Nasal Vaccine May Aid Fight Against New Viral Variants
Akiko Iwasaki and her colleagues found that intranasal vaccination provided broad-based protection against heterologous respiratory viruses in mice, while so-called systemic immunization, which uses an injection to elicit body-wide protection, did not.Source: YaleNews
Improving the Diagnosis of Heart Disease in Women
Dr. Samit Shah is leading a team to demonstrate the effectiveness of validated, but not widely administered procedures for the many women who have reduced blood flow to the heart without blocked arteries or cholesterol build-up often associated with heart disease.
Virtual Reality Game Is an Effective Tool for Vaping Prevention Among Teens
The game prompts students to practice navigating peer pressure situations involving vaping. By encouraging teens to use their own voices in simulated situations, the researchers hoped they would become better prepared to face real-world scenarios.
Psychedelic Spurs Growth of Neural Connections Lost in Depression
In a new study, Yale researchers show that a single dose of psilocybin given to mice prompted an immediate and long-lasting increase in connections between neurons. The findings are published July 5 in the journal Neuron.Source: Yale News
Sex-specific Immune Response in COVID-19 Linked to Cellular Metabolism
Researchers studying COVID-19 patients have found a metabolic pathway that is highly correlated with immune responses only in male patients, a group known to be more likely to suffer severe cases and die of the disease, representing a potential target for therapeutic intervention.Source: Yale News
WHRY Funds Study on How CBD Affects the Brain
Women’s Health Research at Yale announced funding to investigate how the presumably non-intoxicating cannabis ingredient cannabidiol (CBD) affects the brain, and if it affects women and men differently. CBD use is growing in popularity exponentially, yet the safety and effectiveness of this non-regulated category of products are unknown.
WHRY Launches Studies on Endometrial Cancer, Addiction to Opioids, and Stroke
While continuing to focus on the impacts of COVID-19, the center has enlarged its research portfolio to include new projects on the prevention of endometrial cancer in a growing cohort of women at high risk, non-opioid pain management following a cesarean section for women with opioid use disorder who are in recovery, and sex differences in stroke.
Yale Researchers Find Where Stress Lives
Yale researchers have found a neural home of the feeling of stress people experience, an insight that may help people deal with the debilitating sense of fear and anxiety that stress can evoke, Yale researchers report May 27 in the journal Nature Communications.
New Imaging Tool Helps Researchers See Extent of Alzheimer’s Early Damage
New imaging technology allows scientists to see the widespread loss of brain synapses in early stages of Alzheimer’s disease, a finding that one day may aid in drug development, according to a new Yale University study.Source: Yale News
Krystal Co-Author of NEJM Article That Tracks Symptom Improvement in Patients With Schizophrenia
Patients with schizophrenia demonstrated improvement on a scale used to measure symptom severity after taking a drug being tested in a clinical trial, according to an article published online in the New England Journal of Medicine and co-authored by John H. Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and Chair of the Yale Department of Psychiatry at Yale School of Medicine
Deadlier Colon Cancer Develops Differently in Women and Men
WHRY-affiliated researchers have found that colon cancer tumor cells produce energy for growth differently in women and men, and that this difference is associated with a more aggressive form of tumor growth with a higher incidence in women.
Yale School of Medicine Maintains its High National Ranking in Federal Research Funding
The 2019 total, $451,476,354, continues the school’s position in the top ten among U.S. medical schools that it has maintained each year since 2001. YSM ranked first in funding for psychiatry and dermatology; third for public health/preventive medicine and emergency medicine; fifth for radiology; sixth for neurology and ob-gyn; seventh for neurosurgery; and ninth for biochemistry, genetics, and internal medicine.
Yale Launches Comprehensive DNA Sequencing Project, With Aim of Predicting, Preventing, and Treating Gene-related Diseases
Generations, a collaboration between Yale School of Medicine and Yale New Haven Health System, is one of the largest DNA sequencing projects of its kind in the United States.
Yale-developed Scorecard Promotes Better Clinical Trial Data Sharing
A tool developed by researchers at Yale, Stanford, and Bioethics International can promote greater sharing of clinical trial data by pharmaceutical companies. While nearly one-third of the companies that the researchers assessed met standards for sharing data, others could be more transparent to the benefit of science and the public, the researchers said.