Slide 23

Raw single trial recording illustrating the effect of presentation of an artificial scotoma on the membrane potential of the cell. The bottom trace illustrates the continuous recording. Presentation of a high contrast sinewave grating results in a strong depolarization of the cell followed by adaptation. Presentation of an artificial scotoma over the classical receptive field results in a strong hyperpolarization, that slowly recovers over a period of 20-30 seconds.