Christopher H Van Dyck, MD

Professor of Psychiatry, Neurology, and Neuroscience; Director, Alzheimer's Disease Research Unit

Departments & Organizations

Dorothy Adler Geriatric Assessment Center

Interdepartmental Neuroscience Program

Office of Student Research

Psychiatry: Aging & Geriatric Psychiatry, Division of | Alzheimer's Disease Research Center (ADRC) | Alzheimer's Disease Research Unit

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience: Cognitive/Learning and Memory; Neural Disorders

Yale Medical Group


Christopher H. van Dyck, MD, is Professor of Psychiatry, Neurology, and Neurobiology, and Director of the Alzheimer's Disease

Research Unit at Yale. His research interests include therapeutic, neuroimaging

and genetic studies of Alzheimer's disease (AD) and healthy cognitive aging. Dr.

van Dyck is very active in AD therapeutic research. Since 1992 he has

participated in 80+ multicenter clinical trials for AD and MCI and has authored

several of the trial publications. He serves on the Steering Committees of the NIA Alzheimer's Disease Cooperative Study (ADCS) and Alzheimer's Disease Neuroimaging Initiative (ADNI). Dr. van Dyck’s other

significant scholarly contributions include dopamine transporter imaging in

healthy aging and the apolipoprotein E e4 Phenotype

of AD. In 2005 he received the "Compassion and Cure" Award from the Alzheimer's Association.

Education & Training

MD Northwestern University (1984)
BA Yale University (1978)
Resident Yale-New Haven Hospital
Fellow Yale University School of Medicine

Honors & Recognition

  • Best Doctors in New York (Top 2%), as Featured in New York MagazineCastle Connolly (2005), (2009)

  • “Compassion and Cure” AwardAlzheimer’s Association (2005)

  • Junior Investigator AwardAmerican Association for Geriatric Psychiatry (1996)

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Contact Info

Christopher H Van Dyck, MD
Patient Care Locations
Yale Alzheimer's Disease Research Unit1 Church Street, Ste Suite 600
New Haven, CT 06510
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Adler Geriatric Assessment Center874 Howard Avenue
New Haven, CT 06519
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Mailing Address
Yale University School of Medicine
One Church Street

New Haven, CT 06510

Alzheimer's Disease Research Unit

Research Image 1

Frequency of psychosis by ApoE e4 carrier status and dementia severity. Mini Mental State Examination (MMSE) score was used to classify AD patients as mild (MMSE>19, n=103), moderate (MMSE=12-19, n=121), or severe (MMSE<12, n=42). Separate multiple logistic regression analyses were performed for each severity category, with presence of psychosis as dependent variable and the following independent variables (in addition to e4 carrier status): age, sex, educational attainment, and MMSE. *Only at the severe stage was the presence of e4 significantly associated with psychosis (odds ratio [OR]=16.61, 95% CI=2.11-130.51, P=.008). (From Zdanys KF , et al. 2007.)