NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol
Bones and Joints | Brain and Nervous System | Leukemia, not otherwise specified | Leukemia, other | Lymphoid Leukemia
What is the purpose of this trial?
This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists that has been shown to prolong survival. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with genetic changes or abnormalities (mutations) may benefit more from treatment which targets their tumor's particular genetic mutation, and may help doctors plan better treatment for patients with solid tumors or non-Hodgkin lymphomas.
- Ages1 year - 21 years
- Trial withChildren's Oncology Group (COG)
- Start Date02/11/2021
- End Date09/30/2027
- Last Updated07/15/2021
- Study HIC#2000022902