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About Us

The Yale Center for Genomic Health is a center of excellence in human genomics, genetics, data science, and precision medicine. We are a diverse group of researchers bridging the Yale School of Medicine, the Yale New Haven Hospital and the broader Yale Health System. Our overall mission is to tackle the most pressing challenge in the field: how to translate increasingly powerful genomic technologies and increasingly vast data resources into meaningful improvements in healthcare, in a manner that equitably benefits people of all ancestry groups and ethnicities.

We lead efforts to develop and apply new technologies in genome sequencing, electronic health record integration, and artificial intelligence. We pursue cross-disciplinary, collaborative studies focused on gene discovery, disease mechanism, risk prediction, and health outcomes across a wide spectrum of health conditions and life stages. We are committed to reducing health disparities through the inclusion of diverse ancestry groups in our studies and through the development of unbiased computational methods.

We are the academic home of the Generations Project, which aims to enroll 100,000 patients from Connecticut to study the relationships between genes, environment, and health outcomes through the integrative analysis of genome sequences and electronic health records. We are actively enrolling patients in the Generations Project; volunteers interested in participating can find more information at Yale BioBank (YBB) - GENERATIONS. YCGH members also play leading roles in many other relevant projects, including large multi-institutional collaborations such as the Human Pangenome Project, the Centers for Common Disease Genomics, the Pediatric Cardiac Genomics Consortium, the International Common Disease Alliance, the Million Veterans Program, and the Psychiatric Genomics Consortium, among others.

Our Values

We aim to tackle scientific questions that benefit humanity. We believe that outstanding science is driven by curiosity, respect, mentorship, and diversity. We strive to create an inclusive community of faculty, staff, and students whose voices and contributions are valued and respected, and who better represent the communities we serve.