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Children's and/or Child/Parent Studies Enrolling at Yale

March 01, 2024

Be Part of Clinical Research at Yale

Are you a first-time mom with a 4- to 6- month-old baby?

Help us understand infants and their development in a new online study!

We are looking for first-time moms of 4- to 6-month-old infants to participate in a new online study with the Yale Child Study Center from the comfort of your home! We are interested in discovering more about the way moms understand infants and in how your baby develops. This study includes 2 virtual visits over zoom: one with you, and another one with you and your baby! If you recently had your first baby, you may be eligible to participate.

You will receive up to $75 in gift-cards as compensation for your time.

To learn more or to see if you are eligible to participate, please email: becomingaparent@yale.edu or call: (203) 590-7578.

Sponsored by Yale University School of Medicine; HIC# 2000028355


Does your 12- to 22-year-old have obesity or at risk for developing obesity?

Our research team in Pediatric Endocrinology at Yale is studying what causes fatty liver disease and how sugars are playing a role on liver fat content in children and adolescents with obesity. We would like to understand why some kids develop fatty liver and others do not. Nonalcoholic fatty liver disease (NAFLD) is the leading cause of liver disease in pediatrics with an estimate of about 7 million children and adolescents affected in the US. Early onset fatty liver can mean many years of disease, predisposing youth to develop complications early in life.

We are looking for teenagers and young adults between the ages of 12-22, obese (BMI>30), and identify as Hispanic and/or Black/African American. Hispanic youth show the highest prevalence of NAFLD (~45%) compared to Non-Hispanic Blacks (NHB) (~13%). Understanding the mechanisms leading to the different susceptibility of ethnic groups to accumulate intrahepatic fat will provide important insights in the pathophysiology of fatty liver in kids. We are looking to include the group with the highest rate of fatty liver, Hispanic youths, and a group with the lowest rate Black/African American to gain a better understanding of fatty liver disease.

Participants will be asked to do 3 separate research study visits and follow up visits every 6 months after the research study visits.

Participants may be compensated up to $1380.

To learn more or to see if your child is eligible, please contact Ermena Refugjati, CRA at Ermena.Refugjati@yale.edu.

Sponsored by the National Institute of Minority Health and Health Disparities (NIMHD); HIC# 200028731


Does your 13-17 year old have treatment resistant depression?

Yale is conducting a study to examine the safety, efficacy, response predictors, and post treatment trajectory of adolescents (13–17 years old) with treatment-resistant depression and high suicide risk following a conservative repeat dosing Ketamine infusion paradigm compared to an active control, Midazolam. Those who are randomized to Midazolam and remain ill have the option to cross-over to Ketamine in the open phase.

All participants will be followed closely for 4 months post-treatment and treated with standard of care depression treatment (medication management and cognitive behavioral therapy). Brain-based predictors of anti-suicidal responses will be assessed via connectome predictive modeling and examining functional brain circuits via fMRI before and after treatment.

To learn more about how this study may benefit your patients, contact Brooke Rivera, Clinical Coordinator, Yale Pediatric Depression Lab at (203) 974-2241 or email PediDepression@yale.edu.

Sponsored by the National Institute of Health; HIC# 200029003


Is your child aged 12-18 and you are noticing a recent change in their thinking, behavior, or experiences?

Pro-Net Study

If your child is between the ages of 12 and 18 and has recently experienced changes in their thinking, behavior, or experiences, they may qualify for this study. These changes include confusion between reality and imagination, feeling a lack of control over your thoughts or ideas, being suspicious or paranoid, experiencing unreal sensations like hearing sounds or seeing things that aren't there, and having difficulty communicating clearly.

Participants in this study will undergo an initial screening visit, 2 MRI scans, and 2 sets of blood work. Additionally, they will be asked questions about their experiences and emotional well-being.

Total compensation of up to $1000 is provided.

To inquire further or determine eligibility for participation, please contact us at 203-200-8997 or email pronetstudy@yale.edu.

Sponsored by National Institute of Mental Health (NIMH); HIC# 2000029159


All of Us Research Program

The All of Us Research Program is a large research program. The goal is to help researchers understand more about why people get sick or stay healthy by creating a biorepository.

People who join will give us information about their health, habits, and what it’s like where they live. By looking for patterns, researchers may learn more about what affects people’s health. If you decide to join All of Us, we will ask you to share different kinds of information like your name and where you live, questions about your family, home, and work. If you have an Electronic Medical Record, we may ask you for access. We will also ask you to come in for physical measurements like, height, weight, hip and waist circumference, and blood pressure, and heart rate. We will also ask you to provide blood and urine samples, or saliva.

Total Compensation: $25

If interested, please contact: allofus@yale.edu or call 203-785-5977

Sponsored by University of California, San Diego; HIC# 2000034651


Brain Imaging Study of Emotion Regulation in Children

If you have a child who is 9 to 12 years old, they may be eligible to participate in a study that examines your child’s social and emotional skills. This research will lead to new ways of understanding how children processes and regulate their emotions.

The study will require two visits. At each visit you and your child will complete questionnaires, and your child will participate in an fMRI scan. Functional magnetic resonance imaging (fMRI) is a technique for measuring and mapping brain activity that is noninvasive and safe. You will also receive a free psychoeducational assessment describing your child’s social and emotional development. The study is conducted at the Yale Child Study Center by caring and supportive research staff.

Eligibility:

  • Between the ages of 9 - 12
  • Significant levels of disruptive behavior (anger outbursts, irritability, noncompliance, easily frustrated) OR NO significant levels of disruptive behavior.
  • Be able to complete fMRI research procedure
  • Be able to commute to New Haven, CT

Compensation up to $100.

To learn more please contact our team at 203-737-6866 or email: emotion@yale.edu

Sponsored by National Institute of Mental Health (NIMH); Yale University School of Medicine; HIC# 2000031303


Do you have a child with ADHD?

The Cognitive and Affective Neuroscience Lab at Yale University is conducting a study looking at whether mindfulness helps children and adolescents with ADHD, in comparison to medication, or medication and mindfulness together.

We are looking for kids between 7 and 13 with ADHD, or who might have ADHD, and are interested in participating.

The study involves an online interview to confirm you have ADHD, online questionnaires and short tests, and then either in-person mindfulness sessions (16), or several online medication visits, or both. Afterwards, you will fill out online questionnaires and do short tests twice more.

You may be paid up to $480 for participation.

To learn more or see if you are eligible to participate, call 475-441-3920 or email mbatc@yale.edu.

Sponsored by National Center for Complementary and Integrative Health; HIC#: 2000020705


Does your child make unusual movements?

If your child is under the age of 4 and makes unusual movements with his or her hands, fingers, feet, or whole body, and has no other major developmental delays or concerns, he or she may be eligible to participate in a new study. Participation involves two visits that include developmental assessments and watching videos.

Participants will receive a clinical evaluation and are compensated up to $100. Free and secure parking is provided.

For more information, contact Gitta Selva at (203) 764-5933, email sanalab@yale.edu or visit https://medicine.yale.edu/lab/chawarska/participate/.

Research at the Yale Child Study Center

Sponsored Yale University School of Medicine HIC# 0808004146


Does your child have chronic tics or Tourette Syndrome?

If your child is 10-16 years old with chronic tics, they may be eligible to receive neurofeedback treatment. We use a form of neurofeedback that involves monitoring brain activity via fMRI. The purpose of this study is to determine if our neurofeedback intervention can reduce tic symptoms and improve our understanding of Tourette Syndrome.

Participation can result in compensation up to $880.

If you and your child are interested in participating in this study, please click here..

If you have any further questions or concerns, please contact us at Hampson.lab@yale.edu, or (203)-737-6055.

Sponsored by National Institute of Mental Health, Department of Human Health Services HIC #: 2000033043


Is your child between the ages of 10-14 years?

We are studying how children with and without anxiety pay attention to pictures or faces. If eligible, your child will complete computer tasks while we measure their attention. You and your child will also respond to surveys.

Compensation up to $350

To learn more or to see if you are eligible to participate, please call 203-737-4644 or email anxiety.csc@yale.edu.

Sponsored by National Institute of Mental Health; HIC# 2000029999


Does your child often feel nervous, scared, or worried in social situations?

The Anxiety & Mood Disorders Program is testing the effects of a brief computer-based training that targets attentional processes to reduce social anxiety in children, 10-14 years old.

You may be paid up to $600 for participation.

To learn more or see if you are eligible to participate, call 203-737-4644 or email anxiety.csc@yale.edu.

Sponsored by National Institute of Mental Health; HIC#: 2000025143


Help for childhood anxiety available

Does your child often feel nervous, scared, or worried? Participate in a research study for childhood anxiety comparing two effective treatments – Cognitive Behavioral Therapy (CBT) and Supportive Parenting for Anxious Childhood Emotions (SPACE) for children 6-12 years old.

You may be paid up to $250 for participation.

To learn more or see if you are eligible to participate, call 203-737-4644 or email anxiety.csc@yale.edu.

Sponsored by National Institute of Mental Health; HIC#: 2000023649


Is your child irritable or easily frustrated?

If you have a child who is 8 to 15 years old and is irritable and has low frustration tolerance, they may be eligible to participate in a non-invasive fMRI study. The study includes an initial clinical evaluation and follow-up assessments 6, 12, and 24 months later.

Healthy Volunteers Needed too.

If you have a child who is 8 to 15 years old, they may be eligible to participate in a non-invasive fMRI study. The study includes an initial clinical evaluation and follow-up assessments 6, 12, and 24 months later.

Compensation is up to $640.

For more information contact Grace Cotter at (203) 646-3830 or email affectiveyouth@yale.edu.

Sponsored by Charles H. Hood Foundation; National Institute of Mental Health (NIMH); Yale University School of Medicine; HIC#: 2000025557


Do you have a 9- to 12-month-old infant?

We are looking for tobacco-smoking and non-smoking mothers with a 9- to 12-month-old infant. Volunteers will be mothers who complete two, 2-hour long visits at the Yale Child Study Center. During the first visit, volunteers will complete some questionnaires, then some play time and a free developmental assessment with their infant. During the second visit, volunteers (not their infants) will complete a simple computer task while we safely measure brain activity as well as completing some more questionnaires and cognitive tasks. There will also be some questionnaires to complete between visits.

Volunteers will be compensated $50 after each visit, for a total of $100. Travel compensation is available too.

To learn more please contact The Before and After Baby Lab (BABL) at (203) 901-1029 or Email: thebabl@yale.edu.

Sponsored by National Institute on Drug Abuse (NIDA); HIC# 2000031080


Do you have a teenager diagnosed with Depression or Schizophrenia?

Help us learn more about how adolescents with depression and schizophrenia think and feel

If you have a teen 13 to 17 years of age, right-handed, with a history of depression OR schizophrenia and no major medical conditions, they may be eligible to participate in this research study. The goal is to understand how people their age think, feel and behave. This study will have a few visits spread across 18 months, including at least 2 MRI scans, clinical interviews, and some computer tests.

Compensation up to $650.

Healthy Teen Volunteers Also Needed.

To learn more or see if you are eligible to participate, email ChoLab@yale.edu or call (203) 815-9874.

Sponsored by the National Institute of Mental Health (NIMH); National Institute on Alcohol Abuse and Alcoholism (NIAAA); Rutgers, The State University of New Jersey; Simons Foundation; YCCI Pilot Project Grant; Yale University School of Medicine; HIC# 1111009332


Is your teen caught in a cycle of binge eating and purging? Do they go to extremes to lose weight or control their weight?

Teen Bulimia and Overweight Online Treatment Study

If your teen is 12-19 years old, has overweight or obesity, and is caught in a cycle of binge eating and purging, they may be eligible to participate in a free and confidential treatment study testing talk therapy (behavioral treatment).

Participants will receive compensation up to $225.

To learn more or see if your teen is eligible to participate, please call the Yale Teen Program of Weight, and Eating Research (Teen POWER) at (203) 785-7210, visit m.yale.edu/teenpower, or email teenpower@yale.edu

Sponsored by the National Eating Disorders Association (NEDA); HIC# 200033150


Adolescents with higher weight seeking treatment for bulimia nervosa

This study will test the feasibility and acceptability of two treatments for adolescents with higher weight seeking treatment for bulimia nervosa. Bulimia nervosa is when individuals binge eat (overeat while feeling like they lost control) and purge (do something extreme or unhealthy to lose weight or prevent weight gain). Bulimia nervosa happens across different ages and body sizes.

This study is focusing on adolescents who have a larger body size (overweight or obesity, or recent substantial weight loss). Adolescents will receive treatment that is 4 months of 45-minute sessions, weekly. Treatment will occur over telehealth (e.g., zoom), and the whole study is online.

To learn more please contact Yale Teen Power at 203-785-7821 or email: teenpower@yale.edu.

Sponsored by National Eating Disorders Association; Yale University School of Medicine; HIC# 2000033150


Do you have a child with autism and irritability or upset mood?

Comprehensive Therapy for Irritability in Adolescents with Autism

If you have a child who is 12-19 years old, has been diagnosed with autism spectrum disorder (ASD), and has significant levels of irritability or disruptive behavior (e.g., easily frustrated, meltdowns, anger outbursts), they may be eligible to participate in a free and confidential study.

Study includes free assessment of autism and 15 weekly sessions of therapy (remote or in-person).

Compensation of up to $250 for completion of study.

To learn more or see if your child is eligible, please contact the Sukhodolsky Lab (Sukhodolsky.Lab@yale.edu) or all 203-737-7662.

Sponsored by Department of the Army; Yale University School of Medicine Yale; HIC #0102012121


Help discover possible future treatments for irritability associated with autism

Children with or without intellectual disability may be able to take part if he or she:

  • Is 13 - 17 years old with established professional diagnosis of Autism Spectrum Disorder (ASD)
  • Speaks fluent English, has a primary caregiver also fluent and willing to help answer questions and complete study activities
  • Other criteria applicable – please contact us to learn more

The TAPESTRY Study measures effects of an investigational medication on irritability associated with autism.

Reach us online or directly via email, phone, or text: Dr. Roger Jou, 203-927-3970 (text/talk), roger.jou@yale.edu

Sponsored by Axial; HIC#: 2000031483


Would you like to learn about your baby's emotional development? Do you have an older child or other family member with autism spectrum disorder (ASD)?

You can play an important role in research discovery by enrolling your baby in a study on early emotional development. We are recruiting infants 4 months of age or younger who have an older sibling or other relative with ASD.

Participation involves brief visits that include developmental assessments, watching videos, and play-based activities to assess emotional development from 4 months through 30 months of age. Follow your child’s individual development along with our clinical and research staff.

Families are compensated up to $300 for study participation. Free, safe, and secure parking is provided.

For more information and to learn about eligibility, contact Gitta Selva at (203) 764-5933, email us at sanalab@yale.edu, or visit https://medicine.yale.edu/lab/chawarska/participate/.

Research at the Yale Child Study Center

Sponsored by National Institute of Mental Health (NIMH); HIC# 2000031163


The Autism Biomarkers Consortium for Clinical Trials (ABC-CT)

The McPartland Lab at the Yale Child Study Center has a clinical study available that examines your child's social, communication, and cognitive skills. This research will lead to new methods to develop, track, and assess treatments in Autism Spectrum Disorder (ASD).

We are currently recruiting both typically developing children and children with a diagnosis of autism spectrum disorder between the ages of 6 to 11 years old.

You will receive a psychoeducational evaluation describing your child's development over six months as well as compensation up to $300 for participating in the study.

To learn more about the study or to participate, please call us at 203-785-6108 or email our team at abc-ct@yale.edu.

Sponsored by National Institute of Mental Health (NIH) and the Foundation for the National Institutes of Health (FNIH) HIC# 2000032247


Are you a parent or guardian of a child with Autism Spectrum Disorder (ASD)? Are you an adult diagnosed with ASD?

SPARK study at Yale - all ages welcome

SPARK is a growing community of individuals, families, and researchers on a mission to speed up the understanding of autism. Our aims are to:

  • Collect DNA from saliva samples and information through surveys from 50,000 people with autism and both of their parents and share that data with researchers.
  • Make breakthroughs that were never before possible and return our findings to you.
  • SPARK is sponsored by the Simons Foundation Autism Research Initiative (SFARI) and Yale is one of more than 30 participating hospitals and clinics across the country.

Why join SPARK?

  • Find possible genetic causes of autism in your own family and power future autism research for years to come.
  • Join other autism research studies and get updates on the latest autism research.
  • Connect with a community of 1400 SPARK participants in our region!

You can receive up to $50 Amazon gift card for participation.

Registration can be completed entirely online and from home at www.SPARKforAutism.org/Yale or by scheduling an appointment with the Yale study team. To participate, simply register online and consent to the study. Saliva kits will be mailed to you and provided with return packaging. If you have questions call (203) 785-7539 or email sparkforautism@yale.edu.

Sponsored by Simons Foundation; HIC#2000024931


The Clinical Neuroscience of Autism Spectrum Disorder (ASD)

If you have a child between the ages of 6-18 years of age, you can play an important role in research by participating in our study to help us learn about brain development. The McPartland Lab at the Yale School of Medicine is seeking individuals with Autism Spectrum Disorder and/or Intellectual Disability, and Typically Developing male children.

Participants will receive a clinical evaluation and report, as well as compensation up to $120.

To learn more please contact our team at (203) 737-3439 or email autism@yale.edu.

Sponsored by Yale University School of Medicine; HIC# 0303025065

Submitted by Lisa Brophy on February 08, 2024