Martin A Schwartz PhD

Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Biomedical Engineering and of Cell Biology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development

Office of Student Research

School of Engineering and Applied ScienceVascular Biology and Therapeutics ProgramCell BiologyInternal Medicine: Cardiovascular Medicine: Yale Cardiovascular Research Center: Schwartz Lab

Research Interests

Integrin signaling; Mechanotransduction; Atherosclerosis; Vascular remodeling; Heart disease; Extracellular matrix; Cell adhesion; Cytoskeleton; Cell-cell junctions; Fluid shear stress more...


  • B.A., New College of the University South Florida, 1975
  • Ph.D., Stanford University, 1979

Selected Publications

  • Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA. Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1. Curr Biol. 2013 Jun 3, 23:1024-30
  • Hoffman, B.D., Grashoff, C. and Schwartz, M.A. Dynamic molecular processes mediate cellular mechanotransduction. Nature. 2011, 475:316-323.
  • Grashoff C., Hoffman BD., Brenner MD., Zhou R., Parsons M., Yang MT., McLean MA., Sligar SG., Chen CS., Ha T. and Schwartz, MA.. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature, 2010,466:263-6.



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