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Infectious Diseases | Men's Health | Women's Health, Phase II

Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Adults (PRIOH-1)

What is the purpose of this trial?

A randomized, open-label, multi-center, comparative trial, to assess the efficacy and safety of Pritelivir versus Foscarnet for the treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised subjects (PRIOH-1)

Pritelivir will be provided as 100 mg film-coated tablets. Pritelivir will be administered as a loading dose of 400 mg (4 x 100 mg) as first dose followed by a maintenance dose of 100 mg once daily (qd). Foscarnet will be given as intermittent infusions at a dose of 40 mg/kg every 8 hours or 60 mg/kg every 12 hours for a minimum of one hour duration for a maximum treatment duration of 28 days.

Contact Information

For more information about this study, including how to volunteer, contact Rodolfo Molina

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