculator.Pang Y, Kukull W, Sano M, Albin RL, Shen C, Zhou J, Dodge HH. J Prev Alzheimers Dis. 2023. PMID: 36946457.
Utility of Environmental Complexity as a Predictor of Alzheimer's Disease Diagnosis: A Big-Data Machine Learning Approach.Yuan M, Kennedy KM. J Prev Alzheimers Dis. 2023. PMID: 36946449.
Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab.Mallinckrodt C, Tian Y, Aisen PS, Barkhof F, Cohen S, Dent G, Hansson O, Harrison K, Iwatsubo T, Mummery CJ, Muralidharan KK, Nestorov I, Nisenbaum L, Rajagovindan R, von Hehn C, van Dyck CH, Vellas B, Wu S, Zhu Y, Sandrock A, Chen T, Budd Haeberlein S. J Prev Alzheimers Dis. 2023. PMID: 36946443.
Cognitive and Neuropsychological Profiles in Alzheimer's Disease and Primary Age-Related Tauopathy and the Influence of Comorbid Neuropathologies.Walker JM, Gonzales MM, Goette W, Farrell K, White Iii CL, Crary JF, Richardson TE. J Alzheimers Dis. 2023. PMID: 36847012.
Cognitive Aging with Dementia, Mild Cognitive Impairment, or No Impairment: A Comparison of Same- and Mixed-Sex Couples.Correro Ii AN, Gauthreaux K, Perales-Puchalt J, Chen YC, Chan KCG, Kukull WA, Flatt JD. J Alzheimers Dis. 2023. PMID: 36710669.
TDP-43 Pathology in the Setting of Intermediate and High Alzheimer's Disease Neuropathologic Changes: A Preliminary Evaluation Across Ethnoracial Groups.Huie EZ, Escudero A, Saito N, Harvey D, Nguyen ML, Lucot KL, LaGrande J, Mungas D, DeCarli C, Lamar M, Schneider JA, Kapasi A, Rissman RA, Teich AF, Dugger BN. J Alzheimers Dis. 2023. PMID: 36617779.
Novel Genetic Variants in TP37, PIK3R1, CALM1, and PLCG2 of the Neurotrophin Signaling Pathway Are Associated with the Progression from Mild Cognitive Impairment to Alzheimer's Disease.Li H, Liu H, Lutz MW, Luo S. J Alzheimers Dis. 2023. PMID: 36530083.
The Spectrum of Alzheimer-Type Pathology in Cognitively Normal Individuals.Walker JM, Dehkordi SK, Schaffert J, Goette W, White Iii CL, Richardson TE, Zare H. J Alzheimers Dis. 2023. PMID: 36502330.
Exosomal miR-532-5p induced by long-term exercise rescues blood-brain barrier function in 5XFAD mice via downregulation of EPHA4.Liang X, Fa W, Wang N, Peng Y, Liu C, Zhu M, Tian N, Wang Y, Han X, Qiu C, Hou T, Du Y. Aging Cell. 2023 Jan; 2022 Dec 9. PMID: 36494892.
Persistent depressive symptoms are associated with frontal regional atrophy in patients with Alzheimer's disease.Sinclair LI, Ballard CG. Int J Geriatr Psychiatry. 2023 Jan. PMID: 36482861.
Psychometric Evaluation of the Perceived Research Burden Assessment (PeRBA) in Longitudinal Studies of Alzheimer Disease Using Rasch Analysis.Keleman AA, Chang CH, Bollinger RM, Lingler JH, Gabel M, Stark SL. Alzheimer Dis Assoc Disord. 2023 Jan-Mar 01; 2022 Oct 14. PMID: 36251929.
Longitudinal Predictors of Informant-Rated Everyday Function in Mild Cognitive Impairment.Divers RM, De Vito AN, Pugh EA, Robinson A, Weitzner DS, Calamia MR. J Geriatr Psychiatry Neurol. 2023 Jan; 2022 Apr 19. PMID: 35439098.

2022

Review and evaluation of imputation methods for multivariate longitudinal data with mixed-type incomplete variables.Cao Y, Allore H, Vander Wyk B, Gutman R. Stat Med. 2022 Dec 30; 2022 Oct 11. PMID: 36220138.
Examining the Effects of Formal Education Level on the Montreal Cognitive Assessment.White RS, Barber JM, Harp JP, Jicha GA. J Am Board Fam Med. 2022 Dec 23. PMID: 36564192.
PLD3 affects axonal spheroids and network defects in Alzheimer's disease.Yuan P, Zhang M, Tong L, Morse TM, McDougal RA, Ding H, Chan D, Cai Y, Grutzendler J. Nature. 2022 Dec; 2022 Nov 30. PMID: 36450991.
Correlations between sleep disturbance and brain structures associated with neurodegeneration in the National Alzheimer's Coordinating Center Uniform Data Set.Burke S, Grudzien A, Li T, Abril M, Spadola C, Barnes C, Hanson K, Grandner M, DeKosky S. J Clin Neurosci. 2022 Dec; 2022 Aug 13. PMID: 35970678.
Graphical methods for understanding changes in states: Understanding medication use pathways.Wise EA, Adams RJ, Lyketsos CG, Leoutsakos JM. Int J Methods Psychiatr Res. 2022 Dec; 2022 Jul 27. PMID: 35894783.
Subjective cognitive decline, APOE e4 allele, and the risk of neurocognitive disorders: Age- and sex-stratified cohort study.Liew TM. Aust N Z J Psychiatry. 2022 Dec; 2022 Mar 1. PMID: 35229693.
The complex relationship between depression and progression to incident cognitive impairment across race and ethnicity.Babulal GM, Zhu Y, Roe CM, Hudson DL, Williams MM, Murphy SA, Doherty J, Johnson AM, Trani JF. Alzheimers Dement. 2022 Dec; 2022 Feb 25. PMID: 35213795.
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11) C]UCB-J.Mecca AP, O'Dell RS, Sharp ES, Banks ER, Bartlett HH, Zhao W, Lipior S, Diepenbrock NG, Chen MK, Naganawa M, Toyonaga T, Nabulsi NB, Vander Wyk BC, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Alzheimers Dement. 2022 Dec; 2022 Feb 17. PMID: 35174954.
Alcohol use and cognitive performance: a comparison between Greece and the United States.Funk-White M, Moore AA, McEvoy LK, Bondi MW, Bergstrom J, Kaufmann CN. Aging Ment Health. 2022 Dec; 2021 Nov 28. PMID: 34842012.
Multidimensional trajectories of multimorbidity, functional status, cognitive performance, and depressive symptoms among diverse groups of older adults.Quiñones AR, Nagel CL, Botoseneanu A, Newsom JT, Dorr DA, Kaye J, Thielke SM, Allore HG. J Multimorb Comorb. 2022 Jan-Dec; 2022 Nov 30. PMID: 36479143.
The Contribution of Chronic Conditions to Hospitalization, Skilled Nursing Facility Admission, and Death: Variation by Race.Quiñones AR, McAvay GJ, Peak KD, Vander Wyk B, Allore HG. Am J Epidemiol. 2022 Nov 19. PMID: 35932162.
Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease.Gauthreaux K, Mock C, Teylan MA, Culhane JE, Chen YC, Chan KCG, Katsumata Y, Nelson PT, Kukull WA. J Neuropathol Exp Neurol. 2022 Nov 16. PMID: 36264254.
Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer's disease.Wilson EN, Young CB, Ramos Benitez J, Swarovski MS, Feinstein I, Vandijck M, Le Guen Y, Kasireddy NM, Shahid M, Corso NK, Wang Q, Kennedy G, Trelle AN, Lind B, Channappa D, Belnap M, Ramirez V, Skylar-Scott I, Younes K, Yutsis MV, Le Bastard N, Quinn JF, van Dyck CH, Nairn A, Fredericks CA, Tian L, Kerchner GA, Montine TJ, Sha SJ, Davidzon G, Henderson VW, Longo FM, Greicius MD, Wagner AD, Wyss-Coray T, Poston KL, Mormino EC, Andreasson KI. Alzheimers Res Ther. 2022 Nov 12; 2022 Nov 12. PMID: 36371232.
Geographic Variation in Inpatient Care Utilization, Outcomes and Costs for Dementia Patients Aged 65 Years or Older - China, 2017-2019.Lin Z, Ba F, Allore H, Liu GG, Chen X. China CDC Wkly. 2022 Nov 11. PMID: 36483008.
Dementia risk prediction in individuals with mild cognitive impairment: a comparison of Cox regression and machine learning models.Wang M, Greenberg M, Forkert ND, Chekouo T, Afriyie G, Ismail Z, Smith EE, Sajobi TT. BMC Med Res Methodol. 2022 Nov 2; 2022 Nov 2. PMID: 36324086.
Deciphering Spatial Protein-Protein Interactions in Brain Using Proximity Labeling.Mathew B, Bathla S, Williams KR, Nairn AC. Mol Cell Proteomics. 2022 Nov; 2022 Oct 2. PMID: 36198386.
Associations of sleep timing and time in bed with dementia and cognitive decline among Chinese older adults: A cohort study.Liu R, Ren Y, Hou T, Liang X, Dong Y, Wang Y, Cong L, Wang X, Qin Y, Ren J, Sindi S, Tang S, Du Y, Qiu C. J Am Geriatr Soc. 2022 Nov; 2022 Sep 21. PMID: 36128778.
Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials.Ostrowitzki S, Bittner T, Sink KM, Mackey H, Rabe C, Honig LS, Cassetta E, Woodward M, Boada M, van Dyck CH, Grimmer T, Selkoe DJ, Schneider A, Blondeau K, Hu N, Quartino A, Clayton D, Dolton M, Dang Y, Ostaszewski B, Sanabria-Bohórquez SM, Rabbia M, Toth B, Eichenlaub U, Smith J, Honigberg LA, Doody RS. JAMA Neurol. 2022 Nov 1. PMID: 36121669.
Dispersion-based cognitive intra-individual variability in dementia with Lewy bodies.Webber TA, Kiselica AM, Mikula C, Woods SP. Neuropsychology. 2022 Nov; 2022 Sep 15. PMID: 36107707.
Mild behavioral impairment is associated with progression to Alzheimer's disease: A clinicopathological study.Ruthirakuhan M, Ismail Z, Herrmann N, Gallagher D, Lanctôt KL. Alzheimers Dement. 2022 Nov; 2022 Feb 1. PMID: 35103400.
Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies.Tong BC, Huang AS, Wu AJ, Iyaswamy A, Ho OK, Kong AH, Sreenivasmurthy SG, Zhu Z, Su C, Liu J, Song J, Li M, Cheung KH. J Biomed Sci. 2022 Oct 22; 2022 Oct 22. PMID: 36273169.
Generalizable deep learning model for early Alzheimer's disease detection from structural MRIs.Liu S, Masurkar AV, Rusinek H, Chen J, Zhang B, Zhu W, Fernandez-Granda C, Razavian N. Sci Rep. 2022 Oct 17; 2022 Oct 17. PMID: 36253382.
Perceptions of Research Burden and Retention Among Participants in ADRC Cohorts.Gabel M, Bollinger RM, Knox M, Coble DW, Grill JD, Edwards DF, Stark SL, Lingler JH. Alzheimer Dis Assoc Disord. 2022 Oct-Dec 01; 2022 Jul 6. PMID: 35796752.
Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease.Buckles VD, Xiong C, Bateman RJ, Hassenstab J, Allegri R, Berman SB, Chhatwal JP, Danek A, Fagan AM, Ghetti B, Goate A, Graff-Radford N, Jucker M, Levin J, Marcus DS, Masters CL, McCue L, McDade E, Mori H, Moulder KL, Noble JM, Paumier K, Preische O, Ringman JM, Fox NC, Salloway S, Schofield PR, Martins R, Vöglein J, Morris JC. Alzheimers Dement. 2022 Oct; 2021 Dec 2. PMID: 34854530.
Molecular and cellular evolution of the primate dorsolateral prefrontal cortex.Ma S, Skarica M, Li Q, Xu C, Risgaard RD, Tebbenkamp ATN, Mato-Blanco X, Kovner R, Krsnik Ž, de Martin X, Luria V, Martí-Pérez X, Liang D, Karger A, Schmidt DK, Gomez-Sanchez Z, Qi C, Gobeske KT, Pochareddy S, Debnath A, Hottman CJ, Spurrier J, Teo L, Boghdadi AG, Homman-Ludiye J, Ely JJ, Daadi EW, Mi D, Daadi M, Marín O, Hof PR, Rasin MR, Bourne J, Sherwood CC, Santpere G, Girgenti MJ, Strittmatter SM, Sousa AMM, Sestan N. Science. 2022 Sep 30; 2022 Sep 30. PMID: 36007006.
Genetic Association Between Epigenetic Aging-Acceleration and the Progression of Mild Cognitive Impairment to Alzheimer's Disease.Liu H, Lutz M, Luo S. J Gerontol A Biol Sci Med Sci. 2022 Sep 1. PMID: 35797594.
Divergent magnetic resonance imaging atrophy patterns in Alzheimer's disease and primary age-related tauopathy.Quintas-Neves M, Teylan MA, Morais-Ribeiro R, Almeida F, Mock CN, Kukull WA, Crary JF, Oliveira TG. Neurobiol Aging. 2022 Sep; 2022 May 1. PMID: 35640459.
Nonalcoholic fatty liver disease, serum cytokines, and dementia among rural-dwelling older adults in China: A population-based study.Wang Y, Li Y, Liu K, Han X, Dong Y, Wang X, Wang M, Cong L, Zhang Q, Tang S, Hou T, Liu C, Song L, Han X, Vetrano DL, Du Y, Qiu C. Eur J Neurol. 2022 Sep; 2022 Jun 9. PMID: 35608965.
Assessing the Clinical Meaningfulness of the Alzheimer's Disease Composite Score (ADCOMS) Tool.Tahami Monfared AA, Lenderking WR, Savva Y, Ladd MK, Zhang Q. Neurol Ther. 2022 Sep; 2022 May 5. PMID: 35513767.
Differential Involvement of the Locus Coeruleus in Early- and Late-Onset Alzheimer's Disease: A Potential Mechanism of Clinical Differences?Bolton CJ, Tam JW. J Geriatr Psychiatry Neurol. 2022 Sep; 2021 Sep 9. PMID: 34496652.
Neuropsychological networks in cognitively healthy older adults and dementia patients.Nevado A, Del Rio D, Pacios J, Maestú F. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2022 Sep; 2021 Aug 20. PMID: 34415217.
Catastrophic health expenditure among Chinese adults living alone with cognitive impairment: findings from the CHARLS.Li C, Jin S, Cao X, Han L, Sun N, Allore H, Hoogendijk EO, Xu X, Feng Q, Liu X, Liu Z. BMC Geriatr. 2022 Aug 4; 2022 Aug 4. PMID: 35922775.
An Exploration of Subgroups of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Their Risks of Conversion to Dementia or Death.Qiu J, Goldstein FC, Hanfelt JJ. Am J Geriatr Psychiatry. 2022 Aug; 2022 Jan 3. PMID: 35067420.
Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation.Lennon JC, Aita SL, Bene VAD, Rhoads T, Resch ZJ, Eloi JM, Walker KA. Alzheimers Dement. 2022 Aug; 2021 Dec 2. PMID: 34854531.
The ecological validity of the Uniform Data Set 3.0 neuropsychological battery in individuals with mild cognitive impairment and dementia.Benge JF, Artz JD, Kiselica AM. Clin Neuropsychol. 2022 Aug; 2020 Oct 26. PMID: 33103615.
Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease.Thrush KL, Bennett DA, Gaiteri C, Horvath S, Dyck CHV, Higgins-Chen AT, Levine ME. Aging (Albany NY). 2022 Jul 30; 2022 Jul 30. PMID: 35907208.
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability.Bae T, Fasching L, Wang Y, Shin JH, Suvakov M, Jang Y, Norton S, Dias C, Mariani J, Jourdon A, Wu F, Panda A, Pattni R, Chahine Y, Yeh R, Roberts RC, Huttner A, Kleinman JE, Hyde TM, Straub RE, Walsh CA, Urban AE, Leckman JF, Weinberger DR, Vaccarino FM, Abyzov A. Science. 2022 Jul 29; 2022 Jul 28. PMID: 35901164.
Acetyl-cholinesterase-inhibitors slow cognitive decline and decrease overall mortality in older patients with dementia.Zuin M, Cherubini A, Volpato S, Ferrucci L, Zuliani G. Sci Rep. 2022 Jul 16; 2022 Jul 16. PMID: 35842477.
A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking.Higgins-Chen AT, Thrush KL, Wang Y, Minteer CJ, Kuo PL, Wang M, Niimi P, Sturm G, Lin J, Moore AZ, Bandinelli S, Vinkers CH, Vermetten E, Rutten BPF, Geuze E, Okhuijsen-Pfeifer C, van der Horst MZ, Schreiter S, Gutwinski S, Luykx JJ, Picard M, Ferrucci L, Crimmins EM, Boks MP, Hägg S, Hu-Seliger TT, Levine ME. Nat Aging. 2022 Jul; 2022 Jul 15. PMID: 36277076.
Modeling pandemic to endemic patterns of SARS-CoV-2 transmission using parameters estimated from animal model data.Mullin S, Wyk BV, Asher JL, Compton SR, Allore HG, Zeiss CJ. PNAS Nexus. 2022 Jul; 2022 Jul 1. PMID: 35799833.
Alzheimer disease neuropathology in a patient previously treated with aducanumab.Plowey ED, Bussiere T, Rajagovindan R, Sebalusky J, Hamann S, von Hehn C, Castrillo-Viguera C, Sandrock A, Budd Haeberlein S, van Dyck CH, Huttner A. Acta Neuropathol. 2022 Jul; 2022 May 17. PMID: 35581440.
Neuropathological associations of limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) differ between the oldest-old and younger-old.Wang SJ, Guo Y, Ervin JF, Lusk JB, Luo S. Acta Neuropathol. 2022 Jul; 2022 May 12. PMID: 35551470.
Sex Differences for Clinical Correlates of Alzheimer's Pathology in People with Lewy Body Pathology.Bayram E, Coughlin DG, Litvan I. Mov Disord. 2022 Jul; 2022 May 9. PMID: 35531707.
Evaluating the Beijing Version of Montreal Cognitive Assessment for Identification of Cognitive Impairment in Monolingual Chinese American Older Adults.Hong Y, Zeng X, Zhu CW, Neugroschl J, Aloysi A, Sano M, Li C. J Geriatr Psychiatry Neurol. 2022 Jul; 2021 Aug 11. PMID: 34378450.
Prodromal Dementia With Lewy Bodies: Evolution of Symptoms and Predictors of Dementia Onset.Wyman-Chick KA, O'Keefe LR, Weintraub D, Armstrong MJ, Rosenbloom M, Martin PK, Barclay TR, Barrett MJ. J Geriatr Psychiatry Neurol. 2022 Jul; 2021 Jun 11. PMID: 34114509.
Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer's disease cognition.Johnson NR, Wang AC, Coughlan C, Sillau S, Lucero E, Viltz L, Markham N, Allen C, Dhanasekaran AR, Chial HJ, Potter H. Alzheimers Res Ther. 2022 Jun 29; 2022 Jun 29. PMID: 35768831.
Trajectories of Cognitive Decline in Brain Donors With Autopsy-Confirmed Alzheimer Disease and Cerebrovascular Disease.Frank B, Ally M, Tripodis Y, Puzo C, Labriola C, Hurley L, Martin B, Palmisano J, Chan L, Steinberg E, Turk K, Budson A, O'Connor M, Au R, Qiu WQ, Goldstein L, Kukull W, Kowall N, Killiany R, Stern R, Stein T, McKee A, Mez J, Alosco M. Neurology. 2022 Jun 14; 2022 Apr 20. PMID: 35444054.
Association of Cardiovascular Health Metrics with Dementia in Rural Chinese Older Adults: A Population-Based Study.Han X, Wang Y, Jiang Z, Li Y, Dong Y, Cong L, Hou T, Liang Y, Laukka EJ, Du Y, Qiu C. Clin Interv Aging. 2022; 2022 Jun 10. PMID: 35711676.
Imaging of Synaptic Density in Neurodegenerative Disorders.Carson RE, Naganawa M, Toyonaga T, Koohsari S, Yang Y, Chen MK, Matuskey D, Finnema SJ. J Nucl Med. 2022 Jun. PMID: 35649655.
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q.Spurrier J, Nicholson L, Fang XT, Stoner AJ, Toyonaga T, Holden D, Siegert TR, Laird W, Allnutt MA, Chiasseu M, Brody AH, Takahashi H, Nies SH, Pérez-Cañamás A, Sadasivam P, Lee S, Li S, Zhang L, Huang YH, Carson RE, Cai Z, Strittmatter SM. Sci Transl Med. 2022 Jun; 2022 Jun 1. PMID: 35648810.
Trajectories of cognitive functioning in later life: Disparities by race/ethnicity, educational attainment, sex, and multimorbidity combinations.Quiñones AR, Chen S, Nagel CL, Botoseneanu A, Allore HG, Newsom JT, Thielke S, Kaye J. SSM Popul Health. 2022 Jun; 2022 Apr 4. PMID: 35402685.
Comprehensive Evaluation of the Functional Activities Questionnaire (FAQ) and Its Reliability and Validity.González DA, Gonzales MM, Resch ZJ, Sullivan AC, Soble JR. Assessment. 2022 Jun; 2021 Feb 5. PMID: 33543638.
Progression to Dementia or Reversion to Normal Cognition in Mild Cognitive Impairment as a Function of Late-Onset Neuropsychiatric Symptoms.McGirr A, Nathan S, Ghahremani M, Gill S, Smith EE, Ismail Z. Neurology. 2022 May 24; 2022 Mar 29. PMID: 35351783.
Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment.Li Z, Heckman MG, Kanekiyo T, Martens YA, Day GS, Vassilaki M, Liu CC, Bennett DA, Petersen RC, Zhao N, Bu G. Neurology. 2022 May 17; 2022 Mar 21. PMID: 35314499.
Adaptive data-driven motion detection and optimized correction for brain PET.Revilla EM, Gallezot JD, Naganawa M, Toyonaga T, Fontaine K, Mulnix T, Onofrey JA, Carson RE, Lu Y. Neuroimage. 2022 May 15; 2022 Mar 4. PMID: 35257856.
Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy.Brody AH, Nies SH, Guan F, Smith LM, Mukherjee B, Salazar SA, Lee S, Lam TKT, Strittmatter SM. Mol Neurodegener. 2022 May 3; 2022 May 3. PMID: 35501917.
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models.Iyaswamy A, Wang X, Krishnamoorthi S, Kaliamoorthy V, Sreenivasmurthy SG, Kumar Durairajan SS, Song JX, Tong BC, Zhu Z, Su CF, Liu J, Cheung KH, Lu JH, Tan JQ, Li HW, Wong MS, Li M. Redox Biol. 2022 May; 2022 Mar 8. PMID: 35286997.
Association and interaction of TOMM40 and PVRL2 with plasma amyloid-β and Alzheimer's disease among Chinese older adults: a population-based study.Liang X, Liu C, Liu K, Cong L, Wang Y, Liu R, Fa W, Tian N, Cheng Y, Wang N, Hou T, Du Y, Qiu C. Neurobiol Aging. 2022 May; 2022 Jan 5. PMID: 35093267.
Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort.Guan Y, Ebrahimzadeh SA, Cheng CH, Chen W, Leung T, Bigornia S, Palacios N, Garelnabi MO, Scott T, Bhadelia R, Tucker KL, Koo BB. Neurology. 2022 Apr 12; 2022 Mar 30. PMID: 35354581.
Limbic-Predominant Age-Related TDP-43 Encephalopathy: Medical and Pathologic Factors Associated With Comorbid Hippocampal Sclerosis.Gauthreaux KM, Teylan MA, Katsumata Y, Mock C, Culhane JE, Chen YC, Chan KCG, Fardo DW, Dugan AJ, Cykowski MD, Jicha GA, Kukull WA, Nelson PT. Neurology. 2022 Apr 5; 2022 Feb 4. PMID: 35121671.
Examining heterogeneity in depression symptoms and associations with cognition and everyday function in MCI.Divers R, Robinson A, Miller L, Davis K, Reed C, Calamia M. J Clin Exp Neuropsychol. 2022 Apr; 2022 Jul 21. PMID: 35862574.
KIBRA regulates amyloid β metabolism by controlling extracellular vesicles secretion.Han X, Wang C, Song L, Wang X, Tang S, Hou T, Liu C, Liang X, Qiu C, Wang Y, Du Y. EBioMedicine. 2022 Apr; 2022 Apr 1. PMID: 35367771.
An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns.Jin B, Capra JA, Benchek P, Wheeler N, Naj AC, Hamilton-Nelson KL, Farrell JJ, Leung YY, Kunkle B, Vadarajan B, Schellenberg GD, Mayeux R, Wang LS, Farrer LA, Pericak-Vance MA, Martin ER, Haines JL, Crawford DC, Bush WS. Genome Res. 2022 Apr; 2022 Feb 24. PMID: 35210353.
Risk Factors of Skilled Nursing Facility Admissions and the Interrelation With Hospitalization and Amount of Informal Caregiving Received.Cao Y, Allore H, Gutman R, Vander Wyk B, Jørgensen TSH. Med Care. 2022 Apr 1. PMID: 35149662.
Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer's Disease.Guan X, Iyaswamy A, Sreenivasmurthy SG, Su C, Zhu Z, Liu J, Kan Y, Cheung KH, Lu J, Tan J, Li M. Int J Mol Sci. 2022 Mar 25; 2022 Mar 25. PMID: 35408965.
PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging.Toyonaga T, Fesharaki-Zadeh A, Strittmatter SM, Carson RE, Cai Z. Front Neurosci. 2022; 2022 Mar 8. PMID: 35345546.
Difficulty and help with activities of daily living among older adults living alone during the COVID-19 pandemic: a multi-country population-based study.Chen S, Jones LA, Jiang S, Jin H, Dong D, Chen X, Wang D, Zhang Y, Xiang L, Zhu A, Cardinal RN. BMC Geriatr. 2022 Mar 4; 2022 Mar 4. PMID: 35246064.
Association of Variation in Behavioral Symptoms With Initial Cognitive Phenotype in Adults With Dementia Confirmed by Neuropathology.Pillai JA, Bena J, Rothenberg K, Boron B, Leverenz JB. JAMA Netw Open. 2022 Mar 1; 2022 Mar 1. PMID: 35238936.
The vascular risk factors and vascular neuropathology in subjects with autopsy-confirmed dementia with Lewy bodies.Chen ZC, Gan J, Yang Y, Meng Q, Han J, Ji Y. Int J Geriatr Psychiatry. 2022 Mar. PMID: 35128731.
Optimizing the surgical management of MRI-negative epilepsy in the neuromodulation era.McGrath H, Mandel M, Sandhu MRS, Lamsam L, Adenu-Mensah N, Farooque P, Spencer DD, Damisah EC. Epilepsia Open. 2022 Mar; 2022 Feb 1. PMID: 35038792.
Association of entorhinal cortical tau deposition and hippocampal synaptic density in older individuals with normal cognition and early Alzheimer's disease.Mecca AP, Chen MK, O'Dell RS, Naganawa M, Toyonaga T, Godek TA, Harris JE, Bartlett HH, Zhao W, Banks ER, Ni GS, Rogers K, Gallezot JD, Ropchan J, Emery PR, Nabulsi NB, Vander Wyk BC, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Neurobiol Aging. 2022 Mar; 2021 Nov 20. PMID: 34963063.
Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes.Dugan AJ, Nelson PT, Katsumata Y, Shade LMP, Teylan MA, Boehme KL, Mukherjee S, Kauwe JSK, Hohman TJ, Schneider JA, Fardo DW. Neurobiol Aging. 2022 Mar; 2021 Oct 29. PMID: 34852950.
Functional Disabilities and Psychiatric Symptoms in Primary Progressive Aphasia.Morrow CB, Leoutsakos JS, Onyike CU. Am J Geriatr Psychiatry. 2022 Mar; 2021 Jul 28. PMID: 34412935.
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease.Tong BC, Wu AJ, Huang AS, Dong R, Malampati S, Iyaswamy A, Krishnamoorthi S, Sreenivasmurthy SG, Zhu Z, Su C, Liu J, Song J, Lu JH, Tan J, Pan W, Li M, Cheung KH. Autophagy. 2022 Mar; 2021 Jul 27. PMID: 34313551.
Association Between Potentially Inappropriate Medications and 30-Day Post-Hospital Discharge Outcomes in US Veterans.Allore HG, Gnjidic D, Skanderson M, Han L. Ann Pharmacother. 2022 Mar; 2021 Jul 20. PMID: 34282638.
Validation of the National Alzheimer's Coordinating Center (NACC) Lewy Body Disease Module neuropsychological tests.Rahman-Filipiak A, Sadaghiyani S, Davis K, Bhaumik AK, Paulson HL, Giordani B, Hampstead BM. Alzheimers Dement (Amst). 2022; 2022 Feb 9. PMID: 35155734.
Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping.Belloy ME, Eger SJ, Le Guen Y, Damotte V, Ahmad S, Ikram MA, Ramirez A, Tsolaki AC, Rossi G, Jansen IE, de Rojas I, Parveen K, Sleegers K, Ingelsson M, Hiltunen M, Amin N, Andreassen O, Sánchez-Juan P, Kehoe P, Amouyel P, Sims R, Frikke-Schmidt R, van der Flier WM, Lambert JC, He Z, Han SS, Napolioni V, Greicius MD. Alzheimers Res Ther. 2022 Feb 4; 2022 Feb 4. PMID: 35120553.
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells.Franjic D, Skarica M, Ma S, Arellano JI, Tebbenkamp ATN, Choi J, Xu C, Li Q, Morozov YM, Andrijevic D, Vrselja Z, Spajic A, Santpere G, Li M, Zhang S, Liu Y, Spurrier J, Zhang L, Gudelj I, Rapan L, Takahashi H, Huttner A, Fan R, Strittmatter SM, Sousa AMM, Rakic P, Sestan N. Neuron. 2022 Feb 2; 2021 Nov 18. PMID: 34798047.
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition.Sreenivasmurthy SG, Iyaswamy A, Krishnamoorthi S, Senapati S, Malampati S, Zhu Z, Su CF, Liu J, Guan XJ, Tong BC, Cheung KH, Tan JQ, Lu JH, Durairajan SSK, Song JX, Li M. Phytomedicine. 2022 Feb; 2021 Dec 8. PMID: 34936968.
Diagnostic accuracy and differential associations between ratings of functioning and neuropsychological performance in non-Hispanic Black and White older adults.Graves LV, Edmonds EC, Thomas KR, Weigand AJ, Cooper S, Stickel AM, Zlatar ZZ, Clark AL, Bondi MW. Clin Neuropsychol. 2022 Feb; 2021 Sep 9. PMID: 34499580.
Examination of race and gender differences in predictors of neuropsychological decline and development of Alzheimer's disease.Johnson EEH, Alexander C, Lee GJ, Angers K, Ndiaye D, Suhr J. Clin Neuropsychol. 2022 Feb; 2021 Jul 5. PMID: 34218735.
Self-reported sleep characteristics associated with dementia among rural-dwelling Chinese older adults: a population-based study.Liu R, Tang S, Wang Y, Dong Y, Hou T, Ren Y, Cong L, Liu K, Qin Y, Sindi S, Du Y, Qiu C. BMC Neurol. 2022 Jan 3; 2022 Jan 3. PMID: 34979998.
Hypothalamic Functional Connectivity and Apathy in People with Alzheimer's Disease and Cognitively Normal Healthy Controls.Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. J Alzheimers Dis. 2022. PMID: 36314209.
Sex Modifies the Associations of APOEɛ4 with Neuropsychiatric Symptom Burden in Both At-Risk and Clinical Cohorts of Alzheimer's Disease.Dissanayake AS, Tan YB, Bowie CR, Butters MA, Flint AJ, Gallagher D, Golas AC, Herrmann N, Ismail Z, Kennedy JL, Kumar S, Lanctot KL, Mah L, Mulsant BH, Pollock BG, Rajji TK, Tau M, Maraj A, Churchill NW, Tsuang D, Schweizer TA, Munoz DG, Fischer CE. J Alzheimers Dis. 2022. PMID: 36314203.
Machine Learning Approach Predicts Probability of Time to Stage-Specific Conversion of Alzheimer's Disease.Wu X, Peng C, Nelson PT, Cheng Q. J Alzheimers Dis. 2022. PMID: 36189595.
Hyperorality in Frontotemporal Dementia: Cognitive and Psychiatric Symptom Profiles in Early-Stage Disease.Morrow CB, Chaney GS, Capuzzi D, Bakker A, Onyike CU, Kamath V. J Alzheimers Dis. 2022. PMID: 36093697.
Sleep Disturbances, Cognitive Status, and Biomarkers of Dementia.Zawar I, Mattos MK, Manning C, Quigg M. J Alzheimers Dis. 2022. PMID: 36031904.
Neuropathological and Clinical Correlates of Lewy Body Disease Survival by Race and Ethnicity in the National Alzheimer's Coordinating Center.Kurasz AM, De Wit L, Smith GE, Armstrong MJ. J Alzheimers Dis. 2022. PMID: 36031892.
Population Attributable Fractions for Modifiable Risk Factors of Incident Dementia in Cognitively Normal and Mild Cognitively Impaired Older Adults: Data from Two Cohort Studies.Wezeman SL, Uleman JF, Scarmeas N, Kosmidis MH, Dardiotis E, Peeters GMEEG, Olde Rikkert MGM. J Alzheimers Dis. 2022. PMID: 35871325.
Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease.Budd Haeberlein S, Aisen PS, Barkhof F, Chalkias S, Chen T, Cohen S, Dent G, Hansson O, Harrison K, von Hehn C, Iwatsubo T, Mallinckrodt C, Mummery CJ, Muralidharan KK, Nestorov I, Nisenbaum L, Rajagovindan R, Skordos L, Tian Y, van Dyck CH, Vellas B, Wu S, Zhu Y, Sandrock A. J Prev Alzheimers Dis. 2022. PMID: 35542991.
Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology.Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. Am J Alzheimers Dis Other Demen. 2022 Jan-Dec. PMID: 35357236.
Predictors of Mortality in Individuals with Dementia in the National Alzheimer's Coordinating Center.Armstrong MJ, Song S, Kurasz AM, Li Z. J Alzheimers Dis. 2022. PMID: 35253760.
Correlates of Conversion from Mild Cognitive Impairment to Dementia with Lewy Bodies: Data from the National Alzheimer's Coordinating Center.Payne S, Shofer JB, Shutes-David A, Li G, Jankowski A, Dean P, Tsuang D. J Alzheimers Dis. 2022. PMID: 35213374.
Neuropsychiatric Inventory-Questionnaire Assessed Nighttime Behaviors in Cognitively Asymptomatic Patients with Pathologically Confirmed Alzheimer's Disease Predict More Rapid Cognitive Deterioration.Atayde AL, Fischer CE, Schweizer TA, Munoz DG. J Alzheimers Dis. 2022. PMID: 35180114.
Predictors of Life Expectancy in Autopsy-Confirmed Alzheimer's Disease.Schaffert J, LoBue C, Hynan LS, Hart J, Rossetti H, Carlew AR, Lacritz L, White CL, Cullum CM. J Alzheimers Dis. 2022. PMID: 35034898.
Caring for the Caregivers: An Alzheimer Disease Research Center Call to Action.Cothran FA, Alto R, Tomaszewski Farias S, Johnson DK, Lara E, Whitmer RA, DeCarli C, Meyer OL. Alzheimer Dis Assoc Disord. 2022 Jan-Mar 01. PMID: 34966023.
Cerebral Volumetric Correlates of Apathy in Alzheimer's Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort.Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. J Alzheimers Dis. 2022. PMID: 34924392.
TREM2 Deficiency Disrupts Network Oscillations Leading to Epileptic Activity and Aggravates Amyloid-β-Related Hippocampal Pathophysiology in Mice.Stoiljkovic M, Gutierrez KO, Kelley C, Horvath TL, Hajós M. J Alzheimers Dis. 2022. PMID: 34120899.
Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging.Jiang Y, Zhou X, Ip FC, Chan P, Chen Y, Lai NCH, Cheung K, Lo RMN, Tong EPS, Wong BWY, Chan ALT, Mok VCT, Kwok TCY, Mok KY, Hardy J, Zetterberg H, Fu AKY, Ip NY. Alzheimers Dement. 2022 Jan; 2021 May 25. PMID: 34032364.

2021

Animal Models of COVID-19 II. Comparative Immunology.Veenhuis RT, Zeiss CJ. ILAR J. 2021 Dec 31. PMID: 33914873.
Animal Models of COVID-19. I. Comparative Virology and Disease Pathogenesis.Zeiss CJ, Compton S, Veenhuis RT. ILAR J. 2021 Dec 31. PMID: 33836527.
A whole-process interpretable and multi-modal deep reinforcement learning for diagnosis and analysis of Alzheimer's disease(∗).Zhang Q, Du Q, Liu G. J Neural Eng. 2021 Dec 13; 2021 Dec 13. PMID: 34753116.
Comparative Milestones in Rodent and Human Postnatal Central Nervous System Development.Zeiss CJ. Toxicol Pathol. 2021 Dec; 2021 Sep 26. PMID: 34569375.
Estimating Progression Rates Across the Spectrum of Alzheimer's Disease for Amyloid-Positive Individuals Using National Alzheimer's Coordinating Center Data.Potashman M, Buessing M, Levitchi Benea M, Cummings J, Borson S, Pemberton-Ross P, Epstein AJ. Neurol Ther. 2021 Dec; 2021 Aug 24. PMID: 34431074.
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease.Libiger O, Shaw LM, Watson MH, Nairn AC, Umaña KL, Biarnes MC, Canet-Avilés RM, Jack CR Jr, Breton YA, Cortes L, Chelsky D, Spellman DS, Baker SA, Raghavan N, Potter WZ. Alzheimers Dement. 2021 Dec; 2021 May 13. PMID: 33984181.
Cognitive dysfunction and cerebral volumetric deficits in individuals with Alzheimer's disease, alcohol use disorder, and dual diagnosis.Zhornitsky S, Chaudhary S, Le TM, Chen Y, Zhang S, Potvin S, Chao HH, van Dyck CH, Li CR. Psychiatry Res Neuroimaging. 2021 Nov 30; 2021 Aug 29. PMID: 34482052.
Modeling SARS-CoV-2 propagation using rat coronavirus-associated shedding and transmission.Zeiss CJ, Asher JL, Vander Wyk B, Allore HG, Compton SR. PLoS One. 2021; 2021 Nov 23. PMID: 34813610.
Differences in Symptomatic Presentation and Cognitive Performance Among Participants With LATE-NC Compared to FTLD-TDP.Teylan MA, Mock C, Gauthreaux K, Culhane JE, Jicha G, Chen YC, Chan KCG, Kukull WA, Nelson PT, Katsumata Y. J Neuropathol Exp Neurol. 2021 Nov 19; 2021 Oct 1. PMID: 34597386.
Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial.Mintzer J, Lanctôt KL, Scherer RW, Rosenberg PB, Herrmann N, van Dyck CH, Padala PR, Brawman-Mintzer O, Porsteinsson AP, Lerner AJ, Craft S, Levey AI, Burke W, Perin J, Shade D. JAMA Neurol. 2021 Nov 1. PMID: 34570180.
Recruitment of a multi-site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial.Shadyab AH, LaCroix AZ, Feldman HH, van Dyck CH, Okonkwo OC, Tam SP, Fairchild JK, Welsh-Bohmer KA, Matthews G, Bennett D, Shadyab AA, Schafer KA, Morrison RH, Kipperman SA, Mason J, Tan D, Thomas RG, Cotman CW, Baker LD. Alzheimers Dement. 2021 Nov; 2021 Jul 23. PMID: 34297895.
Studies of aging nonhuman primates illuminate the etiology of early-stage Alzheimer's-like neuropathology: An evolutionary perspective.Arnsten AFT, Datta D, Preuss TM. Am J Primatol. 2021 Nov; 2021 May 7. PMID: 33960505.
Changes in retinal multilayer thickness and vascular network of patients with Alzheimer's disease.Mei X, Qiu C, Zhou Q, Chen Z, Chen Y, Xu Z, Zou C. Biomed Eng Online. 2021 Oct 3; 2021 Oct 3. PMID: 34602087.
Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.Nies SH, Takahashi H, Herber CS, Huttner A, Chase A, Strittmatter SM. J Biol Chem. 2021 Oct; 2021 Sep 2. PMID: 34480901.
Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease.Iyaswamy A, Krishnamoorthi SK, Zhang H, Sreenivasmurthy SG, Zhu Z, Liu J, Su CF, Guan XJ, Wang ZY, Cheung KH, Song JX, Durairajan SSK, Li M. Phytomedicine. 2021 Oct; 2021 Jul 12. PMID: 34332287.
Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study.Dugan AJ, Nelson PT, Katsumata Y, Shade LMP, Boehme KL, Teylan MA, Cykowski MD, Mukherjee S, Kauwe JSK, Hohman TJ, Schneider JA, Fardo DW. Acta Neuropathol Commun. 2021 Sep 15; 2021 Sep 15. PMID: 34526147.
Neuropsychiatric symptoms in early stage of Alzheimer's and non-Alzheimer's dementia, and the risk of progression to severe dementia.Liew TM. Age Ageing. 2021 Sep 11. PMID: 33770167.
Comparative Value of Cholinesterase Inhibitors and Memantine in Persons with Moderate-to-Severe Alzheimer's Disease in the United States: A Cost-Effectiveness Analysis.Yunusa I, Alsahali S, Rane A, Eguale T. J Alzheimers Dis Rep. 2021; 2021 Sep 6. PMID: 34755044.
Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer's dementia.Xiong LY, Ouk M, Wu CY, Rabin JS, Lanctôt KL, Herrmann N, Black SE, Edwards JD, Swardfager W. Alzheimers Res Ther. 2021 Sep 3; 2021 Sep 3. PMID: 34479635.
Generation of synthetic PET images of synaptic density and amyloid from (18) F-FDG images using deep learning.Wang R, Liu H, Toyonaga T, Shi L, Wu J, Onofrey JA, Tsai YJ, Naganawa M, Ma T, Liu Y, Chen MK, Mecca AP, O'Dell RS, van Dyck CH, Carson RE, Liu C. Med Phys. 2021 Sep; 2021 Jul 27. PMID: 34224153.
Partial volume correction analysis for (11)C-UCB-J PET studies of Alzheimer's disease.Lu Y, Toyonaga T, Naganawa M, Gallezot JD, Chen MK, Mecca AP, van Dyck CH, Carson RE. Neuroimage. 2021 Sep; 2021 Jun 11. PMID: 34119639.
Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics.Carlyle BC, Kandigian SE, Kreuzer J, Das S, Trombetta BA, Kuo Y, Bennett DA, Schneider JA, Petyuk VA, Kitchen RR, Morris R, Nairn AC, Hyman BT, Haas W, Arnold SE. Neurobiol Aging. 2021 Sep; 2021 Apr 24. PMID: 34052751.
Effect of age on brain metabotropic glutamate receptor subtype 5 measured with [(18)F]FPEB PET.Mecca AP, Rogers K, Jacobs Z, McDonald JW, Michalak HR, DellaGioia N, Zhao W, Hillmer AT, Nabulsi N, Lim K, Ropchan J, Huang Y, Matuskey D, Esterlis I, Carson RE, van Dyck CH. Neuroimage. 2021 Sep; 2021 May 27. PMID: 34052464.
Comparison of [(11)C]UCB-J and [(18)F]FDG PET in Alzheimer's disease: A tracer kinetic modeling study.Chen MK, Mecca AP, Naganawa M, Gallezot JD, Toyonaga T, Mondal J, Finnema SJ, Lin SF, O'Dell RS, McDonald JW, Michalak HR, Vander Wyk B, Nabulsi NB, Huang Y, Arnsten AF, van Dyck CH, Carson RE. J Cereb Blood Flow Metab. 2021 Sep; 2021 Mar 24. PMID: 33757318.
How impaired is too impaired? Exploring futile neuropsychological test patterns as a function of dementia severity and cognitive screening scores.Kiselica AM, Johnson E, Benge JF. J Neuropsychol. 2021 Sep; 2021 Mar 3. PMID: 33655681.
Depression and Increased Risk of Alzheimer's Dementia: Longitudinal Analyses of Modifiable Risk and Sex-Related Factors.Kim D, Wang R, Kiss A, Bronskill SE, Lanctot KL, Herrmann N, Gallagher D. Am J Geriatr Psychiatry. 2021 Sep; 2021 Jan 6. PMID: 33455858.
Scalable and robust latent trajectory class analysis using artificial likelihood.Hart KR, Fei T, Hanfelt JJ. Biometrics. 2021 Sep; 2020 Sep 14. PMID: 32896901.
Gerstmann Syndrome Deconstructed by Cortical Stimulation.Vaddiparti A, McGrath H, Benjamin CFA, Sivaraju A, Spencer DD, Hirsch LJ, Damisah E, Quraishi IH. Neurology. 2021 Aug 31; 2021 Jun 29. PMID: 34187861.
Feasibility study for detection of retinal amyloid in clinical trials: The Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial.Ngolab J, Donohue M, Belsha A, Salazar J, Cohen P, Jaiswal S, Tan V, Gessert D, Korouri S, Aggarwal NT, Alber J, Johnson K, Jicha G, van Dyck C, Lah J, Salloway S, Sperling RA, Aisen PS, Rafii MS, Rissman RA. Alzheimers Dement (Amst). 2021; 2021 Aug 17. PMID: 34430703.
Identifying brain networks in synaptic density PET ((11)C-UCB-J) with independent component analysis.Fang XT, Toyonaga T, Hillmer AT, Matuskey D, Holmes SE, Radhakrishnan R, Mecca AP, van Dyck CH, D'Souza DC, Esterlis I, Worhunsky PD, Carson RE. Neuroimage. 2021 Aug 15; 2021 May 15. PMID: 34000404.
GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.Xu P, Chang JC, Zhou X, Wang W, Bamkole M, Wong E, Bettayeb K, Jiang LL, Huang T, Luo W, Xu H, Nairn AC, Flajolet M, Ip NY, Li YM, Greengard P. J Exp Med. 2021 Aug 2; 2021 Jun 22. PMID: 34156424.
Aging biomarkers and the brain.Higgins-Chen AT, Thrush KL, Levine ME. Semin Cell Dev Biol. 2021 Aug; 2021 Jan 25. PMID: 33509689.
A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.Salloway S, Farlow M, McDade E, Clifford DB, Wang G, Llibre-Guerra JJ, Hitchcock JM, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, Cruchaga C, Goate AA, Perrin RJ, Xiong C, Li Y, Morris JC, Snider BJ, Mummery C, Surti GM, Hannequin D, Wallon D, Berman SB, Lah JJ, Jimenez-Velazquez IZ, Roberson ED, van Dyck CH, Honig LS, Sánchez-Valle R, Brooks WS, Gauthier S, Galasko DR, Masters CL, Brosch JR, Hsiung GR, Jayadev S, Formaglio M, Masellis M, Clarnette R, Pariente J, Dubois B, Pasquier F, Jack CR Jr, Koeppe R, Snyder PJ, Aisen PS, Thomas RG, Berry SM, Wendelberger BA, Andersen SW, Holdridge KC, Mintun MA, Yaari R, Sims JR, Baudler M, Delmar P, Doody RS, Fontoura P, Giacobino C, Kerchner GA, Bateman RJ. Nat Med. 2021 Jul; 2021 Jun 21. PMID: 34155411.
Therapy for Alzheimer's disease: Missing targets and functional markers?Stoiljkovic M, Horvath TL, Hajós M. Ageing Res Rev. 2021 Jul; 2021 Mar 9. PMID: 33711510.
Quantitative and qualitative features of executive dysfunction in frontotemporal and Alzheimer's dementia.Kiselica AM, Benge JF. Appl Neuropsychol Adult. 2021 Jul-Aug; 2019 Aug 19. PMID: 31424275.
Pleiotropic effects of telomere length loci with brain morphology and brain tissue expression.Pathak GA, Wendt FR, Levey DF, Mecca AP, van Dyck CH, Gelernter J, Polimanti R. Hum Mol Genet. 2021 Jun 26. PMID: 33831179.
Knowledge and perceptions of Alzheimer's disease in three ethnic groups of younger adults in the United Kingdom.Kafadar AH, Barrett C, Cheung KL. BMC Public Health. 2021 Jun 12; 2021 Jun 12. PMID: 34118921.
Visit-to-Visit Blood Pressure Variability, Neuropathology, and Cognitive Decline.Ma Y, Blacker D, Viswanathan A, van Veluw SJ, Bos D, Vernooij MW, Hyman BT, Tzourio C, Das S, Hofman A. Neurology. 2021 Jun 8; 2021 Apr 26. PMID: 33903194.
Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice.Qiu C, Albayram O, Kondo A, Wang B, Kim N, Arai K, Tsai CY, Bassal MA, Herbert MK, Washida K, Angeli P, Kozono S, Stucky JE, Baxley S, Lin YM, Sun Y, Rotenberg A, Caldarone BJ, Bigio EH, Chen X, Tenen DG, Zeidel M, Lo EH, Zhou XZ, Lu KP. Sci Transl Med. 2021 Jun 2. PMID: 34078745.
Age-related calcium dysregulation linked with tau pathology and impaired cognition in non-human primates.Datta D, Leslie SN, Wang M, Morozov YM, Yang S, Mentone S, Zeiss C, Duque A, Rakic P, Horvath TL, van Dyck CH, Nairn AC, Arnsten AFT. Alzheimers Dement. 2021 Jun; 2021 Apr 7. PMID: 33829643.
Quantification of SV2A Binding in Rodent Brain Using [(18)F]SynVesT-1 and PET Imaging.Sadasivam P, Fang XT, Toyonaga T, Lee S, Xu Y, Zheng MQ, Spurrier J, Huang Y, Strittmatter SM, Carson RE, Cai Z. Mol Imaging Biol. 2021 Jun; 2020 Nov 30. PMID: 33258040.
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.Vattathil SM, Liu Y, Harerimana NV, Lori A, Gerasimov ES, Beach TG, Reiman EM, De Jager PL, Schneider JA, Bennett DA, Seyfried NT, Levey AI, Wingo AP, Wingo TS. Genes (Basel). 2021 May 26; 2021 May 26. PMID: 34073619.
Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease.Qian J, Betensky RA, Hyman BT, Serrano-Pozo A. Neurology. 2021 May 11; 2021 Mar 26. PMID: 33771840.
Age-at-Onset and APOE-Related Heterogeneity in Pathologically Confirmed Sporadic Alzheimer Disease.Smirnov DS, Galasko D, Hiniker A, Edland SD, Salmon DP. Neurology. 2021 May 4; 2021 Mar 15. PMID: 33722993.
Utility of MRI in the identification of hippocampal sclerosis of aging.Woodworth DC, Nguyen HL, Khan Z, Kawas CH, Corrada MM, Sajjadi SA. Alzheimers Dement. 2021 May; 2020 Dec 7. PMID: 33615673.
Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer's Disease.Jutten RJ, Sikkes SAM, Amariglio RE, Buckley RF, Properzi MJ, Marshall GA, Rentz DM, Johnson KA, Teunissen CE, Van Berckel BNM, Van der Flier WM, Scheltens P, Sperling RA, Papp KV. J Int Neuropsychol Soc. 2021 May; 2020 Oct 13. PMID: 33046162.
Neuropsychological impact of white matter hyperintensities in older adults without dementia.Chavda R, Cao JS, Benge JF. Appl Neuropsychol Adult. 2021 May-Jun; 2019 Jul 9. PMID: 31287337.
Age-Related Hearing Loss, Late-Life Depression, and Risk for Incident Dementia in Older Adults.Brewster KK, Hu MC, Zilcha-Mano S, Stein A, Brown PJ, Wall MM, Roose SP, Golub JS, Rutherford BR. J Gerontol A Biol Sci Med Sci. 2021 Apr 30. PMID: 32959064.
Amyloid-Associated Depression-or Not?van Dyck CH, O'Dell RS, Mecca AP. Biol Psychiatry. 2021 Apr 15. PMID: 33766236.
Regulation of Synaptic Transmission and Plasticity by Protein Phosphatase 1.Foley K, McKee C, Nairn AC, Xia H. J Neurosci. 2021 Apr 7. PMID: 33827970.
Traumatic brain injury alters neuropsychiatric symptomatology in all-cause dementia.Bray MJC, Richey LN, Bryant BR, Krieg A, Jahed S, Tobolowsky W, LoBue C, Peters ME. Alzheimers Dement. 2021 Apr; 2021 Jan 19. PMID: 33470043.
Psychotropic Medication and Cognitive, Functional, and Neuropsychiatric Outcomes in Alzheimer's Disease (AD).Oh ES, Rosenberg PB, Rattinger GB, Stuart EA, Lyketsos CG, Leoutsakos JS. J Am Geriatr Soc. 2021 Apr; 2020 Dec 31. PMID: 33382921.
Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).Staffaroni AM, Asken BM, Casaletto KB, Fonseca C, You M, Rosen HJ, Boxer AL, Elahi FM, Kornak J, Mungas D, Kramer JH. Alzheimers Dement. 2021 Apr; 2020 Nov 20. PMID: 33215852.
First-in-Human Evaluation of (18)F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A.Naganawa M, Li S, Nabulsi N, Henry S, Zheng MQ, Pracitto R, Cai Z, Gao H, Kapinos M, Labaree D, Matuskey D, Huang Y, Carson RE. J Nucl Med. 2021 Apr; 2020 Aug 28. PMID: 32859701.
The Association Between the Number of Neuropsychological Measures and the Base Rate of Low Scores.Oltra-Cucarella J, Sánchez-SanSegundo M, Rubio-Aparicio M, Arango-Lasprilla JC, Ferrer-Cascales R. Assessment. 2021 Apr; 2019 Jul 31. PMID: 31364385.
Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability.Nagayoshi Y, Chujo T, Hirata S, Nakatsuka H, Chen CW, Takakura M, Miyauchi K, Ikeuchi Y, Carlyle BC, Kitchen RR, Suzuki T, Katsuoka F, Yamamoto M, Goto Y, Tanaka M, Natsume K, Nairn AC, Suzuki T, Tomizawa K, Wei FY. Sci Adv. 2021 Mar; 2021 Mar 26. PMID: 33771871.
Gene- and age-informed screening for preclinical Alzheimer's disease trials.Spencer BE, Digma LA, Jennings RG, Brewer JB. Alzheimers Dement. 2021 Mar; 2020 Nov 23. PMID: 33226723.
Neuropsychiatric Presentations due to Traumatic Brain Injury in Cognitively Normal Older Adults.Mundluru J, Subhan A, Lo TWB, Churchill N, Fornazzari L, Munoz DG, Schweizer TA, Fischer CE. J Neurotrauma. 2021 Mar; 2020 Oct 20. PMID: 32977734.
Simplified Quantification of (11)C-UCB-J PET Evaluated in a Large Human Cohort.Naganawa M, Gallezot JD, Finnema SJ, Matuskey D, Mecca A, Nabulsi NB, Labaree D, Ropchan J, Malison RT, D'Souza DC, Esterlis I, Detyniecki K, van Dyck CH, Huang Y, Carson RE. J Nucl Med. 2021 Mar; 2020 Jul 9. PMID: 32646875.
Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.Staffaroni AM, Weintraub S, Rascovsky K, Rankin KP, Taylor J, Fields JA, Casaletto KB, Hillis AE, Lukic S, Gorno-Tempini ML, Heuer H, Teylan MA, Kukull WA, Miller BL, Boeve BF, Rosen HJ, Boxer AL, Kramer JH. Alzheimers Dement (Amst). 2021; 2021 Feb 20. PMID: 33665340.
Exosomes as Emerging Biomarker Tools in Neurodegenerative and Neuropsychiatric Disorders-A Proteomics Perspective.Mathew B, Mansuri MS, Williams KR, Nairn AC. Brain Sci. 2021 Feb 19; 2021 Feb 19. PMID: 33669482.
Unlocking Pericyte Function in the Adult Blood Brain Barrier One Cell at a Time.Nicoli S, Grutzendler J. Circ Res. 2021 Feb 19; 2021 Feb 18. PMID: 33600230.
The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor blockers and cognitive decline in Alzheimer's disease: the importance of blood-brain barrier penetration and APOE ε4 carrier status.Ouk M, Wu CY, Rabin JS, Jackson A, Edwards JD, Ramirez J, Masellis M, Swartz RH, Herrmann N, Lanctôt KL, Black SE, Swardfager W. Alzheimers Res Ther. 2021 Feb 11; 2021 Feb 11. PMID: 33573702.
Shared risk and protective factors between Alzheimer's disease and ischemic stroke: A population-based longitudinal study.Wang R, Qiu C, Dintica CS, Shang Y, Calderón Larrañaga A, Wang HX, Xu W. Alzheimers Dement. 2021 Feb; 2021 Feb 1. PMID: 33527694.
Author Correction: AgRP neurons control compulsive exercise and survival in an activity-based anorexia model.Miletta MC, Iyilikci O, Shanabrough M, Šestan-Peša M, Cammisa A, Zeiss CJ, Dietrich MO, Horvath TL. Nat Metab. 2021 Feb. PMID: 33495625.
Progression of neuropsychiatric symptoms in young-onset versus late-onset Alzheimer's disease.Gumus M, Multani N, Mack ML, Tartaglia MC. Geroscience. 2021 Feb; 2021 Jan 9. PMID: 33420706.
Cumulative health deficits, APOE genotype, and risk for later-life mild cognitive impairment and dementia.Ward DD, Wallace LMK, Rockwood K. J Neurol Neurosurg Psychiatry. 2021 Feb; 2020 Nov 13. PMID: 33188132.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association.Mecca AP, van Dyck CH. Alzheimers Dement. 2021 Feb; 2020 Oct 12. PMID: 33047474.
Robust parametric modeling of Alzheimer's disease progression.Mehdipour Ghazi M, Nielsen M, Pai A, Modat M, Jorge Cardoso M, Ourselin S, Sørensen L. Neuroimage. 2021 Jan 15; 2020 Oct 16. PMID: 33075562.
Sex as a Risk Factor for Developing Cognitive Impairments in National Alzheimer's Coordinating Center Participants.Wang G, Li W. J Alzheimers Dis Rep. 2021 Jan 11; 2021 Jan 11. PMID: 33681711.
Pain, Complex Chronic Conditions and Potential Inappropriate Medication in People with Dementia. Lessons Learnt for Pain Treatment Plans Utilizing Data from the Veteran Health Administration.Husebo BS, Kerns RD, Han L, Skanderson M, Gnjidic D, Allore HG. Brain Sci. 2021 Jan 11; 2021 Jan 11. PMID: 33440668.
Association of Aβ deposition and regional synaptic density in early Alzheimer's disease: a PET imaging study with [(11)C]UCB-J.O'Dell RS, Mecca AP, Chen MK, Naganawa M, Toyonaga T, Lu Y, Godek TA, Harris JE, Bartlett HH, Banks ER, Kominek VL, Zhao W, Nabulsi NB, Ropchan J, Ye Y, Vander Wyk BC, Huang Y, Arnsten AFT, Carson RE, van Dyck CH. Alzheimers Res Ther. 2021 Jan 5; 2021 Jan 5. PMID: 33402201.
Association Between Polygenic Risk Score and the Progression from Mild Cognitive Impairment to Alzheimer's Disease.Liu H, Lutz M, Luo S. J Alzheimers Dis. 2021. PMID: 34657885.
Longitudinal Body Weight Change, Visit-To-Visit Body Weight Fluctuation, and Cognitive Decline Among Older Adults.Lan YT, Blacker D, Yuan C, Chibnik LB, Hofman A, Ma Y. J Alzheimers Dis. 2021. PMID: 34569956.
UDSNB 3.0 Neuropsychological Test Norms in Older Adults from a Diverse Community: Results from the Einstein Aging Study (EAS).Wang C, Katz MJ, Chang KH, Qin J, Lipton RB, Zwerling JL, Sliwinski MJ, Derby CA, Rabin LA. J Alzheimers Dis. 2021. PMID: 34420967.
Antemortem Visit-To-Visit Blood Pressure Variability Predicts Cerebrovascular Lesion Burden in Autopsy-Confirmed Alzheimer's Disease.Sible IJ, Bangen KJ, Blanken AE, Ho JK, Nation DA. J Alzheimers Dis. 2021. PMID: 34250941.
Classification, Prediction, and Concordance of Cognitive and Functional Progression in Patients with Mild Cognitive Impairment in the United States: A Latent Class Analysis.Mouchet J, Betts KA, Georgieva MV, Ionescu-Ittu R, Butler LM, Teitsma X, Delmar P, Kulalert T, Zhu J, Lema N, Desai U. J Alzheimers Dis. 2021. PMID: 34219723.
Neuropsychological Equivalence of the Clinical Diagnosis of Mild Cognitive Impairment in the National Alzheimer's Coordinating Center Uniform Data Set and Alzheimer's Disease Neuroimaging Initiative.Kiselica AM, Benge JF. Dement Geriatr Cogn Disord. 2021; 2021 Jun 29. PMID: 34186536.
Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies.Karanth SD, Schmitt FA, Nelson PT, Katsumata Y, Kryscio RJ, Fardo DW, Harp JP, Abner EL. J Alzheimers Dis. 2021. PMID: 34057090.
Hypertension and Hypercholesterolemia Modify Dementia Risk in Relation to APOEɛ4 Status.Pillai JA, Kou L, Bena J, Penn L, Leverenz JB. J Alzheimers Dis. 2021. PMID: 33967045.
Association Between the APOEɛ2/ɛ4 Genotype and Alzheimer's Disease and Mild Cognitive Impairment Among African Americans.Ren D, Lopez OL, Lingler JH, Conley Y. J Alzheimers Dis. 2021. PMID: 33935088.
Fronto-temporal dementia risk gene TMEM106B has opposing effects in different lysosomal storage disorders.Perez-Canamas A, Takahashi H, Lindborg JA, Strittmatter SM. Brain Commun. 2021; 2020 Nov 16. PMID: 33796852.
Cigarette Smoking Status, Cigarette Exposure, and Duration of Abstinence Predicting Incident Dementia and Death: A Multistate Model Approach.Johnson AL, Nystrom NC, Piper ME, Cook J, Norton DL, Zuelsdorff M, Wyman MF, Flowers Benton S, Lambrou NH, O'Hara J, Chin NA, Asthana S, Carlsson C, Gleason CE. J Alzheimers Dis. 2021. PMID: 33646160.
Cognition at Each Stage of Lewy Body Disease with Co-occurring Alzheimer's Disease Pathology.Ryman SG, Yutsis M, Tian L, Henderson VW, Montine TJ, Salmon DP, Galasko D, Poston KL. J Alzheimers Dis. 2021. PMID: 33646154.
Age-Related Hearing Loss, Neuropsychological Performance, and Incident Dementia in Older Adults.Brewster KK, Hu MC, Wall MM, Brown PJ, Zilcha-Mano S, Roose SP, Stein A, Golub JS, Rutherford BR. J Alzheimers Dis. 2021. PMID: 33579835.
Mild Behavioral Impairment and Subjective Cognitive Decline Predict Cognitive and Functional Decline.Ismail Z, McGirr A, Gill S, Hu S, Forkert ND, Smith EE. J Alzheimers Dis. 2021. PMID: 33554909.
Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease.Arnsten AFT, Datta D, Del Tredici K, Braak H. Alzheimers Dement. 2021 Jan; 2020 Oct 19. PMID: 33075193.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA. JAMA Neurol. 2021 Jan 1. PMID: 33074286.
Clinical Profiles of Arteriolosclerosis and Alzheimer Disease at Mild Cognitive Impairment and Mild Dementia in a National Neuropathology Cohort.Yang D, Masurkar AV. Alzheimer Dis Assoc Disord. 2021 Jan-Mar 01. PMID: 32925200.
Factors predicting episodic memory changes in older adults with subjective cognitive decline: A longitudinal observational study.Ahn S, Mathiason MA, Lindquist R, Yu F. Geriatr Nurs. 2021 Jan-Feb; 2020 Sep 9. PMID: 32919799.
Alzheimer's disease biomarkers as predictors of trajectories of depression and apathy in cognitively normal individuals, mild cognitive impairment, and Alzheimer's disease dementia.Banning LCP, Ramakers IHGB, Rosenberg PB, Lyketsos CG, Leoutsakos JS. Int J Geriatr Psychiatry. 2021 Jan; 2020 Sep 11. PMID: 32869375.
Testing influences of APOE and BDNF genes and heart failure on cognitive function.Jung M, Apostolova LG, Gao S, Burney HN, Lai D, Foroud T, Saykin AJ, Pressler SJ. Heart Lung. 2021 Jan-Feb; 2020 Jul 20. PMID: 32703621.
Measuring Apathy in Alzheimer's Disease in the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): A Comparison of Instruments.Lanctôt KL, Scherer RW, Li A, Vieira D, Coulibaly H, Rosenberg PB, Herrmann N, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Burke WJ, Mintzer JE. Am J Geriatr Psychiatry. 2021 Jan; 2020 May 27. PMID: 32565008.
Neurobiologic Rationale for Treatment of Apathy in Alzheimer's Disease With Methylphenidate.van Dyck CH, Arnsten AFT, Padala PR, Brawman-Mintzer O, Lerner AJ, Porsteinsson AP, Scherer RW, Levey AI, Herrmann N, Jamil N, Mintzer JE, Lanctôt KL, Rosenberg PB. Am J Geriatr Psychiatry. 2021 Jan; 2020 May 5. PMID: 32461027.
Risk of mild cognitive impairment among older adults in the United States by ethnoracial group.Perales-Puchalt J, Gauthreaux K, Shaw A, McGee JL, Teylan MA, Chan KCG, Rascovsky K, Kukull WA, Vidoni ED. Int Psychogeriatr. 2021 Jan; 2020 Jan 17. PMID: 31948505.

2020

Recent Consanguinity and Outbred Autozygosity Are Associated With Increased Risk of Late-Onset Alzheimer's Disease.Napolioni V, Scelsi MA, Khan RR, Altmann A, Greicius MD. Front Genet. 2020; 2021 Jan 29. PMID: 33584820.
Evaluating the Alzheimer's disease data landscape.Birkenbihl C, Salimi Y, Domingo-Fernándéz D, Lovestone S, Fröhlich H, Hofmann-Apitius M. Alzheimers Dement (N Y). 2020; 2020 Dec 16. PMID: 33344750.
[Association between periodontitis and Alzheimer disease: a meta analysis].Qiu C, Zhou W, Shi WT, Song ZC. Shanghai Kou Qiang Yi Xue. 2020 Dec. PMID: 33778838.
Relationships between memory decline and the use of metformin or DPP4 inhibitors in people with type 2 diabetes with normal cognition or Alzheimer's disease, and the role APOE carrier status.Wu CY, Ouk M, Wong YY, Anita NZ, Edwards JD, Yang P, Shah BR, Herrmann N, Lanctôt KL, Kapral MK, MacIntosh BJ, Rabin JS, Black SE, Swardfager W. Alzheimers Dement. 2020 Dec; 2020 Aug 16. PMID: 32803865.
Determinants of Sleep Medication Use among Participants in the National Alzheimer's Coordinating Center Uniform Data Set.Moloney M, Oh G, Moga DC. J Appl Gerontol. 2020 Dec; 2019 Nov 20. PMID: 31747852.
Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores.Dodge HH, Goldstein FC, Wakim NI, Gefen T, Teylan M, Chan KCG, Kukull WA, Barnes LL, Giordani B, Hughes TM, Kramer JH, Loewenstein DA, Marson DC, Mungas DM, Mattek N, Sachs BC, Salmon DP, Willis-Parker M, Welsh-Bohmer KA, Wild KV, Morris JC, Weintraub S. Alzheimers Dement (N Y). 2020; 2020 Nov 24. PMID: 33283037.
Differential Involvement of the Locus Coeruleus in Early- and Late-Onset Alzheimer's Disease: A Potential Mechanism of Clinical Differences?Bolton CJ, Tam JW. medRxiv. 2020 Nov 4; 2020 Nov 4. PMID: 33173930.
AgRP neurons control compulsive exercise and survival in an activity-based anorexia model.Miletta MC, Iyilikci O, Shanabrough M, Šestan-Peša M, Cammisa A, Zeiss CJ, Dietrich MO, Horvath TL. Nat Metab. 2020 Nov; 2020 Oct 26. PMID: 33106687.
D-CARE: The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System-Based Versus Community-Based Dementia Care Versus Usual Dementia Care.Reuben DB, Gill TM, Stevens A, Williamson J, Volpi E, Lichtenstein M, Jennings LA, Tan Z, Evertson L, Bass D, Weitzman L, Carnie M, Wilson N, Araujo K, Charpentier P, Meng C, Greene EJ, Dziura J, Liu J, Unger E, Yang M, Currie K, Lenoir KM, Green AS, Abraham S, Vernon A, Samper-Ternent R, Raji M, Hirst RM, Galloway R, Finney GR, Ladd I, Rahm AK, Borek P, Peduzzi P. J Am Geriatr Soc. 2020 Nov; 2020 Oct 6. PMID: 32949145.
Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in.Chiasseu M, Fesharaki-Zadeh A, Saito T, Saido TC, Strittmatter SM. Neurobiol Dis. 2020 Nov; 2020 Aug 25. PMID: 32858147.
Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy.Katsumata Y, Abner EL, Karanth S, Teylan MA, Mock CN, Cykowski MD, Lee EB, Boehme KL, Mukherjee S, Kauwe JSK, Kryscio RJ, Schmitt FA, Fardo DW, Nelson PT. Acta Neuropathol. 2020 Nov; 2020 Aug 14. PMID: 32797255.
Network structures and temporal stability of self- and informant-rated affective symptoms in Alzheimer's disease.Saari TT, Hallikainen I, Hintsa T, Koivisto AM. J Affect Disord. 2020 Nov 1; 2020 Jul 19. PMID: 32771860.
Predictors of Residential Care Admission in Community-Dwelling Older People With Dementia.Jamieson H, Abey-Nesbit R, Nishtala PS, Allore H, Han L, Deely JM, Pickering JW. J Am Med Dir Assoc. 2020 Nov; 2020 Jul 6. PMID: 32646821.
Phosphodiesterase PDE4D Is Decreased in Frontal Cortex of Aged Rats and Positively Correlated With Working Memory Performance and Inversely Correlated With PKA Phosphorylation of Tau.Leslie SN, Datta D, Christensen KR, van Dyck CH, Arnsten AFT, Nairn AC. Front Aging Neurosci. 2020; 2020 Oct 28. PMID: 33192469.
Multi-time-point data preparation robustly reveals MCI and dementia risk factors.Kaur D, Bucholc M, Finn DP, Todd S, Wong-Lin K, McClean PL. Alzheimers Dement (Amst). 2020; 2020 Oct 14. PMID: 33088897.
Underlying features of epigenetic aging clocks in vivo and in vitro.Liu Z, Leung D, Thrush K, Zhao W, Ratliff S, Tanaka T, Schmitz LL, Smith JA, Ferrucci L, Levine ME. Aging Cell. 2020 Oct; 2020 Sep 15. PMID: 32930491.
ADNC-RS, a clinical-genetic risk score, predicts Alzheimer's pathology in autopsy-confirmed Parkinson's disease and Dementia with Lewy bodies.Dai DL, Tropea TF, Robinson JL, Suh E, Hurtig H, Weintraub D, Van Deerlin V, Lee EB, Trojanowski JQ, Chen-Plotkin AS. Acta Neuropathol. 2020 Oct; 2020 Aug 4. PMID: 32749525.
Seizure occurrence and related mortality in dementia with Lewy bodies.Marawar R, Wakim N, Albin RL, Dodge H. Epilepsy Behav. 2020 Oct; 2020 Jul 18. PMID: 32693380.
Seizures in Alzheimer's disease are highly recurrent and associated with a poor disease course.Vöglein J, Ricard I, Noachtar S, Kukull WA, Dieterich M, Levin J, Danek A. J Neurol. 2020 Oct; 2020 Jun 2. PMID: 32488295.
Active case finding of dementia in ambulatory care settings: a comparison of three strategies.Liew TM. Eur J Neurol. 2020 Oct; 2020 Jun 16. PMID: 32441837.
Clinician-judged hearing impairment and associations with neuropathologic burden.Brenowitz WD, Besser LM, Kukull WA, Keene CD, Glymour MM, Yaffe K. Neurology. 2020 Sep 22; 2020 Aug 5. PMID: 32759190.
Association of APOE e2 genotype with Alzheimer's and non-Alzheimer's neurodegenerative pathologies.Goldberg TE, Huey ED, Devanand DP. Nat Commun. 2020 Sep 18; 2020 Sep 18. PMID: 32948752.
A Pentacyclic Triterpene from Ligustrum lucidum Targets γ-Secretase.Luo W, Ip FCF, Fu G, Cheung K, Tian Y, Hu Y, Sinha A, Cheng EYL, Wu X, Bustos V, Greengard P, Li YM, Sinha SC, Ip NY. ACS Chem Neurosci. 2020 Sep 16; 2020 Sep 3. PMID: 32786303.
Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer's disease neuropathology.Thomas DX, Bajaj S, McRae-McKee K, Hadjichrysanthou C, Anderson RM, Collinge J. Sci Rep. 2020 Sep 3; 2020 Sep 3. PMID: 32883971.
Health-care use and cost for multimorbid persons with dementia in the National Health and Aging Trends Study.MacNeil-Vroomen JL, Thompson M, Leo-Summers L, Marottoli RA, Tai-Seale M, Allore HG. Alzheimers Dement. 2020 Sep; 2020 Jul 30. PMID: 32729984.
Impact of Anticholinergic Burden on Cognitive Performance: A Cohort Study of Community-Dwelling Older Adults.Nishtala PS, Allore H, Han L, Jamieson HA, Hilmer SN, Chyou TY. J Am Med Dir Assoc. 2020 Sep; 2020 May 10. PMID: 32402780.
Classification of Alzheimer's Disease and Mild Cognitive Impairment Based on Cortical and Subcortical Features from MRI T1 Brain Images Utilizing Four Different Types of Datasets.Toshkhujaev S, Lee KH, Choi KY, Lee JJ, Kwon GR, Gupta Y, Lama RK. J Healthc Eng. 2020; 2020 Aug 31. PMID: 32952988.
Factors Predicting the Onset of Amnestic Mild Cognitive Impairment or Alzheimer's Dementia in Persons With Subjective Cognitive Decline.Ahn S, Mathiason MA, Salisbury D, Yu F. J Gerontol Nurs. 2020 Aug 1. PMID: 32936925.
Cutaneous and Pulmonary Mucormycosis in Rag1- and Il2rg-deficient Rats.Sarfaty AE, Compton SR, Smith PC, Zeiss CJ. Comp Med. 2020 Aug 1; 2020 Jul 31. PMID: 32736665.
Diabetes as a Risk Factor for Abnormal Cognition Development.Wang G, Li W. J Alzheimers Dis Rep. 2020 Jul 6; 2020 Jul 6. PMID: 32904673.
World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia.Kivipelto M, Mangialasche F, Snyder HM, Allegri R, Andrieu S, Arai H, Baker L, Belleville S, Brodaty H, Brucki SM, Calandri I, Caramelli P, Chen C, Chertkow H, Chew E, Choi SH, Chowdhary N, Crivelli L, Torre R, Du Y, Dua T, Espeland M, Feldman HH, Hartmanis M, Hartmann T, Heffernan M, Henry CJ, Hong CH, Håkansson K, Iwatsubo T, Jeong JH, Jimenez-Maggiora G, Koo EH, Launer LJ, Lehtisalo J, Lopera F, Martínez-Lage P, Martins R, Middleton L, Molinuevo JL, Montero-Odasso M, Moon SY, Morales-Pérez K, Nitrini R, Nygaard HB, Park YK, Peltonen M, Qiu C, Quiroz YT, Raman R, Rao N, Ravindranath V, Rosenberg A, Sakurai T, Salinas RM, Scheltens P, Sevlever G, Soininen H, Sosa AL, Suemoto CK, Tainta-Cuezva M, Velilla L, Wang Y, Whitmer R, Xu X, Bain LJ, Solomon A, Ngandu T, Carrillo MC. Alzheimers Dement. 2020 Jul; 2020 Jul 5. PMID: 32627328.
Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy.Tang SJ, Fesharaki-Zadeh A, Takahashi H, Nies SH, Smith LM, Luo A, Chyung A, Chiasseu M, Strittmatter SM. Acta Neuropathol Commun. 2020 Jul 1; 2020 Jul 1. PMID: 32611392.
Expanded Demographic Norms for Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set.Sachs BC, Steenland K, Zhao L, Hughes TM, Weintraub S, Dodge HH, Barnes LL, Craft S, Parker ML, Goldstein FC. Alzheimer Dis Assoc Disord. 2020 Jul-Sep. PMID: 32483017.
In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET.Mecca AP, Chen MK, O'Dell RS, Naganawa M, Toyonaga T, Godek TA, Harris JE, Bartlett HH, Zhao W, Nabulsi NB, Wyk BCV, Varma P, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Alzheimers Dement. 2020 Jul; 2020 May 13. PMID: 32400950.
Comparing patient and informant ratings of depressive symptoms in various stages of Alzheimer's disease.Gold D, Rosowsky E, Piryatinsky I, Sinclair SJ. Neuropsychology. 2020 Jul; 2020 Mar 19. PMID: 32191055.
The Uniform Dataset 3.0 Neuropsychological Battery: Factor Structure, Invariance Testing, and Demographically Adjusted Factor Score Calculation.Kiselica AM, Webber TA, Benge JF. J Int Neuropsychol Soc. 2020 Jul; 2020 Feb 17. PMID: 32063246.
Associations of Race-Ethnicity and History of Traumatic Brain Injury With Age at Onset of Alzheimer's Disease.Bailey KC, Burmaster SA, Schaffert J, LoBue C, Vela D, Rossetti H, Cullum CM. J Neuropsychiatry Clin Neurosci. 2020 Summer; 2019 Oct 17. PMID: 31619118.
Measurement and characterization of distinctive clinical phenotypes using the Frontotemporal Lobar Degeneration Module (FTLD-MOD).Gefen T, Teylan MA, Besser L, Pollner E, Moshkovich A, Weintraub S. Alzheimers Dement. 2020 Jun; 2020 May 13. PMID: 32400973.
Clinical and neuropsychological profile of patients with dementia and chronic traumatic encephalopathy.LoBue C, Schaffert J, Cullum CM, Peters ME, Didehbani N, Hart J, White CL. J Neurol Neurosurg Psychiatry. 2020 Jun; 2020 Apr 24. PMID: 32332103.
Non-memory cognitive symptom development in Alzheimer's disease.Blenkinsop A, van der Flier WM, Wolk D, Lehmann M, Howard R, Frost C, Barnes J. Eur J Neurol. 2020 Jun; 2020 Mar 29. PMID: 32078209.
Utility of spontaneous animal models of Alzheimer's disease in preclinical efficacy studies.Zeiss CJ. Cell Tissue Res. 2020 May; 2020 Apr 27. PMID: 32337614.
Amyloid: From Starch to Finish.Krystal HL, Ross DA, Mecca AP. Biol Psychiatry. 2020 May 1. PMID: 32299582.
Deep ensemble learning for Alzheimer's disease classification.An N, Ding H, Yang J, Au R, Ang TFA. J Biomed Inform. 2020 May; 2020 Mar 29. PMID: 32234546.
Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy.Gauthreaux K, Bonnett TA, Besser LM, Brenowitz WD, Teylan M, Mock C, Chen YC, Chan KCG, Keene CD, Zhou XH, Kukull WA. J Neuropathol Exp Neurol. 2020 May 1. PMID: 32186726.
The Effect of the APOE ε2ε4 Genotype on the Development of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) in Non-Latino Whites.Ren D, Lopez OL, Lingler JH, Conley Y. J Am Geriatr Soc. 2020 May; 2020 Feb 4. PMID: 32017008.
Informant Reporting in Mild Cognitive Impairment: Sources of Discrepancy on the Functional Activities Questionnaire.Hackett K, Mis R, Drabick DAG, Giovannetti T. J Int Neuropsychol Soc. 2020 May; 2020 Jan 22. PMID: 31964443.
Statin Use and Risk of Cognitive Decline in the ADNI Cohort.Kemp EC, Ebner MK, Ramanan S, Godek TA, Pugh EA, Bartlett HH, McDonald JW, Mecca MC, van Dyck CH, Mecca AP. Am J Geriatr Psychiatry. 2020 May; 2019 Nov 11. PMID: 31806426.
Subjective Memory Complaints in White and African American Participants.John SE, Evans SA, Hanfelt J, Loring DW, Goldstein FC. J Geriatr Psychiatry Neurol. 2020 May; 2019 Aug 13. PMID: 31409180.
Factor Consistency of Neuropsychological Test Battery Versions in the NACC Uniform Data Set.Culhane JE, Chan KCG, Teylan MA, Chen YC, Mock C, Gauthreaux K, Kukull WA. Alzheimer Dis Assoc Disord. 2020 Apr-Jun. PMID: 32218065.
Complex interactions underlie racial disparity in the risk of developing Alzheimer's disease dementia.Xiong C, Luo J, Coble D, Agboola F, Kukull W, Morris JC. Alzheimers Dement. 2020 Apr; 2020 Feb 17. PMID: 32067357.
Umbilical cord hypercoiling in two rhesus macaques (Macaca mulatta).Sarfaty AE, Zeiss CJ, Yekkala K, Wilson SR. J Med Primatol. 2020 Apr; 2019 Dec 26. PMID: 31879963.
Transverse myelitis following measles vaccination in a rhesus macaque (Macaca mulatta).Sarfaty AE, Fulbright RK, Compton SR, Asher JL, Zeiss CJ. J Med Primatol. 2020 Apr; 2019 Dec 2. PMID: 31789460.
Neuropsychiatric symptoms in cognitively normal older persons, and the association with Alzheimer's and non-Alzheimer's dementia.Liew TM. Alzheimers Res Ther. 2020 Mar 31; 2020 Mar 31. PMID: 32234066.
TREM2: Modulator of Lipid Metabolism in Microglia.Damisah EC, Rai A, Grutzendler J. Neuron. 2020 Mar 4. PMID: 32135085.
Distilling Heterogeneity of Mild Cognitive Impairment in the National Alzheimer Coordinating Center Database Using Latent Profile Analysis.Blanken AE, Jang JY, Ho JK, Edmonds EC, Han SD, Bangen KJ, Nation DA. JAMA Netw Open. 2020 Mar 2; 2020 Mar 2. PMID: 32142126.
The clinical promise of biomarkers of synapse damage or loss in Alzheimer's disease.Colom-Cadena M, Spires-Jones T, Zetterberg H, Blennow K, Caggiano A, DeKosky ST, Fillit H, Harrison JE, Schneider LS, Scheltens P, de Haan W, Grundman M, van Dyck CH, Izzo NJ, Catalano SM. Alzheimers Res Ther. 2020 Mar 2; 2020 Mar 2. PMID: 32122400.
Risk factors for earlier dementia onset in autopsy-confirmed Alzheimer's disease, mixed Alzheimer's with Lewy bodies, and pure Lewy body disease.Schaffert J, LoBue C, White CL 3rd, Wilmoth K, Didehbani N, Lacritz L, Nguyen T, Peters ME, Fields L, Li C, Cullum CM. Alzheimers Dement. 2020 Mar; 2020 Feb 11. PMID: 32043803.
Synthesis and Preclinical Evaluation of an (18)F-Labeled Synaptic Vesicle Glycoprotein 2A PET Imaging Probe: [(18)F]SynVesT-2.Cai Z, Li S, Zhang W, Pracitto R, Wu X, Baum E, Finnema SJ, Holden D, Toyonaga T, Lin SF, Lindemann M, Shirali A, Labaree DC, Ropchan J, Nabulsi N, Carson RE, Huang Y. ACS Chem Neurosci. 2020 Feb 19; 2020 Feb 4. PMID: 31961649.
Cognitively unimpaired adults' reactions to disclosure of amyloid PET scan results.Largent EA, Harkins K, van Dyck CH, Hachey S, Sankar P, Karlawish J. PLoS One. 2020; 2020 Feb 13. PMID: 32053667.
Cognitive trajectory in mild cognitive impairment due to primary age-related tauopathy.Teylan M, Mock C, Gauthreaux K, Chen YC, Chan KCG, Hassenstab J, Besser LM, Kukull WA, Crary JF. Brain. 2020 Feb 1. PMID: 31942622.
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models.Song JX, Malampati S, Zeng Y, Durairajan SSK, Yang CB, Tong BC, Iyaswamy A, Shang WB, Sreenivasmurthy SG, Zhu Z, Cheung KH, Lu JH, Tang C, Xu N, Li M. Aging Cell. 2020 Feb; 2019 Dec 19. PMID: 31858697.
History of traumatic brain injury interferes with accurate diagnosis of Alzheimer's dementia: a nation-wide case-control study.Pradeep T, Bray MJC, Arun S, Richey LN, Jahed S, Bryant BR, LoBue C, Lyketsos CG, Kim P, Peters ME. Int Rev Psychiatry. 2020 Feb; 2019 Nov 11. PMID: 31707905.
Distributed Patterns of Functional Connectivity Predict Working Memory Performance in Novel Healthy and Memory-impaired Individuals.Avery EW, Yoo K, Rosenberg MD, Greene AS, Gao S, Na DL, Scheinost D, Constable TR, Chun MM. J Cogn Neurosci. 2020 Feb; 2019 Oct 29. PMID: 31659926.
Gender role in sleep disturbances among older adults with traumatic brain injury.Ledger C, Karameh WK, Munoz DG, Fischer CE, Schweizer TA. Int Rev Psychiatry. 2020 Feb; 2019 Sep 23. PMID: 31544552.
Targeting Aggrephagy for the Treatment of Alzheimer's Disease.Malampati S, Song JX, Chun-Kit Tong B, Nalluri A, Yang CB, Wang Z, Gopalkrishnashetty Sreenivasmurthy S, Zhu Z, Liu J, Su C, Krishnamoorthi S, Iyaswamy A, Cheung KH, Lu JH, Li AM. Cells. 2020 Jan 28; 2020 Jan 28. PMID: 32012902.
Tracking Multimorbidity Changes in Diverse Racial/Ethnic Populations Over Time: Issues and Considerations.Quiñones AR, Allore HG, Botoseneanu A, Newsom JT, Nagel CL, Dorr DA. J Gerontol A Biol Sci Med Sci. 2020 Jan 20. PMID: 30721991.
Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31.Labonne JDJ, Driessen TM, Harris ME, Kong IK, Brakta S, Theisen J, Sangare M, Layman LC, Kim CH, Lim J, Kim HG. J Clin Med. 2020 Jan 19; 2020 Jan 19. PMID: 31963867.
PET imaging of mGluR5 in Alzheimer's disease.Mecca AP, McDonald JW, Michalak HR, Godek TA, Harris JE, Pugh EA, Kemp EC, Chen MK, Salardini A, Nabulsi NB, Lim K, Huang Y, Carson RE, Strittmatter SM, van Dyck CH. Alzheimers Res Ther. 2020 Jan 18; 2020 Jan 18. PMID: 31954399.
β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade.Zhang F, Gannon M, Chen Y, Yan S, Zhang S, Feng W, Tao J, Sha B, Liu Z, Saito T, Saido T, Keene CD, Jiao K, Roberson ED, Xu H, Wang Q. Sci Transl Med. 2020 Jan 15. PMID: 31941827.
GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.Hanson JE, Ma K, Elstrott J, Weber M, Saillet S, Khan AS, Simms J, Liu B, Kim TA, Yu GQ, Chen Y, Wang TM, Jiang Z, Liederer BM, Deshmukh G, Solanoy H, Chan C, Sellers BD, Volgraf M, Schwarz JB, Hackos DH, Weimer RM, Sheng M, Gill TM, Scearce-Levie K, Palop JJ. Cell Rep. 2020 Jan 14. PMID: 31940483.
Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex.Datta D, Leslie SN, Morozov YM, Duque A, Rakic P, van Dyck CH, Nairn AC, Arnsten AFT. J Neuroinflammation. 2020 Jan 6; 2020 Jan 6. PMID: 31906973.
The Contribution of Cerebral Vascular Neuropathology to Mild Stage of Alzheimer's Dementia Using the NACC Database.Liu Y, Chan DK, Crawford JD, Sachdev PS, Braidy N. Curr Alzheimer Res. 2020. PMID: 33583381.
Rectifying Attenuated Store-Operated Calcium Entry as a Therapeutic Approach for Alzheimer's Disease.Huang AS, Tong BCK, Wu AJ, Chen X, Sreenivasmurthy SG, Zhu Z, Liu J, Su C, Li M, Cheung KH. Curr Alzheimer Res. 2020. PMID: 33463469.
A Comparison of Neurocognitive Decline in Older Adults in Same-Sex and Opposite-Sex Relationships.Manca R, Venneri A. Curr Alzheimer Res. 2020. PMID: 33459235.
Revised Framingham Stroke Risk Profile: Association with Cognitive Status and MRI-Derived Volumetric Measures.Pelcher I, Puzo C, Tripodis Y, Aparicio HJ, Steinberg EG, Phelps A, Martin B, Palmisano JN, Vassey E, Lindbergh C, McKee AC, Stein TD, Killiany RJ, Au R, Kowall NW, Stern RA, Mez J, Alosco ML. J Alzheimers Dis. 2020. PMID: 33164933.
Characterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans.Mezlini AM, Magdamo C, Merrill E, Chibnik LB, Blacker DL, Hyman BT, Das S. J Alzheimers Dis. 2020. PMID: 33016904.
Evidence for the Utility of Actuarial Neuropsychological Criteria Across the Continuum of Normal Aging, Mild Cognitive Impairment, and Dementia.Graves LV, Edmonds EC, Thomas KR, Weigand AJ, Cooper S, Bondi MW. J Alzheimers Dis. 2020. PMID: 32986674.
Ethnoracial Differences in Lewy Body Diseases with Cognitive Impairment.Kurasz AM, Smith GE, McFarland MG, Armstrong MJ. J Alzheimers Dis. 2020. PMID: 32804137.
Neuropsychiatric Inventory-Assessed Nighttime Behavior Accompanies, but Does Not Precede, Progressive Cognitive Decline Independent of Alzheimer's Disease Histopathology.Atayde AL, Fischer CE, Schweizer TA, Munoz DG. J Alzheimers Dis. 2020. PMID: 32116249.
Association of Hypercholesterolemia with Alzheimer's Disease Pathology and Cerebral Amyloid Angiopathy.Xu C, Apostolova LG, Oblak AL, Gao S. J Alzheimers Dis. 2020. PMID: 31929164.
NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models.Iyaswamy A, Krishnamoorthi SK, Song JX, Yang CB, Kaliyamoorthy V, Zhang H, Sreenivasmurthy SG, Malampati S, Wang ZY, Zhu Z, Tong BC, Cheung KH, Lu JH, Durairajan SSK, Li M. J Food Drug Anal. 2020 Jan; 2019 Oct 8. PMID: 31883601.
Mitochondrial Calcium Signaling as a Therapeutic Target for Alzheimer's Disease.Wu AJ, Tong BC, Huang AS, Li M, Cheung KH. Curr Alzheimer Res. 2020. PMID: 31820698.
Subjective Memory Complaints Are an Important Surrogate for Objective Cognitive Performance in African Americans.Boggess MB, Barber JM, Jicha GA, Caban-Holt A. Alzheimer Dis Assoc Disord. 2020 Jan-Mar. PMID: 31633556.
Interpreting in vivo calcium signals from neuronal cell bodies, axons, and dendrites: a review.Ali F, Kwan AC. Neurophotonics. 2020 Jan; 2019 Jul 30. PMID: 31372367.
Comorbid conditions and emergency department treat and release utilization in multimorbid persons with cognitive impairment.MacNeil-Vroomen JL, Nagurney JM, Allore HG. Am J Emerg Med. 2020 Jan; 2019 Jul 16. PMID: 31337598.

2019

Alzheimer's-like pathology in aging rhesus macaques: Unique opportunity to study the etiology and treatment of Alzheimer's disease.Arnsten AFT, Datta D, Leslie S, Yang ST, Wang M, Nairn AC. Proc Natl Acad Sci U S A. 2019 Dec 26; 2019 Dec 23. PMID: 31871209.
Menagerie: A text-mining tool to support animal-human translation in neurodegeneration research.Zeiss CJ, Shin D, Vander Wyk B, Beck AP, Zatz N, Sneiderman CA, Kilicoglu H. PLoS One. 2019; 2019 Dec 17. PMID: 31846471.
Magnetic resonance imaging brain atrophy assessment in primary age-related tauopathy (PART).Quintas-Neves M, Teylan MA, Besser L, Soares-Fernandes J, Mock CN, Kukull WA, Crary JF, Oliveira TG. Acta Neuropathol Commun. 2019 Dec 9; 2019 Dec 9. PMID: 31818331.
Nonlinear Z-score modeling for improved detection of cognitive abnormality.Kornak J, Fields J, Kremers W, Farmer S, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Besser L, Appleby B, Bordelon Y, Bove J, Brannelly P, Caso C, Coppola G, Dever R, Dheel C, Dickerson B, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fishman A, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant IM, Grossman M, Haley D, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kraft R, Kramer J, Kukull W, Lapid M, Litvan I, Ljubenkov P, Lucente D, Lungu C, Mackenzie I, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez M, Miller B, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Roberson ED, Rogalski-Miller E, Sengdy P, Shaw L, Staffaroni AM, Sutherland M, Syrjanen J, Tartaglia C, Tatton N, Taylor J, Toga A, Trojanowski J, Wang P, Wong B, Wszolek Z, Boeve B, Boxer A, Rosen H. Alzheimers Dement (Amst). 2019 Dec; 2019 Dec 5. PMID: 31872042.
Association between enrollment factors and incident cognitive impairment in Blacks and Whites: Data from the Alzheimer's Disease Center.Gleason CE, Norton D, Zuelsdorff M, Benton SF, Wyman MF, Nystrom N, Lambrou N, Salazar H, Koscik RL, Jonaitis E, Carter F, Harris B, Gee A, Chin N, Ketchum F, Johnson SC, Edwards DF, Carlsson CM, Kukull W, Asthana S. Alzheimers Dement. 2019 Dec; 2019 Oct 7. PMID: 31601516.
Braak neurofibrillary tangle staging prediction from in vivo MRI metrics.Dallaire-Théroux C, Beheshti I, Potvin O, Dieumegarde L, Saikali S, Duchesne S. Alzheimers Dement (Amst). 2019 Dec; 2019 Sep 4. PMID: 31517022.
Trajectories of neuropsychiatric symptoms over time in healthy volunteers and risk of MCI and dementia.Leoutsakos JS, Wise EA, Lyketsos CG, Smith GS. Int J Geriatr Psychiatry. 2019 Dec; 2019 Sep 2. PMID: 31452260.
A 4-Item Case-Finding Tool to Detect Dementia in Older Persons.Liew TM. J Am Med Dir Assoc. 2019 Dec; 2019 Aug 7. PMID: 31399363.
In Vivo Synaptic Density Imaging with (11)C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease.Toyonaga T, Smith LM, Finnema SJ, Gallezot JD, Naganawa M, Bini J, Mulnix T, Cai Z, Ropchan J, Huang Y, Strittmatter SM, Carson RE. J Nucl Med. 2019 Dec; 2019 May 17. PMID: 31101744.
Time course of neuropsychiatric symptoms and cognitive diagnosis in National Alzheimer's Coordinating Centers volunteers.Wise EA, Rosenberg PB, Lyketsos CG, Leoutsakos JM. Alzheimers Dement (Amst). 2019 Dec; 2019 Apr 18. PMID: 31024987.
Sociodemographic Factors and Characteristics of Caregivers as Determinants of Skilled Nursing Facility Admissions When Modeled Jointly With Functional Limitations.Jørgensen TSH, Allore H, MacNeil Vroomen JL, Wyk BV, Agogo GO. J Am Med Dir Assoc. 2019 Dec; 2019 Mar 20. PMID: 30902676.
Transformation model estimation of survival under dependent truncation and independent censoring.Chiou SH, Austin MD, Qian J, Betensky RA. Stat Methods Med Res. 2019 Dec; 2018 Dec 13. PMID: 30543153.
Institutionalization risk and costs associated with agitation in Alzheimer's disease.Cloutier M, Gauthier-Loiselle M, Gagnon-Sanschagrin P, Guerin A, Hartry A, Baker RA, Duffy R, Gwin K, Sanon Aigbogun M. Alzheimers Dement (N Y). 2019; 2019 Nov 23. PMID: 31799369.
Concentration-dependent Toxicity after Subcutaneous Administration of Meloxicam to C57BL/6N Mice (Mus musculus).Sarfaty AE, Zeiss CJ, Willis AD, Harris JM, Smith PC. J Am Assoc Lab Anim Sci. 2019 Nov 1; 2019 Sep 20. PMID: 31540585.
Group differences in normal neuropsychological test performance for older non-Hispanic White and Black/African American adults.Werry AE, Daniel M, Bergström B. Neuropsychology. 2019 Nov; 2019 Jul 25. PMID: 31343234.
Cognitive and functional progression of dementia in two longitudinal studies.Wang Y, Haaksma ML, Ramakers IHGB, Verhey FRJ, van de Flier WM, Scheltens P, van Maurik I, Olde Rikkert MGM, Leoutsakos JS, Melis RJF. Int J Geriatr Psychiatry. 2019 Nov; 2019 Jul 26. PMID: 31318090.
Alzheimer's disease progression and risk factors: A standardized comparison between six large data sets.Evans S, McRae-McKee K, Hadjichrysanthou C, Wong MM, Ames D, Lopez O, de Wolf F, Anderson RM. Alzheimers Dement (N Y). 2019; 2019 Oct 3. PMID: 31650008.
Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis.Roczniak-Ferguson A, Ferguson SM. Life Sci Alliance. 2019 Oct; 2019 Sep 16. PMID: 31527135.
Assessing cost-effectiveness of early intervention in Alzheimer's disease: An open-source modeling framework.Green C, Handels R, Gustavsson A, Wimo A, Winblad B, Sköldunger A, Jönsson L. Alzheimers Dement. 2019 Oct; 2019 Aug 8. PMID: 31402324.
Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial.van Dyck CH, Nygaard HB, Chen K, Donohue MC, Raman R, Rissman RA, Brewer JB, Koeppe RA, Chow TW, Rafii MS, Gessert D, Choi J, Turner RS, Kaye JA, Gale SA, Reiman EM, Aisen PS, Strittmatter SM. JAMA Neurol. 2019 Oct 1. PMID: 31329216.
Enhanced Population Coding for Rewarded Choices in the Medial Frontal Cortex of the Mouse.Siniscalchi MJ, Wang H, Kwan AC. Cereb Cortex. 2019 Sep 13. PMID: 30615132.
The Multilingual Naming Test (MINT) as a Measure of Picture Naming Ability in Alzheimer's Disease.Stasenko A, Jacobs DM, Salmon DP, Gollan TH. J Int Neuropsychol Soc. 2019 Sep; 2019 Jun 28. PMID: 31248465.
Cognitive heterogeneity in probable Alzheimer disease: Clinical and neuropathologic features.Qiu Y, Jacobs DM, Messer K, Salmon DP, Feldman HH. Neurology. 2019 Aug 20; 2019 Jul 18. PMID: 31320469.
Whole-Exome Sequencing of an Exceptional Longevity Cohort.Nygaard HB, Erson-Omay EZ, Wu X, Kent BA, Bernales CQ, Evans DM, Farrer MJ, Vilariño-Güell C, Strittmatter SM. J Gerontol A Biol Sci Med Sci. 2019 Aug 16. PMID: 29750252.
Depression, subjective cognitive decline, and the risk of neurocognitive disorders.Liew TM. Alzheimers Res Ther. 2019 Aug 9; 2019 Aug 9. PMID: 31399132.
Doxorubicin-Induced Cardiotoxicity in Collaborative Cross (CC) Mice Recapitulates Individual Cardiotoxicity in Humans.Zeiss CJ, Gatti DM, Toro-Salazar O, Davis C, Lutz CM, Spinale F, Stearns T, Furtado MB, Churchill GA. G3 (Bethesda). 2019 Aug 8; 2019 Aug 8. PMID: 31263061.
Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials.Andrews JS, Desai U, Kirson NY, Zichlin ML, Ball DE, Matthews BR. Alzheimers Dement (N Y). 2019; 2019 Aug 2. PMID: 31417957.
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, Lunetta KL. Aging Cell. 2019 Aug; 2019 May 29. PMID: 31144443.
Developing a Brief Neuropsychological Battery for Early Diagnosis of Cognitive Impairment.Liew TM. J Am Med Dir Assoc. 2019 Aug; 2019 Apr 13. PMID: 30992186.
Symptom Clusters of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Their Comparative Risks of Dementia: A Cohort Study of 8530 Older Persons.Liew TM. J Am Med Dir Assoc. 2019 Aug; 2019 Mar 26. PMID: 30926409.
The Optimal Short Version of Montreal Cognitive Assessment in Diagnosing Mild Cognitive Impairment and Dementia.Liew TM. J Am Med Dir Assoc. 2019 Aug; 2019 Mar 23. PMID: 30910550.
The Roles of Apathy and Depression in Predicting Alzheimer Disease: A Longitudinal Analysis in Older Adults With Mild Cognitive Impairment.Ruthirakuhan M, Herrmann N, Vieira D, Gallagher D, Lanctôt KL. Am J Geriatr Psychiatry. 2019 Aug; 2019 Feb 7. PMID: 30910421.
Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Data Set.Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML. Alzheimers Res Ther. 2019 Jul 27; 2019 Jul 27. PMID: 31351489.
Chronic Conditions, Medically Supportive Care Partners, And Functional Disability Among Cognitively Impaired Adults.Van Ness PH, MacNeil Vroomen J, Leo-Summers L, Vander Wyk B, Allore HG. Innov Aging. 2019 May; 2019 Jul 2. PMID: 31286072.
The impact of cardiovascular risk factors on cognition in Hispanics and non-Hispanic whites.Stickel A, McKinnon A, Ruiz J, Grilli MD, Ryan L. Learn Mem. 2019 Jul; 2019 Jun 17. PMID: 31209118.
Association of Early-Onset Alzheimer Disease With Elevated Low-Density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB.Wingo TS, Cutler DJ, Wingo AP, Le NA, Rabinovici GD, Miller BL, Lah JJ, Levey AI. JAMA Neurol. 2019 Jul 1. PMID: 31135820.
Discriminative Ability of Montreal Cognitive Assessment Subtests and Items in Racial and Ethnic Minority Groups.Milani SA, Marsiske M, Striley CW. Alzheimer Dis Assoc Disord. 2019 Jul-Sep. PMID: 31058685.
Clinical diagnoses among individuals with primary age-related tauopathy versus Alzheimer's neuropathology.Teylan M, Besser LM, Crary JF, Mock C, Gauthreaux K, Thomas NM, Chen YC, Kukull WA. Lab Invest. 2019 Jul; 2019 Feb 1. PMID: 30710118.
Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms.Keine D, Zelek M, Walker JQ, Sabbagh MN. Neurol Ther. 2019 Jun; 2019 Mar 21. PMID: 30900186.
Risk of dementia and mild cognitive impairment among older adults in same-sex relationships.Perales-Puchalt J, Gauthreaux K, Flatt J, Teylan MA, Resendez J, Kukull WA, Chan KCG, Burns J, Vidoni ED. Int J Geriatr Psychiatry. 2019 Jun; 2019 Apr 22. PMID: 30864178.
Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer's Disease Pathology.Stoiljkovic M, Kelley C, Stutz B, Horvath TL, Hajós M. Cereb Cortex. 2019 Jun 1. PMID: 29920597.
Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia.Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML. Alzheimers Dement. 2019 May; 2019 Mar 7. PMID: 30852157.
Systematic and standardized comparison of reported amyloid-β receptors for sufficiency, affinity, and Alzheimer's disease relevance.Smith LM, Kostylev MA, Lee S, Strittmatter SM. J Biol Chem. 2019 Apr 12; 2019 Feb 20. PMID: 30787106.
Randomized Trial of Verubecestat for Prodromal Alzheimer's Disease.Egan MF, Kost J, Voss T, Mukai Y, Aisen PS, Cummings JL, Tariot PN, Vellas B, van Dyck CH, Boada M, Zhang Y, Li W, Furtek C, Mahoney E, Harper Mozley L, Mo Y, Sur C, Michelson D. N Engl J Med. 2019 Apr 11. PMID: 30970186.
Confidence Intervals for the Area Under the Receiver Operating Characteristic Curve in the Presence of Ignorable Missing Data.Cho H, Matthews GJ, Harel O. Int Stat Rev. 2019 Apr; 2018 Aug 9. PMID: 31007356.
Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers.Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR, Ances BM, Berman SB, Brosch JR, Galasko D, Gauthier S, Lah JJ, Masellis M, van Dyck CH, Mintun MA, Klein G, Ristic S, Cairns NJ, Marcus DS, Xiong C, Holtzman DM, Raichle ME, Morris JC, Bateman RJ, Benzinger TLS. Brain. 2019 Apr 1. PMID: 30753379.
Cholinesterase Inhibitors May Not Benefit Mild Cognitive Impairment and Mild Alzheimer Disease Dementia.Han JY, Besser LM, Xiong C, Kukull WA, Morris JC. Alzheimer Dis Assoc Disord. 2019 Apr-Jun. PMID: 30633043.
Neuronal lysosomes.Ferguson SM. Neurosci Lett. 2019 Apr 1; 2018 Apr 4. PMID: 29626653.
Safety and efficacy of active and passive immunotherapy in mild-to-moderate Alzheimer's disease: A systematic review and network meta-analysis.Foroutan N, Hopkins RB, Tarride JE, Florez ID, Levine M. Clin Invest Med. 2019 Mar 23; 2019 Mar 23. PMID: 30904037.
Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model.Merlini M, Rafalski VA, Rios Coronado PE, Gill TM, Ellisman M, Muthukumar G, Subramanian KS, Ryu JK, Syme CA, Davalos D, Seeley WW, Mucke L, Nelson RB, Akassoglou K. Neuron. 2019 Mar 20; 2019 Feb 5. PMID: 30737131.
An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease.Mäkeläinen S, Gòdia M, Hellsand M, Viluma A, Hahn D, Makdoumi K, Zeiss CJ, Mellersh C, Ricketts SL, Narfström K, Hallböök F, Ekesten B, Andersson G, Bergström TF. PLoS Genet. 2019 Mar; 2019 Mar 19. PMID: 30889179.
Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss.Lee S, Salazar SV, Cox TO, Strittmatter SM. J Neurosci. 2019 Mar 6; 2019 Jan 9. PMID: 30626696.
Anti-PrP(C) antibody rescues cognition and synapses in transgenic alzheimer mice.Cox TO, Gunther EC, Brody AH, Chiasseu MT, Stoner A, Smith LM, Haas LT, Hammersley J, Rees G, Dosanjh B, Groves M, Gardener M, Dobson C, Vaughan T, Chessell I, Billinton A, Strittmatter SM. Ann Clin Transl Neurol. 2019 Mar; 2019 Feb 27. PMID: 30911579.
Differences in Cognitive Impairment in Primary Age-Related Tauopathy Versus Alzheimer Disease.Besser LM, Mock C, Teylan MA, Hassenstab J, Kukull WA, Crary JF. J Neuropathol Exp Neurol. 2019 Mar 1. PMID: 30715383.
Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities.Burke SL, Hu T, Fava NM, Li T, Rodriguez MJ, Schuldiner KL, Burgess A, Laird A. J Women Aging. 2019 Mar-Apr; 2018 Jan 10. PMID: 29319430.
Predictors of finance management in dementia: managing bills and taxes matters.Giebel CM, Flanagan E, Sutcliffe C. Int Psychogeriatr. 2019 Feb; 2018 Aug 13. PMID: 30099977.
Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists.Gunther EC, Smith LM, Kostylev MA, Cox TO, Kaufman AC, Lee S, Folta-Stogniew E, Maynard GD, Um JW, Stagi M, Heiss JK, Stoner A, Noble GP, Takahashi H, Haas LT, Schneekloth JS, Merkel J, Teran C, Naderi ZK, Supattapone S, Strittmatter SM. Cell Rep. 2019 Jan 29. PMID: 30699361.
Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and Loss.Salazar SV, Cox TO, Lee S, Brody AH, Chyung AS, Haas LT, Strittmatter SM. J Neurosci. 2019 Jan 23; 2018 Dec 5. PMID: 30518596.
Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study.Oh G, Abner EL, Fardo DW, Freeman PR, Moga DC. PLoS One. 2019; 2019 Jan 11. PMID: 30633773.
Rescue of Transgenic Alzheimer's Pathophysiology by Polymeric Cellular Prion Protein Antagonists.Gunther EC, Smith LM, Kostylev MA, Cox TO, Kaufman AC, Lee S, Folta-Stogniew E, Maynard GD, Um JW, Stagi M, Heiss JK, Stoner A, Noble GP, Takahashi H, Haas LT, Schneekloth JS, Merkel J, Teran C, Naderi ZK, Supattapone S, Strittmatter SM. Cell Rep. 2019 Jan 2. PMID: 30605671.
APOE ɛ4/ɛ4 Is Associated with Aberrant Motor Behavior Through Both Lewy Body and Cerebral Amyloid Angiopathy Pathology in High Alzheimer's Disease Pathological Load.Garcia-Segura ME, Fischer CE, Schweizer TA, Munoz DG. J Alzheimers Dis. 2019. PMID: 31744003.
Parvalbumin-Positive Neuron Loss and Amyloid-β Deposits in the Frontal Cortex of Alzheimer's Disease-Related Mice.Ali F, Baringer SL, Neal A, Choi EY, Kwan AC. J Alzheimers Dis. 2019. PMID: 31743995.
Behavioral versus Biological Definitions of Dementia Symptoms: Recognizing that Worthwhile Interventions already Exist.Brent RJ. OBM Geriat. 2019; 2019 Oct 10. PMID: 31737867.
AD molecular: Molecular imaging of Alzheimer's disease: PET imaging of neurotransmitter systems.Mecca AP. Prog Mol Biol Transl Sci. 2019; 2019 May 23. PMID: 31481161.
APOEɛ4 Gene Dose and Sex Effects on Alzheimer's Disease MRI Biomarkers in Older Adults with Mild Cognitive Impairment.Hobel Z, Isenberg AL, Raghupathy D, Mack W, Pa J. J Alzheimers Dis. 2019. PMID: 31424388.
The Pathology of Rapid Cognitive Decline in Clinically Diagnosed Alzheimer's Disease.Nance C, Ritter A, Miller JB, Lapin B, Banks SJ. J Alzheimers Dis. 2019. PMID: 31306127.
Associations between Comorbid TDP-43, Lewy Body Pathology, and Neuropsychiatric Symptoms in Alzheimer's Disease.Bayram E, Shan G, Cummings JL. J Alzheimers Dis. 2019. PMID: 31127776.
Genetic Sample Provision Among National Alzheimer's Coordinating Center Participants.Bardach SH, Jicha GA, Karanth S, Zhang X, Abner EL. J Alzheimers Dis. 2019. PMID: 30958359.
Heterogeneity of Informant-Reported Functional Performance in Mild Cognitive Impairment: A Latent Profile Analysis of the Functional Activities Questionnaire.Mis R, Devlin K, Drabick D, Giovannetti T. J Alzheimers Dis. 2019. PMID: 30909219.
Abnormal Sleep Behaviours Across the Spectrum of Alzheimer's Disease Severity: Influence of APOE Genotypes and Lewy Bodies.Koo KYG, Schweizer TA, Fischer CE, Munoz DG. Curr Alzheimer Res. 2019. PMID: 30605058.
cAMP regulation of protein phosphatases PP1 and PP2A in brain.Leslie SN, Nairn AC. Biochim Biophys Acta Mol Cell Res. 2019 Jan; 2018 Sep 18. PMID: 30401536.

2018

Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsing.Rindflesch TC, Blake CL, Cairelli MJ, Fiszman M, Zeiss CJ, Kilicoglu H. J Biomed Semantics. 2018 Dec 27; 2018 Dec 27. PMID: 30587224.
Pathology Study Design, Conduct, and Reporting to Achieve Rigor and Reproducibility in Translational Research Using Animal Models.Everitt JI, Treuting PM, Scudamore C, Sellers R, Turner PV, Ward JM, Zeiss CJ. ILAR J. 2018 Dec 1. PMID: 30624739.
Mild cognitive impairment: associations with sleep disturbance, apolipoprotein e4, and sleep medications.Burke SL, Hu T, Spadola CE, Li T, Naseh M, Burgess A, Cadet T. Sleep Med. 2018 Dec; 2018 Sep 20. PMID: 30359892.
Effects of Normative Adjustments to the Montreal Cognitive Assessment.Pugh EA, Kemp EC, van Dyck CH, Mecca AP, Sharp ES. Am J Geriatr Psychiatry. 2018 Dec; 2018 Sep 21. PMID: 30314940.
Performance validity in older adults: Observed versus predicted false positive rates in relation to number of tests administered.Davis JJ. J Clin Exp Neuropsychol. 2018 Dec; 2018 May 20. PMID: 29779432.
Toward Prevention of Mild Cognitive Impairment in Older Adults With Depression: An Observational Study of Potentially Modifiable Risk Factors.Gallagher D, Kiss A, Lanctot KL, Herrmann N. J Clin Psychiatry. 2018 Nov 27; 2018 Nov 27. PMID: 30549490.
Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly.Lee S, Zhou X, Gao Y, Vardarajan B, Reyes-Dumeyer D, Rajan KB, Wilson RS, Evans DA, Besser LM, Kukull WA, Bennett DA, Brickman AM, Schupf N, Mayeux R, Barral S. PLoS One. 2018; 2018 Nov 21. PMID: 30462667.
Liquid and Hydrogel Phases of PrP(C) Linked to Conformation Shifts and Triggered by Alzheimer's Amyloid-β Oligomers.Kostylev MA, Tuttle MD, Lee S, Klein LE, Takahashi H, Cox TO, Gunther EC, Zilm KW, Strittmatter SM. Mol Cell. 2018 Nov 1; 2018 Oct 25. PMID: 30401430.
Identification of a novel microRNA profile in pediatric patients with cancer treated with anthracycline chemotherapy.Oatmen KE, Toro-Salazar OH, Hauser K, Zellars KN, Mason KC, Hor K, Gillan E, Zeiss CJ, Gatti DM, Spinale FG. Am J Physiol Heart Circ Physiol. 2018 Nov 1; 2018 Aug 24. PMID: 30141982.
Calcium signaling in Alzheimer's disease & therapies.Tong BC, Wu AJ, Li M, Cheung KH. Biochim Biophys Acta Mol Cell Res. 2018 Nov; 2018 Jul 29. PMID: 30059692.
Neurophysiological signals as predictive translational biomarkers for Alzheimer's disease treatment: effects of donepezil on neuronal network oscillations in TgF344-AD rats.Stoiljkovic M, Kelley C, Horvath TL, Hajós M. Alzheimers Res Ther. 2018 Oct 10; 2018 Oct 10. PMID: 30301466.
Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia?Crum J, Wilson J, Sabbagh M. Alzheimers Res Ther. 2018 Oct 2; 2018 Oct 2. PMID: 30285877.
Acute Abdominal Distension Due to Disseminated Peritoneal Neoplasia in a Rhesus Macaque (Macaca mulatta).Asher JL, Barnett GJ, Zeiss CJ. Comp Med. 2018 Oct 1; 2018 Aug 23. PMID: 30139414.
Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging.Chen MK, Mecca AP, Naganawa M, Finnema SJ, Toyonaga T, Lin SF, Najafzadeh S, Ropchan J, Lu Y, McDonald JW, Michalak HR, Nabulsi NB, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. JAMA Neurol. 2018 Oct 1. PMID: 30014145.
Guanfacine treatment for prefrontal cognitive dysfunction in older participants: a randomized clinical trial.Barcelos NM, Van Ness PH, Wagner AF, MacAvoy MG, Mecca AP, Anderson GM, Trentalange M, Hawkins KA, Sano M, Arnsten AFT, van Dyck CH. Neurobiol Aging. 2018 Oct; 2018 May 31. PMID: 30007160.
Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout.Agogo GO, Ramsey CM, Gnjidic D, Moga DC, Allore H. Int Psychogeriatr. 2018 Oct; 2018 Apr 18. PMID: 29667565.
The Impact of Dementia Diagnosis on Patterns of Potentially Inappropriate Medication Use Among Older Adults.Gnjidic D, Agogo GO, Ramsey CM, Moga DC, Allore H. J Gerontol A Biol Sci Med Sci. 2018 Sep 11. PMID: 29684111.
WDR41 supports lysosomal response to changes in amino acid availability.Amick J, Tharkeshwar AK, Amaya C, Ferguson SM. Mol Biol Cell. 2018 Sep 1; 2018 Jul 11. PMID: 29995611.
Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center.Hanfelt JJ, Peng L, Goldstein FC, Lah JJ. Neurobiol Dis. 2018 Sep; 2018 Jun 1. PMID: 29859866.
Case-control studies of gene-environment interactions. When a case might not be the case.Lobach I, Sampson J, Alekseyenko A, Lobach S, Zhang L. PLoS One. 2018; 2018 Aug 22. PMID: 30133451.
GATOR1-dependent recruitment of FLCN-FNIP to lysosomes coordinates Rag GTPase heterodimer nucleotide status in response to amino acids.Meng J, Ferguson SM. J Cell Biol. 2018 Aug 6; 2018 May 30. PMID: 29848618.
Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults.Burke SL, Cadet T, Maddux M. J Natl Med Assoc. 2018 Aug; 2017 Jul 18. PMID: 30126555.
Depression and Risk of Alzheimer Dementia: A Longitudinal Analysis to Determine Predictors of Increased Risk among Older Adults with Depression.Gallagher D, Kiss A, Lanctot K, Herrmann N. Am J Geriatr Psychiatry. 2018 Aug; 2018 May 9. PMID: 29960668.
Cognitive and functional progression in Alzheimer disease: A prediction model of latent classes.Haaksma ML, Calderón-Larrañaga A, Olde Rikkert MGM, Melis RJF, Leoutsakos JS. Int J Geriatr Psychiatry. 2018 Aug; 2018 May 15. PMID: 29761569.
Axonal transport and maturation of lysosomes.Ferguson SM. Curr Opin Neurobiol. 2018 Aug; 2018 Mar 9. PMID: 29529416.
Psychosis in "Cognitively Asymptomatic" Elderly Subjects is Associated With Neuritic Plaque Load, Not Neurofibrillary Tangles.Kim J, Schweizer TA, Fischer CE, Munoz DG. Alzheimer Dis Assoc Disord. 2018 Jul-Sep. PMID: 29553944.
Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks.Wang T, Qiu RG, Yu M. Sci Rep. 2018 Jun 15; 2018 Jun 15. PMID: 29907747.
The complex relationship between TFEB transcription factor phosphorylation and subcellular localization.Puertollano R, Ferguson SM, Brugarolas J, Ballabio A. EMBO J. 2018 Jun 1; 2018 May 15. PMID: 29764979.
ABBY: A phase 2 randomized trial of crenezumab in mild to moderate Alzheimer disease.Cummings JL, Cohen S, van Dyck CH, Brody M, Curtis C, Cho W, Ward M, Friesenhahn M, Rabe C, Brunstein F, Quartino A, Honigberg LA, Fuji RN, Clayton D, Mortensen D, Ho C, Paul R. Neurology. 2018 May 22; 2018 Apr 25. PMID: 29695589.
Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain.Hill RA, Li AM, Grutzendler J. Nat Neurosci. 2018 May; 2018 Mar 19. PMID: 29556031.
Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease.Schaffert J, LoBue C, White CL, Chiang HS, Didehbani N, Lacritz L, Rossetti H, Dieppa M, Hart J, Cullum CM. Neuropsychology. 2018 May; 2018 Feb 1. PMID: 29389151.
Surfactant protein C dampens inflammation by decreasing JAK/STAT activation during lung repair.Jin H, Ciechanowicz AK, Kaplan AR, Wang L, Zhang PX, Lu YC, Tobin RE, Tobin BA, Cohn L, Zeiss CJ, Lee PJ, Bruscia EM, Krause DS. Am J Physiol Lung Cell Mol Physiol. 2018 May 1; 2018 Jan 18. PMID: 29345196.
DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia.Tse KH, Cheng A, Ma F, Herrup K. Alzheimers Dement. 2018 May; 2018 Jan 9. PMID: 29328926.
The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology.Paspalas CD, Carlyle BC, Leslie S, Preuss TM, Crimins JL, Huttner AJ, van Dyck CH, Rosene DL, Nairn AC, Arnsten AFT. Alzheimers Dement. 2018 May; 2017 Dec 11. PMID: 29241829.
The Impact of Latino Values and Cultural Beliefs on Brain Donation: Results of a Pilot Study to Develop Culturally Appropriate Materials and Methods to Increase Rates of Brain Donation in this Under-Studied Patient Group.Bilbrey AC, Humber MB, Plowey ED, Garcia I, Chennapragada L, Desai K, Rosen A, Askari N, Gallagher-Thompson D. Clin Gerontol. 2018 May-Jun; 2017 Dec 11. PMID: 29227743.
Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration.Sekine Y, Lin-Moore A, Chenette DM, Wang X, Jiang Z, Cafferty WB, Hammarlund M, Strittmatter SM. Cell Rep. 2018 Apr 10. PMID: 29642001.
The Tyrosine Phosphatase STEP Is Involved in Age-Related Memory Decline.Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn AC, Norris CM, Ferland G, Bézard E, Gaudreau P, Lombroso PJ, Brouillette J. Curr Biol. 2018 Apr 2; 2018 Mar 22. PMID: 29576474.
Diabetes, Heart Disease, and Dementia: National Estimates of Functional Disability Trajectories.MacNeil Vroomen JL, Han L, Monin JK, Lipska KJ, Allore HG. J Am Geriatr Soc. 2018 Apr; 2018 Mar 9. PMID: 29521414.
The MoCA-Memory Index Score: An Efficient Alternative to Paragraph Recall for the Detection of Amnestic Mild Cognitive Impairment.Kaur A, Edland SD, Peavy GM. Alzheimer Dis Assoc Disord. 2018 Apr-Jun. PMID: 29319601.
Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment.Wilmoth K, LoBue C, Clem MA, Reddy R, Hynan LS, Didehbani N, Bell K, Womack KB, Hart J Jr, Batjer H, Cullum CM. Clin Neuropsychol. 2018 Apr; 2017 Oct 9. PMID: 28988512.
Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay.Nguyen AD, Nguyen TA, Zhang J, Devireddy S, Zhou P, Karydas AM, Xu X, Miller BL, Rigo F, Ferguson SM, Huang EJ, Walther TC, Farese RV Jr. Proc Natl Acad Sci U S A. 2018 Mar 20; 2018 Mar 6. PMID: 29511098.
Organelles in metabolism and stress responses.Ferguson SM, Henne WM. Mol Biol Cell. 2018 Mar 15. PMID: 29535175.
Disease-modifying benefit of Fyn blockade persists after washout in mouse Alzheimer's model.Smith LM, Zhu R, Strittmatter SM. Neuropharmacology. 2018 Mar 1; 2017 Nov 27. PMID: 29191754.
Emerging Mechanisms in Alzheimer's Disease and Their Therapeutic Implications.Strittmatter SM. Biol Psychiatry. 2018 Feb 15. PMID: 29331211.
Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging.Condello C, Yuan P, Grutzendler J. Biol Psychiatry. 2018 Feb 15; 2017 Oct 14. PMID: 29169609.
Anti-Amyloid-β Monoclonal Antibodies for Alzheimer's Disease: Pitfalls and Promise.van Dyck CH. Biol Psychiatry. 2018 Feb 15; 2017 Aug 24. PMID: 28967385.
The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer's disease.de Leon MJ, Pirraglia E, Osorio RS, Glodzik L, Saint-Louis L, Kim HJ, Fortea J, Fossati S, Laska E, Siegel C, Butler T, Li Y, Rusinek H, Zetterberg H, Blennow K. PLoS One. 2018; 2018 Feb 7. PMID: 29415068.
Making brain proteomics true to type.Wilson RS, Nairn AC. Nat Biotechnol. 2018 Feb 6. PMID: 29406511.
Cutaneous Toxicity in a Laboratory Beagle (Canis lupus familiaris) after Chronic Administration of Doxorubicin Hydrochloride.Guerriero KA, Wilson SR, Boutagy NE, Liu C, Sinusas AJ, Zeiss CJ. Comp Med. 2018 Feb 1. PMID: 29460722.
The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial.Scherer RW, Drye L, Mintzer J, Lanctôt K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH. Trials. 2018 Jan 18; 2018 Jan 18. PMID: 29347996.
The Paradoxical Impact of Companionship on the Mental Health of Older African American Men.Mitchell JA, Cadet T, Burke S, Williams ED, Alvarez D. J Gerontol B Psychol Sci Soc Sci. 2018 Jan 11. PMID: 28977531.
The Association Between Body Mass Index, and Cognitive, Functional, and Behavioral Declines for Incident Dementia.Michaud TL, Siahpush M, Farazi PA, Kim J, Yu F, Su D, Murman DL. J Alzheimers Dis. 2018. PMID: 30412484.
Traumatic Brain Injury and Age of Onset of Dementia with Lewy Bodies.Nguyen TP, Schaffert J, LoBue C, Womack KB, Hart J, Cullum CM. J Alzheimers Dis. 2018. PMID: 30320582.
Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies.Hadjichrysanthou C, McRae-McKee K, Evans S, de Wolf F, Anderson RM. J Alzheimers Dis. 2018. PMID: 30320573.
Cognitive Therapy for Dementia Patients: A Systematic Review.Carrion C, Folkvord F, Anastasiadou D, Aymerich M. Dement Geriatr Cogn Disord. 2018; 2018 Aug 9. PMID: 30092585.
Sleep and EEG Power Spectral Analysis in Three Transgenic Mouse Models of Alzheimer's Disease: APP/PS1, 3xTgAD, and Tg2576.Kent BA, Strittmatter SM, Nygaard HB. J Alzheimers Dis. 2018. PMID: 29991134.
Impact of the Presence of Select Cardiovascular Risk Factors on Cognitive Changes among Dementia Subtypes.Irimata KE, Dugger BN, Wilson JR. Curr Alzheimer Res. 2018. PMID: 29962344.
Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C. J Alzheimers Dis. 2018. PMID: 29914016.
Use of integrated imaging and serum biomarker profiles to identify subclinical dysfunction in pediatric cancer patients treated with anthracyclines.Toro-Salazar OH, Lee JH, Zellars KN, Perreault PE, Mason KC, Wang Z, Hor KN, Gillan E, Zeiss CJ, Gatti DM, Davey BT, Kutty S, Liang BT, Spinale FG. Cardiooncology. 2018; 2018 May 1. PMID: 29900007.
Sleep Disturbance and the Risk of Cognitive Decline or Clinical Conversion in the ADNI Cohort.Mecca AP, Michalak HR, McDonald JW, Kemp EC, Pugh EA, Becker ML, Mecca MC, van Dyck CH. Dement Geriatr Cogn Disord. 2018; 2018 Jun 8. PMID: 29886490.
The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1.Wang Q, Guo L, Thompson PM, Jack CR, Dodge H, Zhan L, Zhou J. J Alzheimers Dis. 2018. PMID: 29865049.
Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease.Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC. J Alzheimers Dis. 2018. PMID: 29614657.
Pathologically Confirmed Alzheimer's Disease in APOE ɛ2 Homozygotes is Rare but Does Occur.Stipho F, Jackson R, Sabbagh MN. J Alzheimers Dis. 2018. PMID: 29562509.
Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5.Brody AH, Strittmatter SM. Adv Pharmacol. 2018; 2017 Oct 25. PMID: 29413525.
Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis.Ramsey CM, Gnjidic D, Agogo GO, Allore H, Moga D. Alzheimers Dement (N Y). 2018; 2017 Nov 26. PMID: 29296658.
Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS).Weintraub S, Besser L, Dodge HH, Teylan M, Ferris S, Goldstein FC, Giordani B, Kramer J, Loewenstein D, Marson D, Mungas D, Salmon D, Welsh-Bohmer K, Zhou XH, Shirk SD, Atri A, Kukull WA, Phelps C, Morris JC. Alzheimer Dis Assoc Disord. 2018 Jan-Mar. PMID: 29240561.
Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment.Lin M, Gong P, Yang T, Ye J, Albin RL, Dodge HH. Alzheimer Dis Assoc Disord. 2018 Jan-Mar. PMID: 29227306.
Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease.Kirson NY, Scott Andrews J, Desai U, King SB, Schonfeld S, Birnbaum HG, Ball DE, Kahle-Wrobleski K. J Alzheimers Dis. 2018. PMID: 29154268.
Cortical β-amyloid burden, gray matter, and memory in adults at varying APOE ε4 risk for Alzheimer's disease.Mecca AP, Barcelos NM, Wang S, Brück A, Nabulsi N, Planeta-Wilson B, Nadelmann J, Benincasa AL, Ropchan J, Huang Y, Gelernter J, Van Ness PH, Carson RE, van Dyck CH. Neurobiol Aging. 2018 Jan; 2017 Oct 6. PMID: 29111487.
Dyslexic Characteristics of Chinese-Speaking Semantic Variant of Primary Progressive Aphasia.Ting SKS, Foo H, Chia PS, Hameed S, Ng KP, Ng A, Kandiah N. J Neuropsychiatry Clin Neurosci. 2018 Winter; 2017 Oct 24. PMID: 29061089.
Distressing Symptoms, Disability, and Hospice Services at the End of Life: Prospective Cohort Study.Gill TM, Han L, Leo-Summers L, Gahbauer EA, Allore HG. J Am Geriatr Soc. 2018 Jan; 2017 Sep 12. PMID: 28895118.
Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease.Qian W, Fischer CE, Schweizer TA, Munoz DG. Curr Alzheimer Res. 2018. PMID: 28847281.
Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E.Burke SL, Maramaldi P, Cadet T, Kukull W. Int J Geriatr Psychiatry. 2018 Jan; 2017 May 31. PMID: 28560728.

2017

Immune responses to the real world.Zeiss CJ, Brayton CF. Lab Anim (NY). 2017 Dec 29. PMID: 29297473.
Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1.Chiba K, Chien KY, Sobu Y, Hata S, Kato S, Nakaya T, Okada Y, Nairn AC, Kinjo M, Taru H, Wang R, Suzuki T. Mol Biol Cell. 2017 Dec 15; 2017 Nov 1. PMID: 29093025.
Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo.Sobu Y, Furukori K, Chiba K, Nairn AC, Kinjo M, Hata S, Suzuki T. Mol Biol Cell. 2017 Dec 15; 2017 Nov 1. PMID: 29093024.
Validation and diagnostic accuracy of predictive curves for age-associated longitudinal cognitive decline in older adults.Bernier PJ, Gourdeau C, Carmichael PH, Beauchemin JP, Verreault R, Bouchard RW, Kröger E, Laforce R Jr. CMAJ. 2017 Dec 4. PMID: 29203616.
A multiregional proteomic survey of the postnatal human brain.Carlyle BC, Kitchen RR, Kanyo JE, Voss EZ, Pletikos M, Sousa AMM, Lam TT, Gerstein MB, Sestan N, Nairn AC. Nat Neurosci. 2017 Dec; 2017 Nov 13. PMID: 29184206.
Objective features of subjective cognitive decline in a United States national database.Kielb S, Rogalski E, Weintraub S, Rademaker A. Alzheimers Dement. 2017 Dec; 2017 Jun 3. PMID: 28586648.
Moderating risk of Alzheimer's disease through the use of anxiolytic agents.Burke SL, O'Driscoll J, Alcide A, Li T. Int J Geriatr Psychiatry. 2017 Dec; 2016 Nov 2. PMID: 27805724.
Mental speed is associated with the shape irregularity of white matter MRI hyperintensity load.Lange C, Suppa P, Mäurer A, Ritter K, Pietrzyk U, Steinhagen-Thiessen E, Fiebach JB, Spies L, Buchert R. Brain Imaging Behav. 2017 Dec. PMID: 27796731.
Oxalate-curcumin-based probe for micro- and macroimaging of reactive oxygen species in Alzheimer's disease.Yang J, Zhang X, Yuan P, Yang J, Xu Y, Grutzendler J, Shao Y, Moore A, Ran C. Proc Natl Acad Sci U S A. 2017 Nov 21; 2017 Nov 6. PMID: 29109280.
Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology.Gowrishankar S, Wu Y, Ferguson SM. J Cell Biol. 2017 Oct 2; 2017 Aug 7. PMID: 28784610.
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis.Neu SC, Pa J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Ruiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen YL, Toga AW. JAMA Neurol. 2017 Oct 1. PMID: 28846757.
Societal and Family Lifetime Cost of Dementia: Implications for Policy.Jutkowitz E, Kane RL, Gaugler JE, MacLehose RF, Dowd B, Kuntz KM. J Am Geriatr Soc. 2017 Oct; 2017 Aug 17. PMID: 28815557.
Longitudinal Cognitive Profiles in Diabetes: Results From the National Alzheimer's Coordinating Center's Uniform Data.Sano M, Zhu CW, Grossman H, Schimming C. J Am Geriatr Soc. 2017 Oct; 2017 Aug 3. PMID: 28771679.
Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease.Salazar SV, Gallardo C, Kaufman AC, Herber CS, Haas LT, Robinson S, Manson JC, Lee MK, Strittmatter SM. J Neurosci. 2017 Sep 20; 2017 Aug 21. PMID: 28842420.
Proton Pump Inhibitors and Risk of Mild Cognitive Impairment and Dementia.Goldstein FC, Steenland K, Zhao L, Wharton W, Levey AI, Hajjar I. J Am Geriatr Soc. 2017 Sep; 2017 Jun 7. PMID: 28590010.
Cognitive decline associated with pathological burden in primary age-related tauopathy.Jefferson-George KS, Wolk DA, Lee EB, McMillan CT. Alzheimers Dement. 2017 Sep; 2017 Mar 16. PMID: 28322204.
Performance comparison of 10 different classification techniques in segmenting white matter hyperintensities in aging.Dadar M, Maranzano J, Misquitta K, Anor CJ, Fonov VS, Tartaglia MC, Carmichael OT, Decarli C, Collins DL. Neuroimage. 2017 Aug 15; 2017 Jul 3. PMID: 28602597.
Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice.Klein ZA, Takahashi H, Ma M, Stagi M, Zhou M, Lam TT, Strittmatter SM. Neuron. 2017 Jul 19. PMID: 28728022.
Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.Haas LT, Salazar SV, Smith LM, Zhao HR, Cox TO, Herber CS, Degnan AP, Balakrishnan A, Macor JE, Albright CF, Strittmatter SM. Cell Rep. 2017 Jul 5. PMID: 28683325.
Informatics Support for Basic Research in Biomedicine.Rindflesch TC, Blake CL, Fiszman M, Kilicoglu H, Rosemblat G, Schneider J, Zeiss CJ. ILAR J. 2017 Jul 1. PMID: 28838071.
Bridging the Gap between Reproducibility and Translation: Data Resources and Approaches.Zeiss CJ, Johnson LK. ILAR J. 2017 Jul 1. PMID: 28586416.
PET Imaging for Early Detection of Alzheimer's Disease: From Pathologic to Physiologic Biomarkers.Bao W, Jia H, Finnema S, Cai Z, Carson RE, Huang YH. PET Clin. 2017 Jul; 2017 May 2. PMID: 28576171.
A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging.Damisah EC, Hill RA, Tong L, Murray KN, Grutzendler J. Nat Neurosci. 2017 Jul; 2017 May 15. PMID: 28504673.
From Reproducibility to Translation in Neurodegenerative Disease.Zeiss CJ. ILAR J. 2017 Jul 1. PMID: 28444192.
Neuropsychological Testing in Pathologically Verified Alzheimer Disease and Frontotemporal Dementia: How Well Do the Uniform Data Set Measures Differentiate Between Diseases?Ritter AR, Leger GC, Miller JB, Banks SJ. Alzheimer Dis Assoc Disord. 2017 Jul-Sep. PMID: 28005562.
Early Activation of Experience-Independent Dendritic Spine Turnover in a Mouse Model of Alzheimer's Disease.Heiss JK, Barrett J, Yu Z, Haas LT, Kostylev MA, Strittmatter SM. Cereb Cortex. 2017 Jul 1. PMID: 27365298.
Targeted two-photon chemical apoptotic ablation of defined cell types in vivo.Hill RA, Damisah EC, Chen F, Kwan AC, Grutzendler J. Nat Commun. 2017 Jun 16; 2017 Jun 16. PMID: 28621306.
Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition.Musante V, Li L, Kanyo J, Lam TT, Colangelo CM, Cheng SK, Brody AH, Greengard P, Le Novère N, Nairn AC. Elife. 2017 Jun 14; 2017 Jun 14. PMID: 28613156.
Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample.Brenowitz WD, Hubbard RA, Keene CD, Hawes SE, Longstreth WT Jr, Woltjer RL, Kukull WA. Alzheimers Dement. 2017 Jun; 2016 Nov 19. PMID: 27870939.
A phase 3 trial of IV immunoglobulin for Alzheimer disease.Relkin NR, Thomas RG, Rissman RA, Brewer JB, Rafii MS, van Dyck CH, Jack CR, Sano M, Knopman DS, Raman R, Szabo P, Gelmont DM, Fritsch S, Aisen PS. Neurology. 2017 May 2; 2017 Apr 5. PMID: 28381506.
Absence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects With Alzheimer Disease.Williams EA, McGuone D, Frosch MP, Hyman BT, Laver N, Stemmer-Rachamimov A. J Neuropathol Exp Neurol. 2017 May 1. PMID: 28379416.
Neurofibrillary Tangle Stage and the Rate of Progression of Alzheimer Symptoms: Modeling Using an Autopsy Cohort and Application to Clinical Trial Design.Qian J, Hyman BT, Betensky RA. JAMA Neurol. 2017 May 1. PMID: 28288263.
C9orf72: At the intersection of lysosome cell biology and neurodegenerative disease.Amick J, Ferguson SM. Traffic. 2017 May; 2017 Mar 23. PMID: 28266105.
Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples.Brenowitz WD, Keene CD, Hawes SE, Hubbard RA, Longstreth WT Jr, Woltjer RL, Crane PK, Larson EB, Kukull WA. Neurobiol Aging. 2017 May; 2017 Jan 30. PMID: 28236716.
Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.Takahashi H, Klein ZA, Bhagat SM, Kaufman AC, Kostylev MA, Ikezu T, Strittmatter SM. Acta Neuropathol. 2017 May; 2017 Jan 9. PMID: 28070672.
Binding Sites for Amyloid-β Oligomers and Synaptic Toxicity.Smith LM, Strittmatter SM. Cold Spring Harb Perspect Med. 2017 May 1; 2017 May 1. PMID: 27940601.
Assessing medication burden and polypharmacy: finding the perfect measure.Gnjidic D, Tinetti M, Allore HG. Expert Rev Clin Pharmacol. 2017 Apr; 2017 Mar 8. PMID: 28271722.
Willingness to Be a Brain Donor: A Survey of Research Volunteers From 4 Racial/Ethnic Groups.Boise L, Hinton L, Rosen HJ, Ruhl MC, Dodge H, Mattek N, Albert M, Denny A, Grill JD, Hughes T, Lingler JH, Morhardt D, Parfitt F, Peterson-Hazan S, Pop V, Rose T, Shah RC. Alzheimer Dis Assoc Disord. 2017 Apr-Jun. PMID: 27779492.
Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.Gayle S, Landrette S, Beeharry N, Conrad C, Hernandez M, Beckett P, Ferguson SM, Mandelkern T, Zheng M, Xu T, Rothberg J, Lichenstein H. Blood. 2017 Mar 30; 2017 Jan 19. PMID: 28104689.
ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase).Andrade EC, Musante V, Horiuchi A, Matsuzaki H, Brody AH, Wu T, Greengard P, Taylor JR, Nairn AC. J Neurosci. 2017 Mar 8; 2017 Feb 6. PMID: 28167675.
Secondary Motor Cortex: Where 'Sensory' Meets 'Motor' in the Rodent Frontal Cortex.Barthas F, Kwan AC. Trends Neurosci. 2017 Mar; 2016 Dec 22. PMID: 28012708.
β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.Goldberg EL, Asher JL, Molony RD, Shaw AC, Zeiss CJ, Wang C, Morozova-Roche LA, Herzog RI, Iwasaki A, Dixit VD. Cell Rep. 2017 Feb 28. PMID: 28249154.
Cellular prion protein as a receptor for amyloid-β oligomers in Alzheimer's disease.Salazar SV, Strittmatter SM. Biochem Biophys Res Commun. 2017 Feb 19; 2016 Sep 14. PMID: 27639648.
Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson's disease.Zeiss CJ, Allore HG, Beck AP. PLoS One. 2017; 2017 Feb 9. PMID: 28182759.
Risk Factors Associated With Cognitive, Functional, and Behavioral Trajectories of Newly Diagnosed Dementia Patients.Jutkowitz E, MacLehose RF, Gaugler JE, Dowd B, Kuntz KM, Kane RL. J Gerontol A Biol Sci Med Sci. 2017 Feb; 2016 Apr 29. PMID: 27129917.
Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution.Nishi A, Matamales M, Musante V, Valjent E, Kuroiwa M, Kitahara Y, Rebholz H, Greengard P, Girault JA, Nairn AC. J Biol Chem. 2017 Jan 27; 2016 Dec 20. PMID: 27998980.
The Effect of Traumatic Brain Injury History with Loss of Consciousness on Rate of Cognitive Decline Among Older Adults with Normal Cognition and Alzheimer's Disease Dementia.Tripodis Y, Alosco ML, Zirogiannis N, Gavett BE, Chaisson C, Martin B, McClean MD, Mez J, Kowall N, Stern RA. J Alzheimers Dis. 2017. PMID: 28655133.
Bladder antimuscarinics and cognitive decline in elderly patients.Moga DC, Abner EL, Wu Q, Jicha GA. Alzheimers Dement (N Y). 2017 Jan. PMID: 28462390.
Predictors of Reversion from Mild Cognitive Impairment to Normal Cognition.Pandya SY, Lacritz LH, Weiner MF, Deschner M, Woon FL. Dement Geriatr Cogn Disord. 2017; 2017 Mar 17. PMID: 28301848.
Gender and Pathology-Specific Effect of Apolipoprotein E Genotype on Psychosis in Alzheimer's Disease.Kim J, Fischer CE, Schweizer TA, Munoz DG. Curr Alzheimer Res. 2017. PMID: 28219318.
Executive Dysfunction and Behavioral Symptoms Are Associated with Deficits in Instrumental Activities of Daily Living in Frontotemporal Dementia.Moheb N, Mendez MF, Kremen SA, Teng E. Dement Geriatr Cogn Disord. 2017; 2017 Jan 20. PMID: 28103593.
Risk Factors and Pathological Substrates Associated with Agitation/Aggression in Alzheimer's Disease: A Preliminary Study using NACC Data.Sennik S, Schweizer TA, Fischer CE, Munoz DG. J Alzheimers Dis. 2017. PMID: 27911311.
A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland.Moga DC, Taipale H, Tolppanen AM, Tanskanen A, Tiihonen J, Hartikainen S, Wu Q, Jicha GA, Gnjidic D. Drugs Aging. 2017 Jan. PMID: 27896799.
The Role of Cerebrovascular Disease on Cognitive and Functional Status and Psychosis in Severe Alzheimer's Disease.Kim J, Schweizer TA, Fischer CE, Munoz DG. J Alzheimers Dis. 2017. PMID: 27662301.

2016

Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity.Lombroso PJ, Ogren M, Kurup P, Nairn AC. F1000Res. 2016; 2016 Dec 29. PMID: 29098072.
Subtle changes in daily functioning predict conversion from normal to mild cognitive impairment or dementia: an analysis of the NACC database.Nowrangi MA, Rosenberg PB, Leoutsakos JS. Int Psychogeriatr. 2016 Dec; 2016 Aug 8. PMID: 27585497.
C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling.Amick J, Roczniak-Ferguson A, Ferguson SM. Mol Biol Cell. 2016 Oct 15; 2016 Aug 24. PMID: 27559131.
Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.Tong BC, Lee CS, Cheng WH, Lai KO, Foskett JK, Cheung KH. Sci Signal. 2016 Sep 6; 2016 Sep 6. PMID: 27601731.
Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.Onorati M, Li Z, Liu F, Sousa AMM, Nakagawa N, Li M, Dell'Anno MT, Gulden FO, Pochareddy S, Tebbenkamp ATN, Han W, Pletikos M, Gao T, Zhu Y, Bichsel C, Varela L, Szigeti-Buck K, Lisgo S, Zhang Y, Testen A, Gao XB, Mlakar J, Popovic M, Flamand M, Strittmatter SM, Kaczmarek LK, Anton ES, Horvath TL, Lindenbach BD, Sestan N. Cell Rep. 2016 Sep 6; 2016 Aug 24. PMID: 27568284.
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS. Ann Clin Transl Neurol. 2016 Sep; 2016 Aug 26. PMID: 27648456.
Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study.Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC. JAMA Neurol. 2016 Sep 1. PMID: 27454811.
Fast and slow transitions in frontal ensemble activity during flexible sensorimotor behavior.Siniscalchi MJ, Phoumthipphavong V, Ali F, Lozano M, Kwan AC. Nat Neurosci. 2016 Sep; 2016 Jul 11. PMID: 27399844.
Erasure of fear memories is prevented by Nogo Receptor 1 in adulthood.Bhagat SM, Butler SS, Taylor JR, McEwen BS, Strittmatter SM. Mol Psychiatry. 2016 Sep; 2015 Dec 1. PMID: 26619810.
Oligomers of Amyloid β Prevent Physiological Activation of the Cellular Prion Protein-Metabotropic Glutamate Receptor 5 Complex by Glutamate in Alzheimer Disease.Haas LT, Strittmatter SM. J Biol Chem. 2016 Aug 12; 2016 Jun 20. PMID: 27325698.
Methodology to Estimate the Longitudinal Average Attributable Fraction of Guideline-recommended Medications for Death in Older Adults With Multiple Chronic Conditions.Allore HG, Zhan Y, Cohen AB, Tinetti ME, Trentalange M, McAvay G. J Gerontol A Biol Sci Med Sci. 2016 Aug; 2016 Jan 8. PMID: 26748093.
Neuropsychiatric symptoms and Apolipoprotein E: Associations with eventual Alzheimer's disease development.Burke SL, Maramaldi P, Cadet T, Kukull W. Arch Gerontol Geriatr. 2016 Jul-Aug; 2016 Apr 14. PMID: 27111252.
Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum.Serrano-Pozo A, Qian J, Muzikansky A, Monsell SE, Montine TJ, Frosch MP, Betensky RA, Hyman BT. J Neuropathol Exp Neurol. 2016 Jun; 2016 Apr 22. PMID: 27105663.
Cognitive Aging Trajectories and Burdens of Disability, Hospitalization and Nursing Home Admission Among Community-living Older Persons.Han L, Gill TM, Jones BL, Allore HG. J Gerontol A Biol Sci Med Sci. 2016 Jun; 2015 Oct 28. PMID: 26511011.
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, Colonna M. J Exp Med. 2016 May 2; 2016 Apr 18. PMID: 27091843.
Defeating Alzheimer's disease and other dementias: a priority for European science and society.Winblad B, Amouyel P, Andrieu S, Ballard C, Brayne C, Brodaty H, Cedazo-Minguez A, Dubois B, Edvardsson D, Feldman H, Fratiglioni L, Frisoni GB, Gauthier S, Georges J, Graff C, Iqbal K, Jessen F, Johansson G, Jönsson L, Kivipelto M, Knapp M, Mangialasche F, Melis R, Nordberg A, Rikkert MO, Qiu C, Sakmar TP, Scheltens P, Schneider LS, Sperling R, Tjernberg LO, Waldemar G, Wimo A, Zetterberg H. Lancet Neurol. 2016 Apr. PMID: 26987701.
Lysosomes relax in the cellular suburbs.Gowrishankar S, Ferguson SM. J Cell Biol. 2016 Mar 14. PMID: 26975848.
Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology.Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, Adler CH, Beach TG, Trojanowski JQ. Acta Neuropathol. 2016 Mar; 2015 Dec 31. PMID: 26721587.
Trajectories of Disability Among Older Persons Before and After a Hospitalization Leading to a Skilled Nursing Facility Admission.Buurman BM, Han L, Murphy TE, Gahbauer EA, Leo-Summers L, Allore HG, Gill TM. J Am Med Dir Assoc. 2016 Mar 1; 2015 Nov 24. PMID: 26620073.
PET imaging evaluation of [(18)F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates.Hillmer AT, Zheng MQ, Li S, Scheunemann M, Lin SF, Holden D, Labaree D, Ropchan J, Teodoro R, Deuther-Conrad W, Carson RE, Brust P, Huang Y. Eur J Nucl Med Mol Imaging. 2016 Mar; 2015 Oct 12. PMID: 26455500.
Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease.Haas LT, Salazar SV, Kostylev MA, Um JW, Kaufman AC, Strittmatter SM. Brain. 2016 Feb; 2015 Dec 14. PMID: 26667279.
Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity.Yuan P, Grutzendler J. J Neurosci. 2016 Jan 13. PMID: 26758850.
Special Issue: Methods for Estimating Treatment Effects for Persons with Multiple Chronic Conditions.Allore H. Int J Stat Med Res. 2016. PMID: 27559427.
Long-Term Clinical Outcomes in Diabetic Rhesus Macaques (Macaca mulatta) Treated with Medroxyprogesterone Acetate for Endometriosis.Connolly MA, Trentalange M, Zeiss CJ. Comp Med. 2016. PMID: 27538865.
Demodex musculi Infestation in Genetically Immunomodulated Mice.Smith PC, Zeiss CJ, Beck AP, Scholz JA. Comp Med. 2016. PMID: 27538858.